{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:04:08Z","timestamp":1761419048867,"version":"3.37.3"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,28]],"date-time":"2016-05-28T00:00:00Z","timestamp":1464393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Brazilian Journal of Infectious Diseases"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.bjid.2016.04.007","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T11:28:24Z","timestamp":1465212504000},"page":"354-359","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diagnostic-driven antifungal therapy in neutropenic patients using the D-index and serial serum galactomannan testing"],"prefix":"10.1016","volume":"20","author":[{"given":"Marcia","family":"Garnica","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Sinhorelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Madeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Portugal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcio","family":"Nucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjid.2016.04.007_bib0135","first-page":"1068","article-title":"The epidemiology of fungal infections in patients with hematologic malignancies: the SEIFEM-2004 study","volume":"91","author":"Pagano","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.bjid.2016.04.007_bib0140","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/1469-0691.12002","article-title":"Invasive fungal diseases in haematopoietic cell transplant recipients and in patients with acute myeloid leukaemia or myelodysplasia in Brazil","volume":"19","author":"Nucci","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.bjid.2016.04.007_bib0145","doi-asserted-by":"crossref","first-page":"3230","DOI":"10.1002\/cncr.10610","article-title":"Antifungal prophylaxis for severely neutropenic chemotherapy recipients: a meta analysis of randomized-controlled clinical trials","volume":"94","author":"Bow","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.bjid.2016.04.007_bib0150","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s11908-006-0029-1","article-title":"Empiric antifungal therapy in neutropenic cancer patients","volume":"8","author":"Rotstein","year":"2006","journal-title":"Curr Infect Dis Rep"},{"key":"10.1016\/j.bjid.2016.04.007_bib0155","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1473-3099(13)70076-8","article-title":"Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial","volume":"13","author":"Morrissey","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0160","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1086\/496927","article-title":"Galactomannan and computed tomography-based preemptive antifungal therapy in neutropenic patients at high risk for invasive fungal infection: a prospective feasibility study","volume":"41","author":"Maertens","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0165","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1086\/597395","article-title":"Empirical versus preemptive antifungal therapy for high-risk, febrile, neutropenic patients: a randomized, controlled trial","volume":"48","author":"Cordonnier","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0170","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1086\/505870","article-title":"Comparison of epidemiological, clinical, and biological features of invasive aspergillosis in neutropenic and nonneutropenic patients: a 6-year survey","volume":"43","author":"Cornillet","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0175","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/cncr.11510","article-title":"Outcome predictors of 84 patients with hematologic malignancies and Fusarium infection","volume":"98","author":"Nucci","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.bjid.2016.04.007_bib0180","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1182\/blood-2002-05-1496","article-title":"Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors","volume":"100","author":"Marr","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.bjid.2016.04.007_bib0185","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1200\/JCO.2008.21.0856","article-title":"Index to predict invasive mould infection in high-risk neutropenic patients based on the area over the neutrophil curve","volume":"27","author":"Portugal","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bjid.2016.04.007_bib0190","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1086\/503427","article-title":"Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis","volume":"42","author":"Pfeiffer","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0195","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1086\/421944","article-title":"Beta-d-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome","volume":"39","author":"Odabasi","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0200","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1086\/588660","volume":"46","author":"De","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0205","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1086\/657065","article-title":"Probable invasive aspergillosis without prespecified radiologic findings: proposal for inclusion of a new category of aspergillosis and implications for studying novel therapies","volume":"51","author":"Nucci","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0210","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3324\/haematol.2012.061952","article-title":"The role of antifungal treatment in hematology","volume":"97","author":"Maertens","year":"2012","journal-title":"Haematologica"},{"key":"10.1016\/j.bjid.2016.04.007_bib0215","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/0002-9343(89)90441-5","article-title":"Empiric antifungal therapy in febrile granulocytopenic patients. EORTC International Antimicrobial Therapy Cooperative Group","volume":"86","year":"1989","journal-title":"Am J Med"},{"key":"10.1016\/j.bjid.2016.04.007_bib0220","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0002-9343(82)90594-0","article-title":"Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia","volume":"72","author":"Pizzo","year":"1982","journal-title":"Am J Med"},{"key":"10.1016\/j.bjid.2016.04.007_bib0225","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/cid\/ciq147","article-title":"Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America","volume":"52","author":"Freifeld","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0230","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/bmt.2010.175","article-title":"European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3 \u2013 2009 update","volume":"46","author":"Maertens","year":"2011","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.bjid.2016.04.007_bib0235","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.3324\/haematol.2011.042598","article-title":"The use and efficacy of empirical versus pre-emptive therapy in the management of fungal infections: the HEMA e-Chart Project","volume":"96","author":"Pagano","year":"2011","journal-title":"Haematologica"},{"key":"10.1016\/j.bjid.2016.04.007_bib0240","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1200\/JCO.2009.21.8032","article-title":"Clinically driven diagnostic antifungal approach in neutropenic patients: a prospective feasibility study","volume":"28","author":"Girmenia","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.bjid.2016.04.007_bib0245","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1056\/NEJMoa040446","article-title":"Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia","volume":"351","author":"Walsh","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bjid.2016.04.007_bib0250","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1086\/429921","article-title":"Antifungal therapy decreases sensitivity of the Aspergillus galactomannan enzyme immunoassay","volume":"40","author":"Marr","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0255","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1086\/651161","article-title":"Galactomannan detection and diagnosis of invasive aspergillosis","volume":"50","author":"Donnelly","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2016.04.007_bib0260","doi-asserted-by":"crossref","first-page":"e65776","DOI":"10.1371\/journal.pone.0065776","article-title":"Performance of serum biomarkers for the early detection of invasive aspergillosis in febrile, neutropenic patients: a multi-state model","volume":"8","author":"Schwarzinger","year":"2013","journal-title":"PLOS ONE"}],"container-title":["The Brazilian Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1413867016300800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1413867016300800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T11:49:18Z","timestamp":1498304958000},"score":1,"resource":{"primary":{"URL":"http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1413867016300800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S1413867016300800"],"URL":"https:\/\/doi.org\/10.1016\/j.bjid.2016.04.007","relation":{},"ISSN":["1413-8670"],"issn-type":[{"type":"print","value":"1413-8670"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic-driven antifungal therapy in neutropenic patients using the D-index and serial serum galactomannan testing","name":"articletitle","label":"Article Title"},{"value":"The Brazilian Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.bjid.2016.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Editora Ltda.","name":"copyright","label":"Copyright"}]}}