{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T10:46:37Z","timestamp":1763894797839},"reference-count":16,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.bjoms.2007.04.015","type":"journal-article","created":{"date-parts":[[2007,6,8]],"date-time":"2007-06-08T12:54:26Z","timestamp":1181307266000},"page":"617-622","source":"Crossref","is-referenced-by-count":44,"title":["Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma"],"prefix":"10.1016","volume":"45","author":[{"given":"Richard J.","family":"Shaw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian L.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia A.","family":"Woolgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon N.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Field","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Triantafillos","family":"Liloglou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet M.","family":"Risk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjoms.2007.04.015_bib1","unstructured":"Office of National Statistics, Welsh Cancer Intelligence Surveillance Unit, 2000; 2004."},{"key":"10.1016\/j.bjoms.2007.04.015_bib2","unstructured":"Shah JP BJJJ. Oral Cancer. Martin Dunitz, Taylor & Francis; 1999."},{"issue":"2","key":"10.1016\/j.bjoms.2007.04.015_bib3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S1368-8375(02)00030-1","article-title":"Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread","volume":"39","author":"Woolgar","year":"2003","journal-title":"Oral Oncol"},{"issue":"10","key":"10.1016\/j.bjoms.2007.04.015_bib4","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/hed.20036","article-title":"The influence of the pattern of mandibular invasion on recurrence and survival in oral squamous cell carcinoma","volume":"26","author":"Shaw","year":"2004","journal-title":"Head Neck"},{"issue":"10","key":"10.1016\/j.bjoms.2007.04.015_bib5","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1288\/00005537-198610000-00015","article-title":"Prognostic implications of perineural spread in squamous carcinomas of the head and neck","volume":"96","author":"Soo","year":"1986","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.bjoms.2007.04.015_bib6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.oraloncology.2006.01.012","article-title":"A questionnaire survey of current UK practice for adjuvant radiotherapy following surgery for oral and oropharyngeal squamous cell carcinoma","volume":"43","author":"Blackburn","year":"2007","journal-title":"Oral Oncol"},{"issue":"5588","key":"10.1016\/j.bjoms.2007.04.015_bib7","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1126\/science.297.5588.1807d","article-title":"Cancer epigenetics and methylation","volume":"297","author":"Esteller","year":"2002","journal-title":"Science"},{"issue":"42","key":"10.1016\/j.bjoms.2007.04.015_bib8","doi-asserted-by":"crossref","first-page":"6479","DOI":"10.1038\/sj.onc.1206774","article-title":"Cancer epigenetics","volume":"22","author":"Momparler","year":"2003","journal-title":"Oncogene"},{"issue":"2","key":"10.1016\/j.bjoms.2007.04.015_bib9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ijom.2005.06.014","article-title":"The epigenetics of oral cancer","volume":"35","author":"Shaw","year":"2006","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.bjoms.2007.04.015_bib10","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.bbrc.2005.10.095","article-title":"Methylation-based molecular margin analysis in hepatocellular carcinoma","volume":"338","author":"Yang","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"issue":"15","key":"10.1016\/j.bjoms.2007.04.015_bib11","doi-asserted-by":"crossref","first-page":"5131","DOI":"10.1158\/1078-0432.CCR-03-0763","article-title":"Promoter hypermethylation of resected bronchial margins: a field defect of changes?","volume":"10","author":"Guo","year":"2004","journal-title":"Clin Cancer Res"},{"issue":"1","key":"10.1016\/j.bjoms.2007.04.015_bib12","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1001\/archotol.130.1.39","article-title":"Intraoperative molecular margin analysis in head and neck cancer","volume":"130","author":"Goldenberg","year":"2004","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"1","key":"10.1016\/j.bjoms.2007.04.015_bib13","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2144\/03351md01","article-title":"Sensitive and quantitative universal pyrosequencing methylation analysis of CpG sites","volume":"35","author":"Colella","year":"2003","journal-title":"Biotechniques"},{"issue":"4","key":"10.1016\/j.bjoms.2007.04.015_bib14","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/sj.bjc.6602972","article-title":"Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing","volume":"94","author":"Shaw","year":"2006","journal-title":"Br J Cancer"},{"issue":"11","key":"10.1016\/j.bjoms.2007.04.015_bib15","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1093\/nar\/gkl424","article-title":"Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing","volume":"34","author":"Shaw","year":"2006","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"10.1016\/j.bjoms.2007.04.015_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10266-005-0045-x","article-title":"Role of sentinel node biopsy in the management and staging of the N0 neck","volume":"93","author":"Ross","year":"2005","journal-title":"Odontology"}],"container-title":["British Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0266435607001052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0266435607001052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T17:50:33Z","timestamp":1556473833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0266435607001052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0266435607001052"],"URL":"https:\/\/doi.org\/10.1016\/j.bjoms.2007.04.015","relation":{},"ISSN":["0266-4356"],"issn-type":[{"value":"0266-4356","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}