{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T23:30:51Z","timestamp":1774308651681,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T00:00:00Z","timestamp":1689552000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Brazilian Journal of Infectious Diseases"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.bjid.2023.102791","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T20:42:52Z","timestamp":1690231372000},"page":"102791","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cohort study of hospitalized patients with COVID-19 at Brazilian tertiary-care hospital: Occurrence of adverse events and mortality"],"prefix":"10.1016","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8617-9050","authenticated-orcid":false,"given":"Mait\u00ea Vasconcelos","family":"Luz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1481-9303","authenticated-orcid":false,"given":"Julian Furtado","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8209-4252","authenticated-orcid":false,"given":"Hugo Dugolin","family":"Ceccato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0816-9655","authenticated-orcid":false,"given":"Paulo Jos\u00e9","family":"de Souza J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8778-7605","authenticated-orcid":false,"given":"Pedro Maximink","family":"Villar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1810-824X","authenticated-orcid":false,"given":"Paulo Roberto Ara\u00fajo","family":"Mendes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6976-8884","authenticated-orcid":false,"given":"Mari\u00e2ngela Ribeiro","family":"Resende","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7669-4841","authenticated-orcid":false,"given":"M\u00f4nica Corso","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7814-5387","authenticated-orcid":false,"given":"Lucieni","family":"Oliveira Conterno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjid.2023.102791_bib0001","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1056\/NEJMcp2009575","article-title":"Severe COVID-19","volume":"383","author":"Berlin","year":"2020","journal-title":"New Engl J Med"},{"key":"10.1016\/j.bjid.2023.102791_bib0002","first-page":"271","article-title":"Clinical characterization of 162 COVID-19 patients in Israel: preliminary report from a Large Tertiary Center","author":"Itelman","year":"2020","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.bjid.2023.102791_bib0003","article-title":"Impacto das infec\u00e7\u00f5es hospitalares na mortalidade de pacientes com COVID-19 internados na uti de um grande hospital","volume":"26","author":"Souza","year":"2022","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0004","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1017\/ice.2020.126","article-title":"Nosocomial infection among patients with COVID-19: a retrospective data analysis of 918 cases from a single center in Wuhan, China","volume":"41","author":"He","year":"2020","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.bjid.2023.102791_bib0005","unstructured":"World Health Organization (WHO). Preventing the COVID-19 pandemic from causing an antibiotic resistance catastrophe. [Internet]. [place unknown]: WHO Regional Office for Europe; [updated 2020 Nov 18; cited 2021 Jun 22]. Available from: https:\/\/www.who.int\/europe\/news\/item\/18-11-2020-preventing-the-covid-19-pandemic-from-causing-an-antibiotic-resistance-catastrophe#:\u223c:text=Preventing%20the%20COVID%2D19%20pandemic%20from%20causing%20an%20antibiotic%20resistance%20catastrophe,-18%20November%202020&text=According%20to%20research%20conducted%20by,accelerated%20spread%20of%20antimicrobial%20resistance."},{"key":"10.1016\/j.bjid.2023.102791_bib0006","doi-asserted-by":"crossref","unstructured":"Wei W., Ortwine J.K., Mang N.S., Joseph C., Hall B.C., Prokesch B.C. Limited role for antibiotics in COVID-19: scarce evidence of bacterial coinfection. medRxiv. 2020;2020-06.","DOI":"10.1101\/2020.06.16.20133181"},{"key":"10.1016\/j.bjid.2023.102791_bib0007","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1377\/hlthaff.2020.00455","article-title":"Estimating the infection fatality rate among symptomatic covid-19 cases in the United States: study estimates the COVID-19 infection fatality rate at the US county level","volume":"39","author":"Basu","year":"2020","journal-title":"Health Aff"},{"key":"10.1016\/j.bjid.2023.102791_bib0008","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course, and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.bjid.2023.102791_bib0009","series-title":"Protocolo De Manejo Cl\u00ednico Para o Novo Coronav\u00edrus (2019-nCoV) [Internet]","year":"2020"},{"key":"10.1016\/j.bjid.2023.102791_bib0010","series-title":"Gest\u00e3o De Riscos e Investiga\u00e7\u00e3o De Eventos Adversos Relacionados \u00e0 Assist\u00eancia \u00e0 Sa\u00fade [Internet]","year":"2017"},{"key":"10.1016\/j.bjid.2023.102791_bib0011","series-title":"NOTA T\u00c9CNICA GVIMS\/GGTES n\u00b0 03\/2023 \u2012 Crit\u00e9rios diagn\u00f3sticos Das Infec\u00e7\u00f5es Relacionadas \u00e0 Assist\u00eancia \u00e0 Sa\u00fade (IRAS): Notifica\u00e7\u00e3o Nacional Obrigat\u00f3ria Para o Ano De 2023 [Internet]","year":"2023"},{"key":"10.1016\/j.bjid.2023.102791_bib0012","unstructured":"BRASIL. Minist\u00e9rio da Sa\u00fade. Doen\u00e7a pelo Coronav\u00edrus 2019. COVID-19: Boletim Epidemiol\u00f3gico, Bras\u00edlia, n. 145, janeiro. 2022. Dispon\u00edvel em: https:\/\/www.gov.br\/saude\/pt-br\/centrais-de-conteudo\/publicacoes\/boletins\/epidemiologicos\/covid-19\/2022\/boletim-epidemiologico-no-145-boletim-coe-coronavirus\/view."},{"key":"10.1016\/j.bjid.2023.102791_bib0013","series-title":"Clinical Management of COVID-19: Interim Guidance, 27 May 2020","year":"2020"},{"key":"10.1016\/j.bjid.2023.102791_bib0014","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/s41591-020-0968-3","article-title":"Extrapulmonary manifestations of COVID-19","volume":"26","author":"Gupta","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.bjid.2023.102791_bib0015","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1007\/s00345-020-03246-4","article-title":"A systematic review on COVID-19: urological manifestations, viral RNA detection and special considerations in urological conditions","volume":"39","author":"Chan","year":"2021","journal-title":"World J Urol"},{"key":"10.1016\/j.bjid.2023.102791_bib0016","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.chest.2021.04.002","article-title":"Hospital-acquired infections in critically ill patients with COVID-19","volume":"160","author":"Grasselli","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.bjid.2023.102791_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.bjid.2020.101081","article-title":"Procalcitonina como biomarcador de pneumonia associada \u00e0 ventila\u00e7\u00e3o mec\u00e2nica em pacientes com COVID-19: \u00e9 uma ferramenta \u00fatil no controle de antibi\u00f3tico?","volume":"25","author":"C\u00f4rtes","year":"2021","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.bjid.2021.102227","article-title":"An\u00e1lise comparativa da resist\u00eancia bacteriana de microrganismos causadores de bacteremia em pacientes cr\u00edticos nos per\u00edodos pr\u00e9-pandemia e COVID-19 em um hospital terci\u00e1rio privado do Rio de Janeiro","volume":"26","author":"Dias","year":"2022","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0019","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1093\/cid\/ciaa524","article-title":"Coronavirus disease 2019, superinfections, and antimicrobial development: what can we expect?","volume":"71","author":"Clancy","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0020","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1093\/cid\/ciaa530","article-title":"Bacterial and fungal coinfection in individuals with coronavirus: a rapid review to support COVID-19 antimicrobial prescribing","volume":"71","author":"Rawson","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0245772","article-title":"In-hospital mortality from severe COVID-19 in a tertiary care center in Mexico City; causes of death, risk factors and the impact of hospital saturation","volume":"16","author":"Olivas-Martinez","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.bjid.2023.102791_bib0022","article-title":"In-hospital mortality and severe outcomes after hospital discharge due to COVID-19: a prospective multicenter study from Brazil","volume":"11","author":"Perazzo","year":"2022","journal-title":"Lancet Reg Health Am"},{"key":"10.1016\/j.bjid.2023.102791_bib0023","unstructured":"Prefeitura Municipal de Campinas (BR) [City Hall of Campinas (Brazil)]. Boletim epidemiol\u00f3gico Semanal \u2013 Novo Coronavirus COVID-19 [Internet]. Campinas (SP); 2021 Feb 3 [updated 2021 Feb 4; cited 2023 May 28]. Available from: https:\/\/covid-19.campinas.sp.gov.br\/sites\/covid-19.campinas.sp.gov.br\/files\/recomendacoes-tecnicas\/Boletim%20Epidemiol%C3%B3gico_%20INFORME_SEMANAL%20COVID-19%20Campinas_%2003-02-%202021.pdf."},{"key":"10.1016\/j.bjid.2023.102791_bib0024","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1111\/j.1523-1755.2005.67130.x","article-title":"Acute renal impairment in coronavirus-associated severe acute respiratory syndrome","volume":"67","author":"Chu","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.bjid.2023.102791_bib0025","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijid.2022.02.041","article-title":"The impact of COVID-19 on health care\u2013associated infections in intensive care units in low-and middle-income countries: International Nosocomial Infection Control Consortium (INICC) findings","volume":"118","author":"Rosenthal","year":"2022","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.bjid.2023.102791_bib0026","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3390\/antibiotics10050545","article-title":"Ventilator-associated pneumonia in patients with COVID-19: a systematic review and meta-analysis","volume":"10","author":"Ippolito","year":"2021","journal-title":"Antibiotics"}],"container-title":["The Brazilian Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S141386702300051X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S141386702300051X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:00:07Z","timestamp":1761408007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S141386702300051X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S141386702300051X"],"URL":"https:\/\/doi.org\/10.1016\/j.bjid.2023.102791","relation":{},"ISSN":["1413-8670"],"issn-type":[{"value":"1413-8670","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cohort study of hospitalized patients with COVID-19 at Brazilian tertiary-care hospital: Occurrence of adverse events and mortality","name":"articletitle","label":"Article Title"},{"value":"The Brazilian Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjid.2023.102791","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Sociedade Brasileira de Infectologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"102791"}}