{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:03:47Z","timestamp":1793747027415,"version":"4.6.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016240","name":"Nederlandse Vereniging voor Anesthesiologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016240","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjanaesthesia.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.bja.2024.02.011","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T21:46:10Z","timestamp":1710193570000},"page":"1419-1426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Influence of nitrous oxide added to general anaesthesia on postoperative mortality and morbidity: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9426-2903","authenticated-orcid":false,"given":"Jasper M.","family":"Kampman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim Y.Q.","family":"Plasmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Hermanides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8248-0244","authenticated-orcid":false,"given":"Markus W.","family":"Hollmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6959-149X","authenticated-orcid":false,"given":"Sjoerd","family":"Repping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1305-1846","authenticated-orcid":false,"given":"Nicolaas H.","family":"Sperna Weiland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bja.2024.02.011_bib1","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/S0140-6736(21)01787-6","article-title":"The 2021 report of the Lancet Countdown on health and climate change: code red for a healthy future","volume":"398","author":"Romanello","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2024.02.011_bib2","doi-asserted-by":"crossref","DOI":"10.1088\/1748-9326\/ab19e1","article-title":"International comparison of health care carbon footprints","volume":"14","author":"Pichler","year":"2019","journal-title":"Environ Res Lett"},{"key":"10.1016\/j.bja.2024.02.011_bib3","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/S0140-6736(22)01540-9","article-title":"The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels","volume":"400","author":"Romanello","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2024.02.011_bib4","doi-asserted-by":"crossref","first-page":"e381","DOI":"10.1016\/S2542-5196(17)30162-6","article-title":"The impact of surgery on global climate: a carbon footprinting study of operating theatres in three health systems","volume":"1","author":"MacNeill","year":"2017","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.bja.2024.02.011_bib5","doi-asserted-by":"crossref","first-page":"o1301","DOI":"10.1136\/bmj.o1301","article-title":"Inhaled anaesthesia and analgesia contribute to climate change","volume":"377","author":"Sherman","year":"2022","journal-title":"BMJ"},{"key":"10.1016\/j.bja.2024.02.011_bib6","doi-asserted-by":"crossref","first-page":"e622","DOI":"10.1016\/S2542-5196(23)00084-0","article-title":"Assessing the potential climate impact of anaesthetic gases","volume":"7","author":"Sulbaek Andersen","year":"2023","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.bja.2024.02.011_bib7","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1038\/s41591-023-02351-2","article-title":"Fair pathways to net-zero healthcare","volume":"29","author":"Bhopal","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.bja.2024.02.011_bib8","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/S0140-6736(14)60893-X","article-title":"The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial","volume":"384","author":"Myles","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.bja.2024.02.011_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD008984.pub2","article-title":"Nitrous oxide-based techniques versus nitrous oxide-free techniques for general anaesthesia","author":"Sun","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.bja.2024.02.011_bib10","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1093\/bja\/aew066","article-title":"Standardizing end points in perioperative trials: towards a core and extended outcome set","volume":"116","author":"Myles","year":"2016","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.02.011_bib11","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.bja.2024.02.011_bib12","series-title":"Cochrane Handbook for systematic reviews of Interventions","article-title":"Chapter 8: Assessing risk of bias in a randomized trial","author":"Higgins","year":"2023"},{"key":"10.1016\/j.bja.2024.02.011_bib13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.bja.2024.02.011_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/bimj.201900036","article-title":"Meta-analysis of the difference of medians","volume":"62","author":"McGrath","year":"2020","journal-title":"Biom J"},{"key":"10.1016\/j.bja.2024.02.011_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/01.anes.0000270723.30772.da","article-title":"Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial","volume":"107","author":"Myles","year":"2007","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.02.011_bib16","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/bja\/aet416","article-title":"Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis","volume":"112","author":"Imberger","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.02.011_bib17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1365-2044.2010.06249.x","article-title":"Association between nitrous oxide and the incidence of postoperative nausea and vomiting in adults: a systematic review and meta-analysis","volume":"65","author":"Fern\u00e1ndez-Guisasola","year":"2010","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bja.2024.02.011_bib18","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1097\/ALN.0000000000002134","article-title":"Positive end-expiratory pressure alone minimizes atelectasis formation in nonabdominal surgery: a randomized controlled trial","volume":"128","author":"\u00d6stberg","year":"2018","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.02.011_bib19","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/ALN.0000000000004497","article-title":"Postoperative pulmonary complications in the ENIGMA II Trial: a post hoc analysis","volume":"138","author":"Peyton","year":"2023","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.02.011_bib20","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1056\/NEJMoa032196","article-title":"A\u00a0factorial trial of six interventions for the prevention of postoperative nausea and vomiting","volume":"350","author":"Apfel","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.bja.2024.02.011_bib21","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.20f13681","article-title":"Mean difference, standardized mean difference (SMD), and their use in meta-analysis: as simple as it gets","volume":"81","author":"Andrade","year":"2020","journal-title":"J\u00a0Clin Psychiatry"},{"key":"10.1016\/j.bja.2024.02.011_bib22","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/ALN.0b013e3181870a17","article-title":"Biologic effects of nitrous oxide: a mechanistic and toxicologic review","volume":"109","author":"Sanders","year":"2008","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.02.011_bib23","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.bja.2019.01.023","article-title":"European Society of Anaesthesiology Task Force on nitrous oxide: a narrative review of its role in clinical practice","volume":"122","author":"Buhre","year":"2019","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.02.011_bib24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.56126\/74.4.24","article-title":"BeSARPP (Belgian Society of Anesthesiology, Resuscitation, Perioperative medicine and Pain management) recommendations on responsible and sustainable use of inhaled anesthetics: NO time TO WASTE","volume":"74","author":"Hendrickx","year":"2023","journal-title":"Acta Anaesth Bel"},{"key":"10.1016\/j.bja.2024.02.011_bib25","doi-asserted-by":"crossref","unstructured":"Gonzalez-Pizarro P, Brazzi L, Koch S, et\u00a0al. European Society of Anaesthesiology and Intensive Care consensus document on sustainability: 4 scopes to achieve a more sustainable practice. Eur J Anaesthesiol Adv Access Published January 19, 2024, https:\/\/doi.org\/10.1097\/EJA.0000000000001942.","DOI":"10.1097\/EJA.0000000000001942"},{"key":"10.1016\/j.bja.2024.02.011_bib26","doi-asserted-by":"crossref","DOI":"10.1097\/EA9.0000000000000025","article-title":"Environmental sustainability in the operating room: a worldwide survey among anaesthesiologists","volume":"2","author":"Gonzalez-Pizarro","year":"2023","journal-title":"Eur J Anaesthesiol Intensive Care"},{"key":"10.1016\/j.bja.2024.02.011_bib27","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/aas.12165","article-title":"Current use of nitrous oxide in public hospitals in Scandinavian countries","volume":"57","author":"Husum","year":"2013","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.bja.2024.02.011_bib28","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/bja\/aeu313","article-title":"5th National Audit Project (NAP5) on accidental awareness during general anaesthesia: summary of main findings and risk factors","volume":"113","author":"Pandit","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.02.011_bib29","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.1016\/j.bja.2021.10.021","article-title":"Discrepancy between procurement and clinical use of nitrous oxide: waste not, want not","volume":"128","author":"Seglenieks","year":"2022","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.02.011_bib30","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/anae.16211","article-title":"The Nitrous Oxide Project: assessment of advocacy and national directives to deliver mitigation of anaesthetic nitrous oxide","volume":"79","author":"Chakera","year":"2024","journal-title":"Anaesthesia"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091224000734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091224000734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T02:13:35Z","timestamp":1732068815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091224000734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0007091224000734"],"URL":"https:\/\/doi.org\/10.1016\/j.bja.2024.02.011","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of nitrous oxide added to general anaesthesia on postoperative mortality and morbidity: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"British Journal of Anaesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bja.2024.02.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of British Journal of Anaesthesia.","name":"copyright","label":"Copyright"}]}}