{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:40:44Z","timestamp":1787161244884,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M752246"],"award-info":[{"award-number":["2024M752246"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82401502"],"award-info":[{"award-number":["82401502"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Provincial Science and Technology Support Program","doi-asserted-by":"publisher","award":["2023NSFSC1583"],"award-info":[{"award-number":["2023NSFSC1583"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjanaesthesia.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.bja.2024.10.016","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T01:12:49Z","timestamp":1733965969000},"page":"453-460","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Intraoperative dexmedetomidine and acute kidney injury in paediatric noncardiac surgery: a retrospective propensity score-matched analysis"],"prefix":"10.1016","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-3652","authenticated-orcid":false,"given":"Rong","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2349-1559","authenticated-orcid":false,"given":"Xiaoya","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuehan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1743-078X","authenticated-orcid":false,"given":"Yunxia","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bja.2024.10.016_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/ALN.0000000000004057","article-title":"Intraoperative hypotension and acute kidney injury after noncardiac surgery in infants and children: a retrospective cohort analysis","volume":"136","author":"Schacham","year":"2022","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.10.016_bib2","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1213\/ANE.0000000000005069","article-title":"Acute kidney injury and outcomes in children undergoing noncardiac surgery: a propensity-matched analysis","volume":"132","author":"Wingert","year":"2021","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bja.2024.10.016_bib3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.bja.2021.06.045","article-title":"Renal tissue desaturation and acute kidney injury in infant cardiac surgery: a prospective propensity score-matched cohort study","volume":"127","author":"Zhang","year":"2021","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.10.016_bib4","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1097\/CCM.0b013e31821201d3","article-title":"Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study","volume":"39","author":"Li","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.bja.2024.10.016_bib5","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000480358","article-title":"Independent risk factors and 2-year outcomes of acute kidney injury after surgery for congenital heart disease","volume":"46","author":"Hirano","year":"2017","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.bja.2024.10.016_bib6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1611391","article-title":"Epidemiology of acute kidney injury in critically ill children and young adults","volume":"376","author":"Kaddourah","year":"2017","journal-title":"New Engl J Med"},{"key":"10.1016\/j.bja.2024.10.016_bib7","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1111\/anae.14227","article-title":"Pharmacological interventions for protecting renal function after cardiac surgery: a Bayesian network meta-analysis of comparative effectiveness","volume":"73","author":"Kim","year":"2018","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bja.2024.10.016_bib8","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s10157-019-01706-9","article-title":"Pharmacological interventions for the prevention of acute kidney injury after pediatric cardiac surgery: a network meta-analysis","volume":"23","author":"Bellos","year":"2019","journal-title":"Clin Exp Nephrol"},{"key":"10.1016\/j.bja.2024.10.016_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.4097\/kja.19259","article-title":"Dexmedetomidine: present and future directions","volume":"72","author":"Lee","year":"2019","journal-title":"Korean J Anesthesiol"},{"key":"10.1016\/j.bja.2024.10.016_bib10","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1080\/0886022X.2022.2097923","article-title":"Effect of dexmedetomidine for prevention of acute kidney injury after cardiac surgery: an updated systematic review and meta-analysis","volume":"44","author":"Liu","year":"2022","journal-title":"Ren Fail"},{"key":"10.1016\/j.bja.2024.10.016_bib11","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1053\/j.jvca.2019.09.011","article-title":"Effect of dexmedetomidine on cardiac surgery-associated acute kidney injury: a meta-analysis with trial sequential analysis of randomized controlled trials","volume":"34","author":"Peng","year":"2020","journal-title":"J\u00a0Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.bja.2024.10.016_bib12","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jclinane.2017.03.053","article-title":"The effect of dexmedetomidine on renal function in patients undergoing cardiac valve replacement under cardiopulmonary bypass: a double-blind randomized controlled trial","volume":"40","author":"Zhai","year":"2017","journal-title":"J\u00a0Clin Anesth"},{"key":"10.1016\/j.bja.2024.10.016_bib13","article-title":"Dexmedetomidine and acute kidney injury after non-cardiac surgery: a meta-analysis with trial sequential analysis","volume":"43","author":"Zhuang","year":"2024","journal-title":"Anaesth Crit Care Pain Med"},{"key":"10.1016\/j.bja.2024.10.016_bib14","doi-asserted-by":"crossref","first-page":"e7480","DOI":"10.1097\/MD.0000000000007480","article-title":"The effect of intraoperative dexmedetomidine on acute kidney injury after pediatric congenital heart surgery: a prospective randomized trial","volume":"96","author":"Jo","year":"2017","journal-title":"Medicine"},{"key":"10.1016\/j.bja.2024.10.016_bib15","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/PCC.0000000000000611","article-title":"Dexmedetomidine is associated with lower incidence of acute kidney injury after congenital heart surgery","volume":"17","author":"Kwiatkowski","year":"2016","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.bja.2024.10.016_bib16","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1111\/pan.13995","article-title":"Effects of intraoperative dexmedetomidine on the incidence of acute kidney injury in pediatric cardiac surgery patients: a randomized controlled trial","volume":"30","author":"Kim","year":"2020","journal-title":"Pediatr Anesth"},{"issue":"1","key":"10.1016\/j.bja.2024.10.016_bib17","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.bja.2024.10.016_bib18","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1001\/jama.2011.1775","article-title":"Nelson textbook of pediatrics","volume":"306","author":"Abbott","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.bja.2024.10.016_bib19","doi-asserted-by":"crossref","first-page":"720","DOI":"10.2214\/AJR.10.6134","article-title":"Intramuscular dexmedetomidine sedation for pediatric MRI and CT","volume":"197","author":"Mason","year":"2011","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.bja.2024.10.016_bib20","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1097\/ALN.0000000000001310","article-title":"Reference values for noninvasive blood pressure in children during anesthesia","volume":"125","author":"de Graaff","year":"2016","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.10.016_bib21","series-title":"Flexible imputation of missing data","first-page":"29","article-title":"Multiple imputation","author":"Rubin","year":"2018"},{"key":"10.1016\/j.bja.2024.10.016_bib22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/pds.3263","article-title":"One-to-many propensity score matching in cohort studies","volume":"21","author":"Rassen","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.bja.2024.10.016_bib23","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00273171.2011.568786","article-title":"An introduction to propensity score methods for reducing the effects of confounding in observational studies","volume":"46","author":"Austin","year":"2011","journal-title":"Multivar Behav Res"},{"key":"10.1016\/j.bja.2024.10.016_bib24","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.bjae.2020.05.004","article-title":"Dexmedetomidine in paediatric anaesthesia","volume":"20","author":"Lin","year":"2020","journal-title":"BJA Educ"},{"key":"10.1016\/j.bja.2024.10.016_bib25","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.bja.2019.12.036","article-title":"Effect of dexmedetomidine on acute kidney injury after aortic surgery: a single-centre, placebo-controlled, randomised controlled trial","volume":"124","author":"Soh","year":"2020","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2024.10.016_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.bjao.2023.100136","article-title":"Incidence of acute kidney injury after noncardiac surgery in patients receiving intraoperative dexmedetomidine: a retrospective study","volume":"6","author":"Paredes-Flores","year":"2023","journal-title":"BJA Open"},{"key":"10.1016\/j.bja.2024.10.016_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2022.110960","article-title":"Association between dexmedetomidine administration and outcomes in critically ill patients with sepsis-associated acute kidney injury","volume":"83","author":"Hu","year":"2022","journal-title":"J\u00a0Clin Anesth"},{"key":"10.1016\/j.bja.2024.10.016_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2023.149402","article-title":"Perioperative acute kidney injury: the renoprotective effect and mechanism of dexmedetomidine","volume":"695","author":"Gao","year":"2024","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.bja.2024.10.016_bib29","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/6136105","article-title":"Organ-protective effects and the underlying mechanism of dexmedetomidine","volume":"2020","author":"Bao","year":"2020","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.bja.2024.10.016_bib30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00011-017-1023-9","article-title":"Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation","volume":"66","author":"Liang","year":"2017","journal-title":"Inflamm Res"},{"key":"10.1016\/j.bja.2024.10.016_bib31","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/292687","article-title":"The effects of dexmedetomidine on secondary acute lung and kidney injuries in the rat model of intra-abdominal sepsis","volume":"2013","author":"Koca","year":"2013","journal-title":"ScientificWorldJournal"},{"key":"10.1016\/j.bja.2024.10.016_bib32","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1007\/s10753-020-01293-y","article-title":"Dexmedetomidine suppressed the biological behavior of HK-2 cells treated with LPS by down-regulating ALKBH5","volume":"43","author":"Zhu","year":"2020","journal-title":"Inflammation"},{"key":"10.1016\/j.bja.2024.10.016_bib33","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1097\/ALN.0b013e3181979440","article-title":"Development and validation of an acute kidney injury risk index for patients undergoing general surgery: results from a national data set","volume":"110","author":"Kheterpal","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2024.10.016_bib34","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000490500","article-title":"Perioperative acute kidney injury: prevention, early recognition, and supportive measures","volume":"140","author":"Romagnoli","year":"2018","journal-title":"Nephron"},{"key":"10.1016\/j.bja.2024.10.016_bib35","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1053\/j.jvca.2017.11.044","article-title":"Use of dexmedetomidine in cardiothoracic and vascular anesthesia","volume":"32","author":"Gallego-Ligorit","year":"2018","journal-title":"J\u00a0Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.bja.2024.10.016_bib36","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/ki.2015.306","article-title":"Perioperative dexmedetomidine reduces the incidence and severity of acute kidney injury following valvular heart surgery","volume":"89","author":"Cho","year":"2016","journal-title":"Kidney Int"},{"key":"10.1016\/j.bja.2024.10.016_bib37","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/s00134-023-07169-7","article-title":"Epidemiology of surgery associated acute kidney injury (EPIS-AKI): a prospective international observational multi-center clinical study","volume":"49","author":"Zarbock","year":"2023","journal-title":"Intensive Care Med"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091224006470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091224006470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:57:27Z","timestamp":1769907447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091224006470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0007091224006470"],"URL":"https:\/\/doi.org\/10.1016\/j.bja.2024.10.016","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intraoperative dexmedetomidine and acute kidney injury in paediatric noncardiac surgery: a retrospective propensity score-matched analysis","name":"articletitle","label":"Article Title"},{"value":"British Journal of Anaesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bja.2024.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 British Journal of Anaesthesia. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}