{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:42:44Z","timestamp":1786740164452,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:00:00Z","timestamp":1762560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC 113-2314-B-182A-005"],"award-info":[{"award-number":["NSTC 113-2314-B-182A-005"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"Taiwan Ministry of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CORPG8P0731"],"award-info":[{"award-number":["CORPG8P0731"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Journal"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.bj.2025.100930","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T23:30:15Z","timestamp":1762903815000},"page":"100930","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Extracorporeal shockwave therapy ameliorates skin inflammation of imiquimod-induced psoriasis in mice"],"prefix":"10.1016","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7069-6993","authenticated-orcid":false,"given":"Shang-Hung","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Sheng","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Chun","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bj.2025.100930_bib1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1046\/j.1087-0024.2003.09102.x","article-title":"Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction","volume":"9","author":"Stern","year":"2004","journal-title":"J Invest Dermatol Symp Proc"},{"issue":"3","key":"10.1016\/j.bj.2025.100930_bib2","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/sj.jid.5701067","article-title":"Cellular genomic maps help dissect pathology in human skin disease","volume":"128","author":"Haider","year":"2008","journal-title":"J Invest Dermatol"},{"issue":"1","key":"10.1016\/j.bj.2025.100930_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/jid.2012.194","article-title":"The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings","volume":"133","author":"Martin","year":"2013","journal-title":"J Invest Dermatol"},{"issue":"10281","key":"10.1016\/j.bj.2025.100930_bib4","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.bj.2025.100930_bib5","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1172\/JCI59643","article-title":"Macrophage plasticity and polarization: in vivo veritas","volume":"122","author":"Sica","year":"2012","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.bj.2025.100930_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.immuni.2014.06.008","article-title":"Macrophage activation and polarization: nomenclature and experimental guidelines","volume":"41","author":"Murray","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.bj.2025.100930_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.867260","article-title":"The role of M1\/M2 macrophage polarization in rheumatoid arthritis synovitis","volume":"13","author":"Cutolo","year":"2022","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.bj.2025.100930_bib8","doi-asserted-by":"crossref","first-page":"520","DOI":"10.7150\/ijbs.8879","article-title":"Macrophage polarization in inflammatory diseases","volume":"10","author":"Liu","year":"2014","journal-title":"Int J Biol Sci"},{"issue":"3","key":"10.1016\/j.bj.2025.100930_bib9","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jdermsci.2018.05.009","article-title":"Treatment with TNF-alpha inhibitor rectifies M1 macrophage polarization from blood CD14+ monocytes in patients with psoriasis independent of STAT1 and IRF-1 activation","volume":"91","author":"Lin","year":"2018","journal-title":"J Dermatol Sci"},{"issue":"9","key":"10.1016\/j.bj.2025.100930_bib10","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1172\/JCI32282","article-title":"Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages","volume":"117","author":"Zaba","year":"2007","journal-title":"J Clin Invest"},{"issue":"7","key":"10.1016\/j.bj.2025.100930_bib11","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.3390\/pharmaceutics13071064","article-title":"Therapeutic development based on the immunopathogenic mechanisms of psoriasis","volume":"13","author":"Tseng","year":"2021","journal-title":"Pharmaceutics"},{"issue":"12","key":"10.1016\/j.bj.2025.100930_bib12","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11882-022-01047-w","article-title":"Biologics and small molecule inhibitors: an update in therapies for allergic and immunologic skin diseases","volume":"22","author":"Dodson","year":"2022","journal-title":"Curr Allergy Asthma Rep"},{"issue":"9","key":"10.1016\/j.bj.2025.100930_bib13","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.3390\/genes12091398","article-title":"Pharmacogenomics: an update on biologics and small-molecule drugs in the treatment of psoriasis","volume":"12","author":"Caputo","year":"2021","journal-title":"Genes"},{"issue":"11","key":"10.1016\/j.bj.2025.100930_bib14","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1177\/1759720X17735756","article-title":"Anti-interleukin and interleukin therapies for psoriasis: current evidence and clinical usefulness","volume":"9","author":"Tsai","year":"2017","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"10.1016\/j.bj.2025.100930_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1264842","article-title":"Novel potential pharmacological applications of dimethyl fumarate-an overview and update","volume":"14","author":"Bresciani","year":"2023","journal-title":"Front Pharmacol"},{"issue":"6","key":"10.1016\/j.bj.2025.100930_bib16","first-page":"631","article-title":"Extracorporeal shock wave therapy ameliorates cyclophosphamide-induced rat acute interstitial cystitis though inhibiting inflammation and oxidative stress-in vitro and in vivo experiment studies","volume":"6","author":"Chen","year":"2014","journal-title":"Am J Transl Res"},{"issue":"2","key":"10.1016\/j.bj.2025.100930_bib17","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1177\/03635465030310021901","article-title":"Shock wave application for chronic plantar fasciitis in running athletes. A prospective, randomized, placebo-controlled trial","volume":"31","author":"Rompe","year":"2003","journal-title":"Am J Sports Med"},{"issue":"4","key":"10.1016\/j.bj.2025.100930_bib18","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1524-475X.2009.00504.x","article-title":"Extracorporeal shock-wave therapy enhanced wound healing via increasing topical blood perfusion and tissue regeneration in a rat model of STZ-induced diabetes","volume":"17","author":"Kuo","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"9","key":"10.1016\/j.bj.2025.100930_bib19","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.molmed.2013.05.005","article-title":"Mechanotherapy: revisiting physical therapy and recruiting mechanobiology for a new era in medicine","volume":"19","author":"Huang","year":"2013","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.bj.2025.100930_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9915877","article-title":"Extracorporeal shockwave therapy modulates the expressions of proinflammatory cytokines IL33 and IL17A, and their receptors ST2 and IL17RA, within the articular cartilage in early avascular necrosis of the femoral head in a rat model","volume":"2021","author":"Cheng","year":"2021","journal-title":"Mediators Inflamm"},{"issue":"15","key":"10.1016\/j.bj.2025.100930_bib21","doi-asserted-by":"crossref","first-page":"7844","DOI":"10.3390\/ijms22157844","article-title":"Low intensity shockwave treatment modulates macrophage functions beneficial to healing chronic wounds","volume":"22","author":"Holsapple","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"Pt B","key":"10.1016\/j.bj.2025.100930_bib22","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ijsu.2015.07.719","article-title":"Effect of shock waves on macrophages: a possible role in tissue regeneration and remodeling","volume":"24","author":"Sukubo","year":"2015","journal-title":"Int J Surg"},{"issue":"6","key":"10.1016\/j.bj.2025.100930_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol"},{"issue":"12","key":"10.1016\/j.bj.2025.100930_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/iid3.734","article-title":"Etanercept alleviates psoriasis by reducing the Th17\/Treg ratio and promoting M2 polarization of macrophages","volume":"10","author":"Li","year":"2022","journal-title":"Immun Inflamm Dis"},{"issue":"9","key":"10.1016\/j.bj.2025.100930_bib25","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.4049\/jimmunol.0802999","article-title":"Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23\/IL-17 axis","volume":"182","author":"van der Fits","year":"2009","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.bj.2025.100930_bib26","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000368351","article-title":"Extracorporeal shock wave therapy for injection site panniculitis in multiple sclerosis patients","volume":"230","author":"Stieger","year":"2015","journal-title":"Dermatology"},{"issue":"8","key":"10.1016\/j.bj.2025.100930_bib27","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1172\/JCI29441","article-title":"Misbehaving macrophages in the pathogenesis of psoriasis","volume":"116","author":"Clark","year":"2006","journal-title":"J Clin Investig"},{"issue":"4","key":"10.1016\/j.bj.2025.100930_bib28","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/j.1365-2133.2010.10129.x","article-title":"Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie 2 mice","volume":"164","author":"Ward","year":"2011","journal-title":"Br J Dermatol"},{"issue":"8","key":"10.1016\/j.bj.2025.100930_bib29","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1172\/JCI27180","article-title":"Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation","volume":"116","author":"Wang","year":"2006","journal-title":"J Clin Invest"},{"issue":"4","key":"10.1016\/j.bj.2025.100930_bib30","doi-asserted-by":"crossref","DOI":"10.1111\/sji.12946","article-title":"The TNF\/IL-23\/IL-17 axis-head-to-head trials comparing different biologics in psoriasis treatment","volume":"92","author":"Ten Bergen","year":"2020","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.bj.2025.100930_bib31","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2147\/IJNRD.S389219","article-title":"Low-intensity extracorporeal shockwave therapy (LI-ESWT) in renal diseases: a review of animal and human studies","volume":"16","author":"Skov-Jeppesen","year":"2023","journal-title":"Int J Nephrol Renovasc Dis"},{"issue":"5","key":"10.1016\/j.bj.2025.100930_bib32","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jaci.2013.05.036","article-title":"Infliximab induces downregulation of the IL-12\/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages","volume":"132","author":"Brunner","year":"2013","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.bj.2025.100930_bib33","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s12016-018-8668-1","article-title":"Psoriasis: from pathogenesis to targeted therapies","volume":"54","author":"Conrad","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"issue":"3","key":"10.1016\/j.bj.2025.100930_bib34","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s12016-018-8702-3","article-title":"The immunologic role of IL-17 in psoriasis and psoriatic arthritis pathogenesis","volume":"55","author":"Blauvelt","year":"2018","journal-title":"Clin Rev Allergy Immunol"}],"container-title":["Biomedical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417025001040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417025001040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:50:53Z","timestamp":1786737053000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2319417025001040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2319417025001040"],"URL":"https:\/\/doi.org\/10.1016\/j.bj.2025.100930","relation":{},"ISSN":["2319-4170"],"issn-type":[{"value":"2319-4170","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extracorporeal shockwave therapy ameliorates skin inflammation of imiquimod-induced psoriasis in mice","name":"articletitle","label":"Article Title"},{"value":"Biomedical Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bj.2025.100930","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V. on behalf of Chang Gung University.","name":"copyright","label":"Copyright"}],"article-number":"100930"}}