{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:57:35Z","timestamp":1792195055459,"version":"4.4.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Journal"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.bj.2023.100625","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T09:48:19Z","timestamp":1687686499000},"page":"100625","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Gut mycobiome in metabolic diseases: Mechanisms and clinical implication"],"prefix":"10.1016","volume":"47","author":[{"given":"Xingyu","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5008-2153","authenticated-orcid":false,"given":"Jun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.jhep.2019.06.021","article-title":"The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: a systematic review and meta-analysis","volume":"71","author":"Younossi","year":"2019","journal-title":"J Hepatol"},{"key":"10.1016\/j.bj.2023.100625_bib2","series-title":"Obesity. Our world in data","author":"Roser","year":"2017"},{"key":"10.1016\/j.bj.2023.100625_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2019.107843","article-title":"Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the international diabetes federation diabetes atlas","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res Clin Pract"},{"issue":"7121","key":"10.1016\/j.bj.2023.100625_bib4","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nature05482","article-title":"Mechanisms linking obesity to insulin resistance and type 2 diabetes","volume":"444","author":"Kahn","year":"2006","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib5","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/hep.30429","article-title":"Modulation of insulin resistance in nonalcoholic fatty liver disease","volume":"70","author":"Khan","year":"2019","journal-title":"Hepatology"},{"issue":"7285","key":"10.1016\/j.bj.2023.100625_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nature08821","article-title":"A human gut microbial gene catalogue established by metagenomic sequencing","volume":"464","author":"Qin","year":"2010","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib7","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/s41574-019-0156-z","article-title":"Gut microbial metabolites in obesity, NAFLD and T2DM","volume":"15","author":"Canfora","year":"2019","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.bj.2023.100625_bib8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.mib.2021.04.004","article-title":"The intestinal mycobiome as a determinant of host immune and metabolic health","volume":"62","author":"Gutierrez","year":"2021","journal-title":"Curr Opin Microbiol"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib9","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3390\/jof7040274","article-title":"Fungi and fungal metabolites for the improvement of human and animal nutrition and health","volume":"7","author":"Dufoss\u00e9","year":"2021","journal-title":"J Fungi (Basel)"},{"issue":"7121","key":"10.1016\/j.bj.2023.100625_bib10","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nature05485","article-title":"Inflammation and metabolic disorders","volume":"444","author":"Hotamisligil","year":"2006","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059474","article-title":"Plant and fungal diversity in gut microbiota as revealed by molecular and culture investigations","volume":"8","author":"Gouba","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bj.2023.100625_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/srep14600","article-title":"Obesity changes the human gut mycobiome","volume":"5","author":"Mar Rodriguez","year":"2015","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib13","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1007\/s00284-018-1438-8","article-title":"Fungal diversity of human gut microbiota among eutrophic, overweight, and obese individuals based on aerobic culture-dependent approach","volume":"75","author":"Borges","year":"2018","journal-title":"Curr Microbiol"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib14","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/jhn.12864","article-title":"The intestinal mycobiota and its relationship with overweight, obesity and nutritional aspects","volume":"34","author":"Garcia-Gamboa","year":"2021","journal-title":"J Hum Nutr Diet"},{"key":"10.1016\/j.bj.2023.100625_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105894","article-title":"Profiling of potential pathogenic candida species in obesity","volume":"174","author":"Shoukat","year":"2023","journal-title":"Microb Pathog"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib16","article-title":"Maturational patterns of the infant gut mycobiome are associated with early-life body mass index","volume":"4","author":"Gutierrez","year":"2023","journal-title":"Cell Rep Med"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib17","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/cob.12079","article-title":"Baker's yeast (Saccharomyces cerevisiae) antigen in obese and normal weight subjects","volume":"5","author":"Salamati","year":"2015","journal-title":"Clin Obes"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib18","doi-asserted-by":"crossref","first-page":"9624","DOI":"10.1038\/s41598-020-66598-2","article-title":"Revealing links between gut microbiome and its fungal community in Type 2 Diabetes Mellitus among Emirati subjects: a pilot study","volume":"10","author":"Al Bataineh","year":"2020","journal-title":"Sci Rep"},{"issue":"12","key":"10.1016\/j.bj.2023.100625_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243077","article-title":"Gut mycobiomes are altered in people with type 2 Diabetes Mellitus and Diabetic Retinopathy","volume":"15","author":"Jayasudha","year":"2020","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib20","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.3390\/nu13041066","article-title":"Analysis of the gut mycobiome in adult patients with type 1 and type 2 diabetes using next-generation sequencing (NGS) with increased sensitivity-pilot study","volume":"13","author":"Salamon","year":"2021","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib21","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/s42003-023-04591-x","article-title":"Abnormal proliferation of gut mycobiota contributes to the aggravation of Type 2 diabetes","volume":"6","author":"Bao","year":"2023","journal-title":"Commun Biol"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib22","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/oby.23073","article-title":"Fecal fungi dysbiosis in nonalcoholic fatty liver disease","volume":"29","author":"You","year":"2021","journal-title":"Obesity (Silver Spring)"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib23","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.jhep.2021.11.029","article-title":"The fecal mycobiome in non-alcoholic fatty liver disease","volume":"76","author":"Demir","year":"2022","journal-title":"J Hepatol"},{"issue":"21","key":"10.1016\/j.bj.2023.100625_bib24","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.3390\/cells11213390","article-title":"Endogenous ethanol and triglyceride production by gut Pichia kudriavzevii, Candida albicans and Candida glabrata yeasts in non-alcoholic steatohepatitis","volume":"11","author":"Mbaye","year":"2022","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib25","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00645-17","article-title":"Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa","volume":"86","author":"Richardson","year":"2018","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib26","doi-asserted-by":"crossref","first-page":"627","DOI":"10.4049\/jimmunol.1800515","article-title":"IL-36 and IL-1\/IL-17 drive immunity to oral candidiasis via parallel mechanisms","volume":"201","author":"Verma","year":"2018","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib27","doi-asserted-by":"crossref","first-page":"4260","DOI":"10.1038\/s41467-018-06607-1","article-title":"The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes","volume":"9","author":"Kasper","year":"2018","journal-title":"Nat Commun"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib28","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.jhep.2017.01.022","article-title":"NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice","volume":"66","author":"Mridha","year":"2017","journal-title":"J Hepatol"},{"issue":"11","key":"10.1016\/j.bj.2023.100625_bib29","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1007\/s00125-013-3023-9","article-title":"Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue","volume":"56","author":"Esser","year":"2013","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib30","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nm.2279","article-title":"The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance","volume":"17","author":"Vandanmagsar","year":"2011","journal-title":"Nat Med"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib31","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1084\/jem.20081463","article-title":"Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis","volume":"206","author":"Conti","year":"2009","journal-title":"J Exp Med"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib32","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.4049\/jimmunol.1302265","article-title":"Role of neutrophils in IL-17-dependent immunity to mucosal candidiasis","volume":"192","author":"Huppler","year":"2014","journal-title":"J Immunol"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib33","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1478-3231.2011.02639.x","article-title":"Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease","volume":"32","author":"Alkhouri","year":"2012","journal-title":"Liver Int"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib34","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1002\/hep.26746","article-title":"IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice","volume":"59","author":"Harley","year":"2014","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib35","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.cytogfr.2010.10.005","article-title":"IL-17 in obesity and adipogenesis","volume":"21","author":"Ahmed","year":"2010","journal-title":"Cytokine Growth Factor Rev"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib36","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/cmi.2010.5","article-title":"Th17 cells and their associated cytokines in liver diseases","volume":"7","author":"Lafdil","year":"2010","journal-title":"Cell Mol Immunol"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib37","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4161\/21505594.2014.988097","article-title":"Candida parapsilosis produces prostaglandins from exogenous arachidonic acid and OLE2 is not required for their synthesis","volume":"6","author":"Grozer","year":"2015","journal-title":"Virulence"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib38","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1128\/IAI.69.5.2957-2963.2001","article-title":"Pathogenic yeasts Cryptococcus neoformans and Candida albicans produce immunomodulatory prostaglandins","volume":"69","author":"Noverr","year":"2001","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib39","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2020.1830693","article-title":"Therapeutic manipulation of gut microbiota by polysaccharides of Wolfiporia cocos reveals the contribution of the gut fungi-induced PGE(2) to alcoholic hepatic steatosis","volume":"12","author":"Sun","year":"2020","journal-title":"Gut Microb"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib40","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1128\/IAI.00232-07","article-title":"Characterization of prostaglandin E2 production by Candida albicans","volume":"75","author":"Erb-Downward","year":"2007","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1194\/jlr.P055640","article-title":"Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis","volume":"56","author":"Loomba","year":"2015","journal-title":"J Lipid Res"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib42","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3892\/ijmm.2021.4947","article-title":"Role of 2-series prostaglandins in the pathogenesis of type 2 diabetes mellitus and non-alcoholic fatty liver disease (Review)","volume":"47","author":"Wang","year":"2021","journal-title":"Int J Mol Med"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib43","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/hep.23064","article-title":"Aggravation by prostaglandin E2 of interleukin-6-dependent insulin resistance in hepatocytes","volume":"50","author":"Henkel","year":"2009","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib44","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1089\/jmf.2014.0048","article-title":"Green tea lowers hepatic COX-2 and prostaglandin E2 in rats with dietary fat-induced nonalcoholic steatohepatitis","volume":"18","author":"Chung","year":"2015","journal-title":"J Med Food"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153751","article-title":"Prostaglandin E2 exerts multiple regulatory actions on human obese adipose tissue remodeling, inflammation, adaptive thermogenesis and lipolysis","volume":"11","author":"Garc\u00eda-Alonso","year":"2016","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib46","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1038\/ijo.2015.34","article-title":"Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans","volume":"39","author":"Virtue","year":"2015","journal-title":"Int J Obes"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib47","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1007\/s00535-013-0758-5","article-title":"Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease","volume":"48","author":"Kawano","year":"2013","journal-title":"J Gastroenterol"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib48","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/s42003-021-01820-z","article-title":"The gut mycobiome of healthy mice is shaped by the environment and correlates with metabolic outcomes in response to diet","volume":"4","author":"Mims","year":"2021","journal-title":"Commun Biol"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib49","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41572-018-0014-7","article-title":"Alcoholic liver disease","volume":"4","author":"Seitz","year":"2018","journal-title":"Nat Rev Dis Prim"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0009570","article-title":"Role of alcohol metabolism in non-alcoholic steatohepatitis","volume":"5","author":"Baker","year":"2010","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib51","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/j.cmet.2019.11.006","article-title":"Fatty liver disease caused by high-alcohol-producing Klebsiella pneumoniae","volume":"30","author":"Yuan","year":"2019","journal-title":"Cell Metabol"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib52","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/hep.26093","article-title":"Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH","volume":"57","author":"Zhu","year":"2013","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib53","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.3390\/nu13031013","article-title":"Characterization of gut microbiome in Korean patients with metabolic associated fatty liver disease","volume":"13","author":"Oh","year":"2021","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib54","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1740-0929.2012.01035.x","article-title":"Interaction between lactic acid bacteria and yeasts in airag, an alcoholic fermented milk","volume":"84","author":"Sudun","year":"2013","journal-title":"Anim Sci J"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib55","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1365-2672.1985.tb01473.x","article-title":"Production of ethanol from infant food formulas by common yeasts","volume":"58","author":"Bivin","year":"1985","journal-title":"J Appl Bacteriol"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib56","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1002\/ueg2.12062","article-title":"Gut fermentation syndrome: a systematic review of case reports","volume":"9","author":"Bayoumy","year":"2021","journal-title":"Unit Eur Gastroenterol J"},{"issue":"11","key":"10.1016\/j.bj.2023.100625_bib57","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1128\/JCM.01737-13","article-title":"beta-D-glucan testing is important for diagnosis of invasive fungal infections","volume":"51","author":"Theel","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib58","first-page":"344","article-title":"Circulating beta (1-3) glucan and immunoglobulin G subclass antibodies to Candida albicans cell wall antigens in patients with systemic candidiasis","volume":"11","author":"Kondori","year":"2004","journal-title":"Clin Diagn Lab Immunol"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib59","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1189\/jlb.0310139","article-title":"Endogenous PGE2 promotes the induction of human Th17 responses by fungal \u00df-glucan","volume":"88","author":"Gagliardi","year":"2010","journal-title":"J Leukoc Biol"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib60","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.4049\/jimmunol.169.7.3876","article-title":"The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte\/macrophage and neutrophil lineages","volume":"169","author":"Taylor","year":"2002","journal-title":"J Immunol"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib61","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1172\/JCI90562","article-title":"Intestinal fungi contribute to development of alcoholic liver disease","volume":"127","author":"Yang","year":"2017","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib62","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/s41401-022-00926-2","article-title":"Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation","volume":"44","author":"Wang","year":"2023","journal-title":"Acta Pharmacol Sin"},{"issue":"18","key":"10.1016\/j.bj.2023.100625_bib63","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.3390\/cells11182879","article-title":"Dectin-1 as a potential inflammatory biomarker for metabolic inflammation in adipose tissue of individuals with obesity","volume":"11","author":"Al Madhoun","year":"2022","journal-title":"Cells"},{"issue":"11","key":"10.1016\/j.bj.2023.100625_bib64","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1016\/j.celrep.2017.05.059","article-title":"Dectin-1 activation exacerbates obesity and insulin resistance in the absence of MyD88","volume":"19","author":"Castoldi","year":"2017","journal-title":"Cell Rep"},{"issue":"22","key":"10.1016\/j.bj.2023.100625_bib65","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202100819","article-title":"Yeast beta-glucan improves insulin sensitivity and hepatic lipid metabolism in mice humanized with obese type 2 diabetic gut microbiota","volume":"66","author":"Mitchelson","year":"2022","journal-title":"Mol Nutr Food Res"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib66","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.jceh.2022.06.008","article-title":"Hepatoprotective effects of aureobasidium pullulans derived beta 1,3-1,6 glucans in a murine model of non-alcoholic steatohepatitis","volume":"12","author":"Ikewaki","year":"2022","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.bj.2023.100625_bib67","doi-asserted-by":"crossref","DOI":"10.1038\/srep10457","article-title":"Oral administration of the Aureobasidium pullulans-derived beta-glucan effectively prevents the development of high fat diet-induced fatty liver in mice","volume":"5","author":"Aoki","year":"2015","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib68","first-page":"3","article-title":"An insoluble polysaccharide from the sclerotium of Poria cocos improves hyperglycemia, hyperlipidemia and hepatic steatosis in ob\/ob mice via modulation of gut microbiota","volume":"17","author":"Sun","year":"2019","journal-title":"Chin J Nat Med"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib69","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1128\/MMBR.00020-11","article-title":"Bacterial-fungal interactions: hyphens between agricultural, clinical, environmental, and food microbiologists","volume":"75","author":"Frey-Klett","year":"2011","journal-title":"Microbiol Mol Biol Rev"},{"issue":"6","key":"10.1016\/j.bj.2023.100625_bib70","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066019","article-title":"Archaea and fungi of the human gut microbiome: correlations with diet and bacterial residents","volume":"8","author":"Hoffmann","year":"2013","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib71","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00351-17","article-title":"High-fat diet changes fungal microbiomes and interkingdom relationships in the murine gut","volume":"2","author":"Heisel","year":"2017","journal-title":"mSphere"},{"issue":"22","key":"10.1016\/j.bj.2023.100625_bib72","doi-asserted-by":"crossref","first-page":"9066","DOI":"10.1073\/pnas.1219451110","article-title":"Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity","volume":"110","author":"Everard","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"10.1016\/j.bj.2023.100625_bib73","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3920\/BM2019.0056","article-title":"Saccharomyces boulardii Tht 500101 changes gut microbiota and ameliorates hyperglycaemia, dyslipidaemia, and liver inflammation in streptozotocin-diabetic mice","volume":"10","author":"Albuquerque","year":"2019","journal-title":"Benef Microbes"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041079","article-title":"Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity","volume":"7","author":"Gauffin Cano","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib75","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2192547","article-title":"Experimental diets dictate the metabolic benefits of probiotics in obesity","volume":"15","author":"Larsen","year":"2023","journal-title":"Gut Microb"},{"issue":"3","key":"10.1016\/j.bj.2023.100625_bib76","doi-asserted-by":"crossref","first-page":"e01011","DOI":"10.1128\/mBio.01011-14","article-title":"Saccharomyces boulardii administration changes gut microbiota and reduces hepatic steatosis, low-grade inflammation, and fat mass in obese and type 2 diabetic db\/db mice","volume":"5","author":"Everard","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.bj.2023.100625_bib77","article-title":"Saccharomyces boulardii ameliorates non-alcoholic steatohepatitis in mice induced by a methionine-choline-deficient diet through gut-liver Axis","volume":"13","author":"Yang","year":"2022","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.bj.2023.100625_bib78","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.3390\/nu13082512","article-title":"Effects of 60-day Saccharomyces boulardii and superoxide dismutase supplementation on body composition, hunger sensation, pro\/antioxidant ratio, inflammation and hormonal lipo-metabolic biomarkers in obese adults: a double-blind, placebo-controlled trial","volume":"13","author":"Rondanelli","year":"2021","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.bj.2023.100625_bib79","doi-asserted-by":"crossref","first-page":"658","DOI":"10.9721\/KJFST.2015.47.5.658","article-title":"The effect of rice with Aspergillus terreus on lipid metabolism in rats","volume":"47","author":"Jang","year":"2015","journal-title":"Kor J Food Sci Technol"},{"key":"10.1016\/j.bj.2023.100625_bib80","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jnutbio.2017.02.014","article-title":"Kefir alleviates obesity and hepatic steatosis in high-fat diet-fed mice by modulation of gut microbiota and mycobiota: targeted and untargeted community analysis with correlation of biomarkers","volume":"44","author":"Kim","year":"2017","journal-title":"J Nutr Biochem"},{"issue":"7","key":"10.1016\/j.bj.2023.100625_bib81","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1002\/mnfr.201100095","article-title":"Diet high in oat \u03b2-glucan activates the gut-hypothalamic (PYY\u2083\u208b\u2083\u2086-NPY) axis and increases satiety in diet-induced obesity in mice","volume":"55","author":"Huang","year":"2011","journal-title":"Mol Nutr Food Res"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib82","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3390\/nu13020527","article-title":"High \u03b2-glucan barley supplementation improves glucose tolerance by increasing GLP-1 secretion in diet-induced obesity mice","volume":"13","author":"Suzuki","year":"2021","journal-title":"Nutrients"},{"issue":"44","key":"10.1016\/j.bj.2023.100625_bib83","doi-asserted-by":"crossref","first-page":"9665","DOI":"10.1021\/acs.jafc.7b03782","article-title":"Orally administered baker's yeast \u03b2-glucan promotes glucose and lipid homeostasis in the livers of obesity and diabetes model mice","volume":"65","author":"Cao","year":"2017","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib84","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3797\/scipharm.ISP.2015.07","article-title":"Cholesterol-lowering effect of beta glucan extracted from Saccharomyces cerevisiae in rats","volume":"84","author":"Kusmiati","year":"2016","journal-title":"Sci Pharm"},{"issue":"22","key":"10.1016\/j.bj.2023.100625_bib85","doi-asserted-by":"crossref","first-page":"11664","DOI":"10.1039\/D2FO01167K","article-title":"Highland barley \u03b2-glucan alleviated western diet-induced non-alcoholic fatty liver disease via increasing energy expenditure and regulating bile acid metabolism in mice","volume":"13","author":"Liu","year":"2022","journal-title":"Food Funct"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib86","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1080\/19390211.2016.1207005","article-title":"Yeast \u03b2-glucan modulates inflammation and waist circumference in overweight and obese subjects","volume":"14","author":"Mosikanon","year":"2017","journal-title":"J Diet Suppl"},{"key":"10.1016\/j.bj.2023.100625_bib87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.nut.2017.05.002","article-title":"Effects of high \u03b2-glucan barley on visceral fat obesity in Japanese individuals: a randomized, double-blind study","volume":"42","author":"Aoe","year":"2017","journal-title":"Nutrition"},{"key":"10.1016\/j.bj.2023.100625_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115457","article-title":"Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitis","volume":"296","author":"Ye","year":"2022","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"10.1016\/j.bj.2023.100625_bib89","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jbiosc.2011.04.012","article-title":"Effects of cultural medium and conditions on the proliferation and hypoglycemic activity of Saccharomyces pastorianus no. 54","volume":"112","author":"Wu","year":"2011","journal-title":"J Biosci Bioeng"},{"issue":"14","key":"10.1016\/j.bj.2023.100625_bib90","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.3390\/molecules26144232","article-title":"Exploration of hypoglycemic activity of Saccharomyces pastorianus extract and evaluation of the molecular mechanisms","volume":"26","author":"Wu","year":"2021","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.bj.2023.100625_bib91","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2012.06.031","article-title":"Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome","volume":"143","author":"Vrieze","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bj.2023.100625_bib92","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.1089991","article-title":"Fecal microbiota transplantation reverses insulin resistance in type 2 diabetes: a randomized, controlled, prospective study","volume":"12","author":"Wu","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.bj.2023.100625_bib93","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.759306","article-title":"Effect of fecal microbiota transplantation on non-alcoholic fatty liver disease: a randomized clinical trial","volume":"12","author":"Xue","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"10.1016\/j.bj.2023.100625_bib94","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s40168-017-0373-4","article-title":"The gut mycobiome of the Human Microbiome Project healthy cohort","volume":"5","author":"Nash","year":"2017","journal-title":"Microbiome"}],"container-title":["Biomedical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417023000628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417023000628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T17:43:21Z","timestamp":1722275001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2319417023000628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":94,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S2319417023000628"],"URL":"https:\/\/doi.org\/10.1016\/j.bj.2023.100625","relation":{},"ISSN":["2319-4170"],"issn-type":[{"value":"2319-4170","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gut mycobiome in metabolic diseases: Mechanisms and clinical implication","name":"articletitle","label":"Article Title"},{"value":"Biomedical Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bj.2023.100625","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V. on behalf of Chang Gung University.","name":"copyright","label":"Copyright"}],"article-number":"100625"}}