{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:24:32Z","timestamp":1771467872690,"version":"3.50.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T00:00:00Z","timestamp":1468540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"CNPq, CAPES"},{"DOI":"10.13039\/501100004263","name":"FAPERGS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brazilian Journal of Microbiology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.bjm.2016.07.017","type":"journal-article","created":{"date-parts":[[2016,7,30]],"date-time":"2016-07-30T04:21:54Z","timestamp":1469852514000},"page":"896-901","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Cytotoxicity and anti-Sporothrix brasiliensis activity of the Origanum majorana Linn. oil"],"prefix":"10.1007","volume":"47","author":[{"given":"Stefanie Bressan","family":"Waller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel Martins","family":"Madrid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanny","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Picoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlete Brum","family":"Cleff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Os\u00f3rio","family":"de Faria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio Carlos Ara\u00fajo","family":"Meireles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Roberto Braga","family":"de Mello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"10.1016\/j.bjm.2016.07.017_bib0005","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/JCM.00808-07","article-title":"Sporothrix brasiliensis, S. globosa and S. mexicana, three new Sporothrix species of clinical interest","volume":"45","author":"Marimon","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0010","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1128\/AAC.01012-07","article-title":"In vitro antifungal susceptibilities of five species of Sporothrix schenckii","volume":"52","author":"Marimon","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"issue":"10","key":"10.1016\/j.bjm.2016.07.017_bib0015","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1590\/S0102-311X2012001000006","article-title":"Urban sporotrichosis: a neglected epidemic in Rio de Janeiro, Brazil","volume":"28","author":"Silva","year":"2012","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"10.1016\/j.bjm.2016.07.017_bib0020","first-page":"5","article-title":"New observations on the ecology and epidemiology of Sporothrix schenckii and sporotrichosis","volume":"60","author":"Carrada-Bravo","year":"2013","journal-title":"Rev Latinoam Patol Clin"},{"issue":"6","key":"10.1016\/j.bjm.2016.07.017_bib0025","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1590\/S0103-84782004000600047","article-title":"Esporotricose felina com envolvimento humano na cidade de Pelotas, RS, Brasil","volume":"34","author":"Xavier","year":"2004","journal-title":"Ci\u00eanc Rural"},{"key":"10.1016\/j.bjm.2016.07.017_bib0030","first-page":"8","article-title":"Complexo Sporothrix schenckii. Revis\u00e3o de parte de literatura e considera\u00e7\u00f5es sobre diagn\u00f3stico e a epidemiologia","volume":"20","author":"Cruz","year":"2011","journal-title":"Vet Zootec"},{"key":"10.1016\/j.bjm.2016.07.017_bib0035","doi-asserted-by":"crossref","first-page":"e2281","DOI":"10.1371\/journal.pntd.0002281","article-title":"Phylogenetic analysis reveals a high prevalence of Sporothrix brasiliensis in feline sporotrichosis outbreaks","volume":"7","author":"Rodrigues","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.bjm.2016.07.017_bib0040","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s12917-014-0269-5","article-title":"Feline sporotrichosis due to Sporothrix brasiliensis: an emerging animal infection in S\u00e3o Paulo, Brazil","volume":"10","author":"Montenegro","year":"2014","journal-title":"BMC Vet Res"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0045","doi-asserted-by":"crossref","first-page":"250","DOI":"10.11606\/S1413-95962011000300010","article-title":"Esporotricose","volume":"48","author":"Larsson","year":"2011","journal-title":"Braz J Vet Res Anim Sci"},{"issue":"7","key":"10.1016\/j.bjm.2016.07.017_bib0050","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1136\/vr.b4768","article-title":"Use of local hyperthermia to treat sporotrichosis in a cat","volume":"166","author":"Honse","year":"2010","journal-title":"Vet Rec"},{"issue":"2","key":"10.1016\/j.bjm.2016.07.017_bib0055","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1863-2378.2008.01227.x","article-title":"Feline sporotrichosis in the southern region of Rio Grande do Sul, Brazil: clinical, zoonotic and therapeutic aspects","volume":"57","author":"Madrid","year":"2010","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.bjm.2016.07.017_bib0060","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1136\/vr.166.10.290","article-title":"Response to azolic antifungal agents for treating feline sporotrichosis","volume":"166","author":"Pereira","year":"2010","journal-title":"Vet Rec"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0065","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1439-0507.2009.01701.x","article-title":"Antifungal susceptibility profile in vitro of Sporothrix schenckii in two growth phases and by two methods: microdilution and E-test","volume":"53","author":"Gutierrez-Galhardo","year":"2010","journal-title":"Mycoses"},{"key":"10.1016\/j.bjm.2016.07.017_bib0070","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/1471-2334-14-219","article-title":"Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis","volume":"14","author":"Rodrigues","year":"2014","journal-title":"BMC Infect Dis"},{"issue":"5","key":"10.1016\/j.bjm.2016.07.017_bib0075","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.nbt.2009.03.007","article-title":"Recent advancements for the evaluation of anti-viral activities of natural products","volume":"25","author":"Chattopadhyay","year":"2009","journal-title":"N Biotechnol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0080","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1055\/s-2008-1074884","article-title":"Antispasmodic activity of Origanum compactum","volume":"38","author":"Van Den Broucke","year":"1980","journal-title":"Planta Med"},{"key":"10.1016\/j.bjm.2016.07.017_bib0085","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0308-8146(01)00233-3","article-title":"Antioxidant effects of Origanum majorana L. on superoxide anion radicals","volume":"75","author":"Jun","year":"2001","journal-title":"Food Chem"},{"key":"10.1016\/j.bjm.2016.07.017_bib0090","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.foodres.2004.07.006","article-title":"Essential oil composition and antimicrobial activity of Origanum majorana L. extracts obtained with ethyl alcohol and supercritical carbon dioxide","volume":"38","author":"V\u00e1gi","year":"2005","journal-title":"Food Res Int"},{"key":"10.1016\/j.bjm.2016.07.017_bib0095","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1021\/jf990835x","article-title":"GC\u2013MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum","volume":"48","author":"Daferera","year":"2000","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.bjm.2016.07.017_bib0100","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0378-1097(03)00890-5","article-title":"Susceptibility of methicillin-resistant Staphylococci to oregano essential oil, carvacrol and thymol","volume":"230","author":"Nostro","year":"2004","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.bjm.2016.07.017_bib0105","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.fm.2007.07.003","article-title":"Application of Origanum majorana L. essential oil as an antimicrobial agent in sausage","volume":"25","author":"Busatta","year":"2008","journal-title":"Food Microbiol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0110","first-page":"239","article-title":"Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components","volume":"36","author":"Erdo\u011fan","year":"2012","journal-title":"Turk J Biol"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0115","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1590\/S1984-82502010000300013","article-title":"Efficacy of Origanum essential oils for inhibition of potentially pathogenic fungi","volume":"46","author":"Souza","year":"2010","journal-title":"Braz J Pharm Sci"},{"key":"10.1016\/j.bjm.2016.07.017_bib0120","series-title":"Potencial antif\u00fangico e toxicidade de \u00f3leos essenciais da fam\u00edlia Lamiaceae","author":"Santin","year":"2013"},{"issue":"1\u20132","key":"10.1016\/j.bjm.2016.07.017_bib0125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.bjm.2016.07.017_bib0130","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.diagmicrobio.2014.01.004","article-title":"Genotyping species of the Sporothrix schenckii complex by PCR-RFLP of calmodulin","volume":"78","author":"Rodrigues","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.bjm.2016.07.017_bib0135","series-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts. M27-A3 Guideline. Approved Standard","author":"CLSI \u2013 Clinical and Laboratory Standards Institute","year":"2008"},{"key":"10.1016\/j.bjm.2016.07.017_bib0140","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1086\/522765","article-title":"Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America","volume":"45","author":"Kauffman","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.bjm.2016.07.017_bib0145","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1590\/S0036-46652011000200006","article-title":"Cutaneous sporotrichosis treatment with potassium iodide. A 24 year experience in S\u00e3o Paulo State, Brazil","volume":"53","author":"Yamada","year":"2007","journal-title":"Rev Inst Med Trop S\u00e3o Paulo"},{"key":"10.1016\/j.bjm.2016.07.017_bib0150","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.2460\/javma.2004.224.1623","article-title":"Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998\u20132001)","volume":"224","author":"Schubach","year":"2004","journal-title":"J Am Vet Med Assoc"},{"issue":"4","key":"10.1016\/j.bjm.2016.07.017_bib0155","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s11046-011-9509-4","article-title":"Epidemiological findings and laboratory evaluation of sporotrichosis: a description of 103 cases in cats and dogs in southern Brazil","volume":"173","author":"Madrid","year":"2012","journal-title":"Mycopathologia"},{"key":"10.1016\/j.bjm.2016.07.017_bib0160","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/jvim.12219","article-title":"Bioequivalence of orally administered generic, compounded, and innovator-formulated itraconazole in healthy dogs","volume":"28","author":"Mawby","year":"2014","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.bjm.2016.07.017_bib0165","series-title":"Comparative and Veterinary Pharmacology","author":"Cunningham","year":"2010"},{"key":"10.1016\/j.bjm.2016.07.017_bib0170","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1863-2378.2012.01506.x","article-title":"Treatment abandonment in feline sporotrichosis \u2013 study of 147 cases","volume":"60","author":"Chaves","year":"2013","journal-title":"Zoonoses Public Health"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0175","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.mycmed.2011.07.002","article-title":"Antifungal activity of Pterocaulon species (Asteraceae) against Sporothrix schenckii","volume":"21","author":"Stopiglia","year":"2011","journal-title":"J Mycol Med"},{"issue":"4","key":"10.1016\/j.bjm.2016.07.017_bib0180","first-page":"342","article-title":"In vitro susceptibility of the Sporothrix brasiliensis to aqueous extracts of green-tea (Camellia sinensis L. Kuntze)","volume":"9","author":"Waller","year":"2015","journal-title":"Acta Vet Bras"},{"issue":"5","key":"10.1016\/j.bjm.2016.07.017_bib0185","first-page":"54","article-title":"Potential of Rosemary oil to be used in drug-resistant infections","volume":"13","author":"Luqman","year":"2007","journal-title":"Altern Ther Health Med"},{"issue":"2","key":"10.1016\/j.bjm.2016.07.017_bib0190","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1590\/S0102-09352008000200039","article-title":"In vitro activity of the essential oil of Origanum vulgare against Sporothrix schenckii","volume":"60","author":"Cleff","year":"2008","journal-title":"Arq Bras Med Vet Zootec"},{"key":"10.1016\/j.bjm.2016.07.017_bib0195","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/573518","article-title":"Exploring the anti-Burkholderia cepacia complex activity of essential oils: a preliminary analysis","author":"Maida","year":"2014","journal-title":"Evid Based Complement Altern Med"},{"key":"10.1016\/j.bjm.2016.07.017_bib0200","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/269161","article-title":"In vitro antibacterial activity of essential oils against Streptococcus pyogenes","author":"Sfeir","year":"2013","journal-title":"Evid Based Complement Altern Med"},{"key":"10.1016\/j.bjm.2016.07.017_bib0205","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0168-1605(01)00447-0","article-title":"Impedance measurements to study the antimicrobial activity of essential oils from Lamiaceae and Compositae","volume":"67","author":"Marino","year":"2001","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0210","first-page":"23","article-title":"Origanum marjoran L. in medicine and foods","volume":"2","author":"Ferrara","year":"2003","journal-title":"Ingred Aliment"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0215","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.ijfoodmicro.2013.08.014","article-title":"Antimicrobial activity of essential oils and five terpenoid compounds against Campylobacter jejuni in pure and mixed culture experiments","volume":"166","author":"Kurekci","year":"2013","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0220","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0168-1605(00)00480-3","article-title":"Influence of carvacrol on growth and toxin production by Bacillus cereus","volume":"64","author":"Ultee","year":"2001","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.bjm.2016.07.017_bib0225","series-title":"Manual de Toxicologia Veterin\u00e1ria","author":"Nogueira","year":"2011"},{"issue":"3","key":"10.1016\/j.bjm.2016.07.017_bib0230","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1590\/S0100-40422005000300026","article-title":"Plantas Medicinais: Cura Segura?","volume":"28","author":"Veiga","year":"2005","journal-title":"Qu\u00edm Nova"},{"key":"10.1016\/j.bjm.2016.07.017_bib0235","series-title":"Oregano: The Genera Origanum and Lippia, Medicinal and Aromatic Plants \u2013 Industrial Profiles","first-page":"177","article-title":"The biological\/pharmacological activity of the oregano genus","author":"Bari\u010devi\u010d","year":"2002"},{"key":"10.1016\/j.bjm.2016.07.017_bib0240","series-title":"Plantas Medicinais no Brasil: Nativas e Ex\u00f3ticas Cultivadas","author":"Lorenzi","year":"2006"}],"container-title":["Brazilian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1517838216306086?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1517838216306086?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T23:45:35Z","timestamp":1568245535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1517838216306086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S1517838216306086"],"URL":"https:\/\/doi.org\/10.1016\/j.bjm.2016.07.017","relation":{},"ISSN":["1517-8382"],"issn-type":[{"value":"1517-8382","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytotoxicity and anti-Sporothrix brasiliensis activity of the Origanum majorana Linn. oil","name":"articletitle","label":"Article Title"},{"value":"Brazilian Journal of Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjm.2016.07.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.","name":"copyright","label":"Copyright"}]}}