{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:55:10Z","timestamp":1792857310078,"version":"4.5.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009068","name":"University of Bern","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009068","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005688","name":"Gottfried und Julia Bangerter-Rhyner-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005688","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjanaesthesia.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.bja.2022.12.026","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T17:12:29Z","timestamp":1678209149000},"page":"536-545","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["Five commercial \u2018depth of anaesthesia\u2019 monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals"],"prefix":"10.1016","volume":"130","author":[{"given":"Darren","family":"Hight","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Kreuzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesar","family":"Ugen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"St\u00fcber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Sleigh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiko A.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bja.2022.12.026_bib1","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1097\/ALN.0b013e3182390396","article-title":"Depth of anesthesia: perhaps the patient isn\u2019t a submarine","volume":"115","author":"Sleigh","year":"2011","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib2","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1097\/ALN.0b013e31826904a6","article-title":"Prevention of intraoperative awareness with explicit recall in an unselected surgical population: a randomized comparative effectiveness trial","volume":"117","author":"Mashour","year":"2012","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib3","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1213\/ANE.0b013e3181b8b6ca","article-title":"Posttraumatic stress disorder in aware patients from the B-aware trial","volume":"110","author":"Leslie","year":"2010","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2022.12.026_bib4","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/S0140-6736(04)16300-9","article-title":"Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial","volume":"363","author":"Myles","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2022.12.026_bib5","first-page":"3664","article-title":"Bispectral index monitoring prevent awareness during total intravenous anesthesia: a prospective, randomized, double-blinded, multi-center controlled trial","volume":"124","author":"Zhang","year":"2011","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.bja.2022.12.026_bib6","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1056\/NEJMoa1100403","article-title":"Prevention of intraoperative awareness in a high-risk surgical population","volume":"365","author":"Avidan","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.bja.2022.12.026_bib7","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1213\/ANE.0000000000000989","article-title":"Intraoperative electroencephalogram suppression predicts postoperative delirium","volume":"122","author":"Fritz","year":"2016","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2022.12.026_bib8","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1001\/jama.2018.22005","article-title":"Effect of electroencephalography-guided anesthetic administration on postoperative delirium among older adults undergoing major surgery","volume":"321","author":"Wildes","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.bja.2022.12.026_bib9","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1016\/S0140-6736(19)32315-3","article-title":"Anaesthetic depth and complications after major surgery: an international, randomised controlled trial","volume":"394","author":"Short","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2022.12.026_bib10","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/bja\/aeg188","article-title":"Detection of awareness in surgical patients with EEG-based indices \u2014 bispectral index and patient state index","volume":"91","author":"Schneider","year":"2003","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00008506-200201000-00002","article-title":"Bispectral index (BIS) may not predict awareness reaction to intubation in surgical patients","volume":"14","author":"Schneider","year":"2002","journal-title":"J\u00a0Neurosurg Anesthesiol"},{"key":"10.1016\/j.bja.2022.12.026_bib12","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/ALN.0000000000001479","article-title":"Incidence of connected consciousness after tracheal intubation","volume":"126","author":"Sanders","year":"2017","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib13","doi-asserted-by":"crossref","first-page":"e217","DOI":"10.1016\/j.bja.2022.04.010","article-title":"Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study","volume":"130","author":"Lennertz","year":"2023","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2021.110325","article-title":"The influence of age on EEG-based anaesthesia indices","volume":"73","author":"Obert","year":"2021","journal-title":"J\u00a0Clin Anesth"},{"key":"10.1016\/j.bja.2022.12.026_bib15","doi-asserted-by":"crossref","first-page":"i95","DOI":"10.1093\/bja\/aev072","article-title":"Response of bispectral index to neuromuscular block in awake volunteers","volume":"115","author":"Schuller","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib16","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/ACO.0b013e3283304032","article-title":"Processed electroencephalogram in depth of anesthesia monitoring","volume":"22","author":"Palanca","year":"2009","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.bja.2022.12.026_bib17","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1097\/ALN.0b013e3182395dcb","article-title":"Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial","volume":"115","author":"Whitlock","year":"2011","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib18","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1093\/bja\/aew089","article-title":"Response of bispectral index to neuromuscular block in awake volunteers","volume":"116","author":"Short","year":"2016","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib19","first-page":"2","article-title":"Beware the drug titration paradox. Comment on Br J Anaesth 2021; 127: 704\u201312","author":"Schnider","year":"2022","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib20","doi-asserted-by":"crossref","first-page":"E1142","DOI":"10.1073\/pnas.1221180110","article-title":"Electroencephalogram signatures of loss and recovery of consciousness from propofol","volume":"110","author":"Purdon","year":"2013","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.bja.2022.12.026_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106291","article-title":"Electroencephalographic variation during end maintenance and emergence from surgical anesthesia","volume":"9","author":"Chander","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bja.2022.12.026_bib22","first-page":"1","article-title":"Association of electroencephalogram trajectories during emergence from anaesthesia with delirium in the post-anaesthesia care unit: an early sign of postoperative complications","volume":"13","author":"Hesse","year":"2018","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib23","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/ALN.0000000000000841","article-title":"Clinical Electroencephalography for anesthesiologists: Part I. Background and basic signatures","volume":"123","author":"Purdon","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib24","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1007\/s12630-020-01820-3","article-title":"An updated introduction to electroencephalogram-based brain monitoring during intended general anesthesia","volume":"67","author":"Hight","year":"2020","journal-title":"Can J Anesth"},{"key":"10.1016\/j.bja.2022.12.026_bib25","first-page":"1","article-title":"Frontal electroencephalogram reveals emergence-like brain activity occurring during transition periods in cardiac surgery","volume":"125","author":"Kaiser","year":"2020","journal-title":"Br J Anaesth [Internet]"},{"key":"10.1016\/j.bja.2022.12.026_bib26","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1213\/01.ane.0000249045.52690.e8","article-title":"Construction of the electroencephalogram player: a device to present electroencephalogram data to electroencephalogram-based anesthesia monitors","volume":"104","author":"Kreuzer","year":"2007","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2022.12.026_bib27","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1213\/ANE.0b013e31825801ea","article-title":"Time delay of monitors of the hypnotic component of anesthesia","volume":"115","author":"Kreuzer","year":"2012","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2022.12.026_bib28","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/s12630-018-1085-3","article-title":"Prevalence of discordant elevations of state entropy and bispectral index in patients at amnestic sevoflurane concentrations: a historical cohort study","volume":"65","author":"Epstein","year":"2018","journal-title":"Can J Anesth"},{"key":"10.1016\/j.bja.2022.12.026_bib29","doi-asserted-by":"crossref","first-page":"563","DOI":"10.23736\/S0375-9393.17.11262-9","article-title":"Monitoring depth of sedation: evaluating the agreement between the bispectral index, qCON and the entropy module\u2019s state entropy during flexible bronchoscopy","volume":"83","author":"M\u00fcller","year":"2017","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.bja.2022.12.026_bib30","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1097\/ALN.0000000000001759","article-title":"Investigation of Slow-wave activity saturation during surgical anesthesia reveals a signature of neural inertia in humans","volume":"127","author":"Warnaby","year":"2017","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib31","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/ALN.0000000000002480","article-title":"Triple-low alerts do not reduce mortality: a real-time randomized trial","volume":"130","author":"Sessler","year":"2019","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib32","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.bja.2021.08.008","article-title":"The quagmire of postoperative delirium: does dose matter?","volume":"127","author":"Gaskell","year":"2021","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib33","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1213\/ANE.0000000000004653","article-title":"Of parachutes, speedometers, and EEG: what evidence do we need to use devices and monitors?","volume":"130","author":"Berger","year":"2020","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2022.12.026_bib34","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1093\/bja\/aex170","article-title":"Frontal alpha-delta EEG does not preclude volitional response during anaesthesia: prospective cohort study of the isolated forearm technique","volume":"119","author":"Gaskell","year":"2017","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2022.12.026_bib35","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1097\/ALN.0b013e31829103f5","article-title":"Disruption of frontal\u2013parietal communication by ketamine, propofol, and sevoflurane","volume":"118","author":"Lee","year":"2013","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2022.12.026_bib36","first-page":"1","article-title":"Role of electroencephalogram oscillations and the spectrogram in monitoring anaesthesia","volume":"20","author":"Kim","year":"2020","journal-title":"BJA Educ"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091223000260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091223000260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T19:05:02Z","timestamp":1757790302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091223000260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S0007091223000260"],"URL":"https:\/\/doi.org\/10.1016\/j.bja.2022.12.026","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Five commercial \u2018depth of anaesthesia\u2019 monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals","name":"articletitle","label":"Article Title"},{"value":"British Journal of Anaesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bja.2022.12.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 British Journal of Anaesthesia. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}