{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:24:51Z","timestamp":1787955891814,"version":"build-2784847793"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["bjanaesthesia.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Anaesthesia"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bja.2025.09.007","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:49:39Z","timestamp":1760071779000},"page":"1603-1608","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Direct oral anticoagulant management for neuraxial anaesthesia and deep peripheral nerve blocks"],"prefix":"10.1016","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2625-4028","authenticated-orcid":false,"given":"Aiman","family":"Suleiman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4322-9043","authenticated-orcid":false,"given":"William J.","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7893-0596","authenticated-orcid":false,"given":"Matthias","family":"Eikermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Tam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Douketis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3175-461X","authenticated-orcid":false,"given":"Alex C.","family":"Spyropoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bja.2025.09.007_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.007338","article-title":"Evidence gaps in the era of non-vitamin K oral anticoagulants","volume":"7","author":"Aronis","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.bja.2025.09.007_bib2","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1161\/CIRCULATIONAHA.113.005754","volume":"129","author":"Sherwood","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.bja.2025.09.007_bib3","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12959-017-0137-1","article-title":"Perioperative management of patients on direct oral anticoagulants","volume":"15","author":"Dubois","year":"2017","journal-title":"Thromb J"},{"key":"10.1016\/j.bja.2025.09.007_bib4","article-title":"Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine evidence-based guidelines (fifth edition)","author":"Kopp","year":"2025","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.bja.2025.09.007_bib5","doi-asserted-by":"crossref","first-page":"ii57","DOI":"10.1093\/bja\/aev381","article-title":"Epidemiology, trends, and disparities in regional anaesthesia for orthopaedic surgery","volume":"115","author":"Cozowicz","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2025.09.007_bib6","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.bjae.2017.10.002","article-title":"Regional anaesthesia and outcomes","volume":"18","author":"Hutton","year":"2018","journal-title":"BJA Educ"},{"key":"10.1016\/j.bja.2025.09.007_bib7","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.bja.2024.04.044","article-title":"Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence","volume":"133","author":"Hewson","year":"2024","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2025.09.007_bib8","doi-asserted-by":"crossref","first-page":"e207","DOI":"10.1016\/j.chest.2022.07.025","article-title":"Perioperative management of antithrombotic therapy: an American College of Chest Physicians Clinical Practice Guideline","volume":"162","author":"Douketis","year":"2022","journal-title":"Chest"},{"key":"10.1016\/j.bja.2025.09.007_bib9","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/EJA.0000000000001600","article-title":"Regional anaesthesia in patients on antithrombotic drugs: joint ESAIC\/ESRA guidelines","volume":"39","author":"Kietaibl","year":"2022","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.bja.2025.09.007_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/bja\/aen360","article-title":"Major complications of central neuraxial block: report on the Third National Audit Project of the Royal College of Anaesthetists","volume":"102","author":"Cook","year":"2009","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2025.09.007_bib11","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1097\/00000542-200410000-00021","article-title":"Severe neurological complications after central neuraxial blockades in Sweden 1990\u20131999","volume":"101","author":"Moen","year":"2004","journal-title":"Anesthesiology"},{"key":"10.1016\/j.bja.2025.09.007_bib12","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/bja\/aen300","article-title":"Effectiveness and safety of postoperative pain management: a survey of 18 925 consecutive patients between 1998 and 2006 (2nd revision): a database analysis of prospectively raised data","volume":"101","author":"P\u00f6pping","year":"2008","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bja.2025.09.007_bib13","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1111\/jth.13344","article-title":"To measure or not to measure direct oral anticoagulants before surgery or invasive procedures","volume":"14","author":"Tripodi","year":"2016","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.bja.2025.09.007_bib14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/AAP.0000000000000763","article-title":"Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine evidence-based guidelines (Fourth Edition)","volume":"43","author":"Horlocker","year":"2018","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.bja.2025.09.007_bib15","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/anae.12359","volume":"68","year":"2013","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bja.2025.09.007_bib16","doi-asserted-by":"crossref","first-page":"e351","DOI":"10.1161\/CIR.0000000000001285","article-title":"AHA\/ACC\/ACS\/ASNC\/HRS\/SCA\/SCCT\/SCMR\/SVM guideline for perioperative cardiovascular management for noncardiac surgery: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"150","author":"Thompson","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.bja.2025.09.007_bib17","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1111\/jth.15415","article-title":"Risks associated with discontinuation of oral anticoagulation in newly diagnosed patients with atrial fibrillation: results from the GARFIELD-AF Registry","volume":"19","author":"Cools","year":"2021","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.bja.2025.09.007_bib18","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1182\/blood-2012-06-415943","article-title":"How I treat anticoagulated patients undergoing an elective procedure or surgery","volume":"120","author":"Spyropoulos","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.bja.2025.09.007_bib19","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/AAP.0000000000000223","volume":"40","author":"Narouze","year":"2015","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.bja.2025.09.007_bib20","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1161\/CIRCULATIONAHA.111.090464","article-title":"Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial","volume":"126","author":"Healey","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.bja.2025.09.007_bib21","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1001\/jamainternmed.2019.2431","article-title":"Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant","volume":"179","author":"Douketis","year":"2019","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.bja.2025.09.007_bib22","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1111\/jth.14598","volume":"17","author":"Spyropoulos","year":"2019","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.bja.2025.09.007_bib23","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1111\/j.1538-7836.2007.02729.x","article-title":"Bridging therapy in patients on long-term oral anticoagulants who require surgery: the Prospective Peri-operative Enoxaparin Cohort Trial (PROSPECT)","volume":"5","author":"Dunn","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.bja.2025.09.007_bib24","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1016\/j.jtha.2025.03.003","article-title":"Perioperative management of direct oral anticoagulants in patients having a high-bleed-risk surgery or neuraxial procedure: the Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE)-2 pilot randomized trial","volume":"23","author":"Douketis","year":"2025","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.bja.2025.09.007_bib25","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.15227","article-title":"Regional anesthesia for transplantation surgery \u2013 a white paper part 2: abdominal transplantation surgery","volume":"38","author":"Ander","year":"2024","journal-title":"Clin Transplant"}],"container-title":["British Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091225006312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0007091225006312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T04:27:05Z","timestamp":1779769625000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0007091225006312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0007091225006312"],"URL":"https:\/\/doi.org\/10.1016\/j.bja.2025.09.007","relation":{},"ISSN":["0007-0912"],"issn-type":[{"value":"0007-0912","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct oral anticoagulant management for neuraxial anaesthesia and deep peripheral nerve blocks","name":"articletitle","label":"Article Title"},{"value":"British Journal of Anaesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bja.2025.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}