{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T21:06:26Z","timestamp":1785618386529,"version":"3.56.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"National Institutes of Health \u2013 National Heart, Lung, and Blood Institute"},{"DOI":"10.13039\/100000002","name":"NIH-NHLBI)","doi-asserted-by":"publisher","award":["1R34HL123438"],"award-info":[{"award-number":["1R34HL123438"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.bja.2018.04.021","type":"journal-article","created":{"date-parts":[[2018,6,2]],"date-time":"2018-06-02T00:47:15Z","timestamp":1527900435000},"page":"899-908","source":"Crossref","is-referenced-by-count":101,"title":["Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients"],"prefix":"10.1016","volume":"121","author":[{"given":"L.","family":"Ball","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.N.T.","family":"Hemmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Serpa Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Bluth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Canet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hiesmayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.W.","family":"Hollmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.H.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.F.","family":"Vidal Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Putensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Severgnini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Wrigge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Gama de Abreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Pelosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bja.2018.04.021_bib1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/ACO.0000000000000267","article-title":"Preoxygenation and intraoperative ventilation strategies in obese patients: a comprehensive review","volume":"29","author":"Shah","year":"2016","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1399-6576.1976.tb05055.x","article-title":"Oxygen transport and venous admixture in the extremely obese. Influence of anaesthesia and artificial ventilation with and without positive end-expiratory pressure","volume":"20","author":"Santesson","year":"1976","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.bja.2018.04.021_bib3","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/ACO.0000000000000337","article-title":"The obese patient undergoing nonbariatric surgery","volume":"29","author":"Bluth","year":"2016","journal-title":"Curr Opin Anesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib4","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1093\/bja\/aei231","article-title":"Pre-oxygenation in the obese patient: effects of position on tolerance to apnoea","volume":"95","author":"Altermatt","year":"2005","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2018.04.021_bib5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s13054-017-1641-1","article-title":"Mechanical ventilation in obese ICU patients: from intubation to extubation","volume":"21","author":"De Jong","year":"2017","journal-title":"Crit Care"},{"key":"10.1016\/j.bja.2018.04.021_bib6","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s00268-006-0305-0","article-title":"Postoperative complications in obese and nonobese patients","volume":"31","author":"Bamgbade","year":"2007","journal-title":"World J Surg"},{"key":"10.1016\/j.bja.2018.04.021_bib7","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1097\/EJA.0000000000000646","article-title":"Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS \u2013 an observational study in 29 countries","volume":"34","author":"LAS VEGAS","year":"2017","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib8","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1097\/00000539-200212000-00060","article-title":"Morbid obesity and postoperative pulmonary atelectasis: an underestimated problem","volume":"95","author":"Eichenberger","year":"2002","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2018.04.021_bib9","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1097\/ALN.0b013e3181b87edb","article-title":"Prevention of atelectasis in morbidly obese patients during general anesthesia and paralysis: a computerized tomography study","volume":"111","author":"Reinius","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib10","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1213\/ANE.0b013e3181ba7945","article-title":"Intraoperative ventilatory strategies for prevention of pulmonary atelectasis in obese patients undergoing laparoscopic bariatric surgery","volume":"109","author":"Talab","year":"2009","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2018.04.021_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/aas.12588","article-title":"Preserved oxygenation in obese patients receiving protective ventilation during laparoscopic surgery: a randomized controlled study","volume":"60","author":"Edmark","year":"2016","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.bja.2018.04.021_bib12","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1097\/ALN.0b013e3181fc640a","article-title":"Intraoperative recruitment maneuver reverses detrimental pneumoperitoneum-induced respiratory effects in healthy weight and obese patients undergoing laparoscopy","volume":"113","author":"Futier","year":"2010","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib13","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1111\/j.1365-2044.2012.07218.x","article-title":"A\u00a0multicentre observational study of intra-operative ventilatory management during general anaesthesia: tidal volumes and relation to body weight","volume":"67","author":"Jaber","year":"2012","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bja.2018.04.021_bib14","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1097\/ALN.0000000000000754","article-title":"Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers","volume":"123","author":"G\u00fcldner","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/ALN.0000000000000706","article-title":"Protective versus conventional ventilation for surgery: a systematic review and individual patient data meta-analysis","volume":"123","author":"Serpa Neto","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib16","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1111\/obr.12274","article-title":"Intraoperative mechanical ventilation strategies for obese patients: a systematic review and network meta-analysis: mechanical ventilation for obese patient","volume":"16","author":"Wang","year":"2015","journal-title":"Obes Rev"},{"key":"10.1016\/j.bja.2018.04.021_bib17","article-title":"Overview of proposed LAS VEGAS sub-studies and sub-analyses","year":"2015","journal-title":"ESA Clin Trial Netw"},{"key":"10.1016\/j.bja.2018.04.021_bib18","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1097\/ALN.0b013e3181fc6e0a","article-title":"Prediction of postoperative pulmonary complications in a population-based surgical cohort","volume":"113","author":"Canet","year":"2010","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib19","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12871-015-0032-x","article-title":"Perioperative lung protective ventilation in obese patients","volume":"15","author":"Fernandez-Bustamante","year":"2015","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib20","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0895-4356(01)00372-9","article-title":"Logistic regression in the medical literature: standards for use and reporting, with particular attention to one medical domain","volume":"54","author":"Bagley","year":"2001","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.bja.2018.04.021_bib21","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1097\/CCM.0000000000001670","article-title":"The fragility index in multicenter randomized controlled critical care trials","volume":"44","author":"Ridgeon","year":"2016","journal-title":"Crit Care Med"},{"key":"10.1016\/j.bja.2018.04.021_bib22","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.jamcollsurg.2007.02.070","article-title":"Multivariable predictors of postoperative respiratory failure after general and vascular surgery: results from the patient safety in surgery study","volume":"204","author":"Johnson","year":"2007","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.bja.2018.04.021_bib23","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/EJA.0000000000000223","article-title":"Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: a prospective, observational study","volume":"32","author":"Canet","year":"2015","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib24","doi-asserted-by":"crossref","first-page":"581","DOI":"10.7326\/0003-4819-144-8-200604180-00009","article-title":"Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians","volume":"144","author":"Smetana","year":"2006","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.bja.2018.04.021_bib25","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1378\/chest.12-2905","article-title":"Sleep-disordered breathing and postoperative outcomes after elective surgery: analysis of the nationwide inpatient sample","volume":"144","author":"Mokhlesi","year":"2013","journal-title":"Chest"},{"key":"10.1016\/j.bja.2018.04.021_bib26","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/bja\/aes338","article-title":"Ventilation strategies in obese patients undergoing surgery: a quantitative systematic review and meta-analysis","volume":"109","author":"Aldenkortt","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2018.04.021_bib27","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/SLA.0000000000001499","article-title":"Differential effects of intraoperative positive end-expiratory pressure (PEEP) on respiratory outcome in major abdominal surgery versus craniotomy","volume":"264","author":"de Jong","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.bja.2018.04.021_bib28","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1056\/NEJMoa1301082","article-title":"A\u00a0trial of intraoperative low-tidal-volume ventilation in abdominal surgery","volume":"369","author":"Futier","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.bja.2018.04.021_bib29","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0140-6736(14)60416-5","article-title":"High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial","volume":"384","author":"Hemmes","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2018.04.021_bib30","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/ALN.0000000000000549","article-title":"Role of recruitment maneuvers for lung-protective ventilation in the operating room remains unclear","volume":"122","author":"Treschan","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib31","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.bpa.2015.08.003","article-title":"Modes of mechanical ventilation for the operating room","volume":"29","author":"Ball","year":"2015","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib32","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1213\/ANE.0000000000001173","article-title":"Fast versus slow recruitment maneuver at different degrees of acute lung inflammation induced by experimental sepsis","volume":"122","author":"Santos","year":"2016","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2018.04.021_bib33","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/EJA.0000000000000118","volume":"32","author":"Jammer","year":"2015","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib34","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1001\/jamasurg.2016.4065","article-title":"Postoperative pulmonary complications, early mortality, and hospital stay following noncardiothoracic surgery: a multicenter study by the perioperative research network investigators","volume":"152","author":"Fernandez-Bustamante","year":"2017","journal-title":"JAMA Surg"},{"key":"10.1016\/j.bja.2018.04.021_bib35","article-title":"Continuous positive airway pressure (CPAP) during the postoperative period for prevention of postoperative morbidity and mortality following major abdominal surgery","volume":"8","author":"Ireland","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.bja.2018.04.021_bib36","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/s13063-017-1929-0","article-title":"Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial","volume":"18","author":"Bluth","year":"2017","journal-title":"Trials"},{"key":"10.1016\/j.bja.2018.04.021_bib37","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/bja\/aex192","article-title":"Individualized positive end-expiratory pressure in obese patients during general anaesthesia: a randomized controlled clinical trial using electrical impedance tomography","volume":"119","author":"Nestler","year":"2017","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2018.04.021_bib38","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/ACO.0000000000000281","article-title":"Perioperative opioids aggravate obstructive breathing in sleep apnea syndrome: mechanisms and alternative anesthesia strategies","volume":"29","author":"Mulier","year":"2016","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.bja.2018.04.021_bib39","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/01.anes.0000270723.30772.da","article-title":"Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial","volume":"107","author":"Myles","year":"2007","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2018.04.021_bib40","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1378\/chest.15-1777","article-title":"CPAP in the perioperative setting: evidence of support","volume":"149","author":"Chung","year":"2016","journal-title":"Chest"},{"key":"10.1016\/j.bja.2018.04.021_bib41","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1381\/096089202320995510","article-title":"Positioning the morbidly obese patient for anesthesia","volume":"12","author":"Brodsky","year":"2002","journal-title":"Obes Surg"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091218303283?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091218303283?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T21:56:16Z","timestamp":1569880576000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091218303283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0007091218303283"],"URL":"https:\/\/doi.org\/10.1016\/j.bja.2018.04.021","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}