{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T21:22:52Z","timestamp":1771190572111,"version":"3.50.1"},"reference-count":54,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["bjoms.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.bjoms.2019.06.005","type":"journal-article","created":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T08:06:43Z","timestamp":1561190803000},"page":"620-626","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Comparison of outcomes of treatment for ranula: a proportion meta-analysis"],"prefix":"10.1016","volume":"57","author":[{"given":"Y.S.","family":"Chung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.H.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjoms.2019.06.005_bib0005","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1002\/hed.21326","article-title":"Modern management and pathophysiology of ranula: literature review","volume":"32","author":"Harrison","year":"2010","journal-title":"Head Neck"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0010","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1177\/00220345560350060601","article-title":"Pathogenesis of mucoceles","volume":"35","author":"Bhaskar","year":"1956","journal-title":"J Dent Res"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0015","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/(SICI)1097-0347(199801)20:1<63::AID-HED10>3.0.CO;2-Q","article-title":"Plunging ranula: clinical observations","volume":"20","author":"Davison","year":"1998","journal-title":"Head Neck"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0020","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/hed.23324","article-title":"Ductal variation of the sublingual gland: a predisposing factor for ranula formation","volume":"36","author":"Mun","year":"2014","journal-title":"Head Neck"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0025","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1002\/lary.20291","article-title":"Oral and plunging ranulas: What is the most effective treatment?","volume":"119","author":"Patel","year":"2009","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0030","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.joms.2004.02.018","article-title":"Complications associated with surgical management of ranulas","volume":"63","author":"Zhao","year":"2005","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0035","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1136\/ebmed-2016-110401","article-title":"New evidence pyramid","volume":"21","author":"Murad","year":"2016","journal-title":"Evid Based Med"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0040","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/bmjebm-2017-110853","article-title":"Methodological quality and synthesis of case series and case reports","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0045","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.mayocp.2017.01.001","article-title":"Clinical practice guidelines: a primer on development and dissemination","volume":"92","author":"Murad","year":"2017","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0050","first-page":"557","article-title":"Clinical \u201ccase series\u201d: a concept analysis","volume":"12","author":"Abu-Zidan","year":"2012","journal-title":"Afr Health Sci"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2106\/00004623-200301000-00001","article-title":"Introducing levels of evidence to the journal","volume":"85","author":"Wright","year":"2003","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0060","unstructured":"National Heart, Lung and Blood Institute. Quality assessment tool for case series studies, 2014. Available from URL: https:\/\/www.nhbi.nih.gov\/health-topics\/study-quality-assessment-tools. Last accessed: 3 June 2019."},{"key":"10.1016\/j.bjoms.2019.06.005_bib0065","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1590\/S0102-86502013001200010","article-title":"An alternative approach to deal with the absence of clinical trials: a proportional meta-analysis of case series studies","volume":"28","author":"El Dib","year":"2013","journal-title":"Acta Cir Bras"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0070","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0075","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s11547-015-0547-8","article-title":"Effectiveness of chemotherapy and radiotherapy for laryngeal preservation in advanced laryngeal cancer: a meta-analysis and systematic review","volume":"120","author":"Luo","year":"2015","journal-title":"Radiol Med"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0080","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1756-0500-5-52","article-title":"Meta-analyses and forest plots using a microsoft excel spreadsheet: step-by-step guide focusing on descriptive data analysis","volume":"5","author":"Neyeloff","year":"2012","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0085","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ijporl.2017.04.003","article-title":"Excision of sublingual gland as treatment for ranulas in pediatric patients","volume":"97","author":"Nguyen","year":"2017","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0090","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.joms.2016.08.013","article-title":"Evaluation of OK-432 injection therapy as possible primary treatment of intraoral ranula","volume":"75","author":"Kono","year":"2017","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0095","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1007\/s00268-017-3901-2","article-title":"Ranula: current concept of pathophysiologic basis and surgical management options","volume":"41","author":"Kokong","year":"2017","journal-title":"World J Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0100","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s12663-016-0971-x","article-title":"Ranula decompression using stitch and stab method: the Aluko technique","volume":"16","author":"Aluko-Olokun","year":"2017","journal-title":"J Maxillofac Oral Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0105","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.bjoms.2015.12.017","article-title":"Anterograde excision of a sublingual gland: new surgical technique for the treatment of ranulas","volume":"54","author":"Liu","year":"2016","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0110","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.bjoms.2016.07.005","article-title":"Evolution of the management of ranulas: change in a single surgeon\u2019s practice 2001\u201314","volume":"54","author":"Hills","year":"2016","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0115","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/hed.23579","article-title":"Treatment of intraoral ranulas with micromarsupialization: clinical outcomes and safety from a phase II clinical trial","volume":"37","author":"Woo","year":"2015","journal-title":"Head Neck"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0120","doi-asserted-by":"crossref","first-page":"e223","DOI":"10.1016\/j.oooo.2015.01.007","article-title":"Treatment outcomes of the intraoral approach for a simple ranula","volume":"119","author":"Lee","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0125","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/00016489.2013.831481","article-title":"Surgical results of the intraoral approach for plunging ranula","volume":"134","author":"Yang","year":"2014","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0130","doi-asserted-by":"crossref","first-page":"e289","DOI":"10.1016\/j.oooo.2012.07.430","article-title":"Successful medical treatment for ranula in children","volume":"117","author":"Garofalo","year":"2014","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0135","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s10103-012-1176-2","article-title":"Low level laser effect after micro-marsupialization technique in treating ranulas and mucoceles: a case series report","volume":"27","author":"Amaral","year":"2012","journal-title":"Lasers Med Sci"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0140","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.ijom.2012.04.016","article-title":"Upgrading of the micro-marsupialisation technique for the management of mucus extravasation or retention phenomena","volume":"41","author":"Amaral","year":"2012","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0145","doi-asserted-by":"crossref","first-page":"e158","DOI":"10.4317\/medoral.16.e158","article-title":"Pediatric oral ranula: clinical follow-up study of 57 cases","volume":"16","author":"Bonet-Coloma","year":"2011","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0150","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1007\/s00405-011-1509-y","article-title":"Surgery for plunging ranula: the lesson not yet learned?","volume":"268","author":"Samant","year":"2011","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0155","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ijporl.2009.11.011","article-title":"Surgical management of intraoral ranulas in children: an analysis of 17 pediatric cases","volume":"74","author":"Seo","year":"2010","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0160","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/lary.20674","article-title":"Transoral approach for plunging ranula\u201410-year experience","volume":"120","author":"Huang","year":"2010","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0165","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.tripleo.2008.09.023","article-title":"Management of the pediatric plunging ranula: results of 15 years\u2019 clinical experience","volume":"107","author":"Zhi","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0170","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/j.ijporl.2008.06.003","article-title":"Primary treatment of pediatric plunging ranula with nonsurgical sclerotherapy using OK-432 (Picibanil)","volume":"72","author":"Roh","year":"2008","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0175","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1097\/SCS.0b013e31815ca1cd","article-title":"Sublingual ranula: a closer look to its surgical management","volume":"19","author":"Mortellaro","year":"2008","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0180","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.joms.2005.10.058","article-title":"Ranula: experience with 83 cases in Zimbabwe","volume":"65","author":"Chidzonga","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/01.mlg.0000191458.23867.88","article-title":"Primary treatment of ranula with intracystic injection of OK-432","volume":"116","author":"Roh","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0190","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.ijporl.2005.10.022","article-title":"Management of pediatric plunging ranula","volume":"70","author":"Mahadevan","year":"2006","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0195","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1097\/01.Mlg.0000216809.90196.83","article-title":"Treatment of ranula in pediatric patients with intralesional injection of OK-432","volume":"116","author":"Lee","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0200","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1620\/tjem.205.151","article-title":"Pediatric intraoral ranulas: an analysis of nine cases","volume":"205","author":"Yuca","year":"2005","journal-title":"Tohoku J Exp Med"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0205","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijporl.2003.09.017","article-title":"Surgical management of pediatric ranula","volume":"68","author":"Haberal","year":"2004","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0210","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0385-8146(03)00058-0","article-title":"Treatment of ranula\u2014excision of the sublingual gland versus marsupialization","volume":"30","author":"Morita","year":"2003","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0215","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00005537-200302000-00034","article-title":"Blanket removal of the sublingual gland for treatment of plunging ranula","volume":"113","author":"Kobayashi","year":"2003","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0220","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1177\/000348940311200304","article-title":"Treatment of ranula wth intracystic injection of the streptococcal preparation OK-432","volume":"112","author":"Fukase","year":"2003","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0225","doi-asserted-by":"crossref","DOI":"10.1177\/014556130308201214","article-title":"Hydrodissection for complete removal of a ranula","volume":"82","author":"Choi","year":"2003","journal-title":"Ear Nose Throat J"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0230","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1017\/S0022215100134243","article-title":"Surgical management of the plunging ranula: a review of seven cases","volume":"110","author":"Ichimura","year":"1996","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0235","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/0278-2391(94)90439-1","article-title":"Carbon dioxide laser excision and vaporization of nonplunging ranulas: a comparison of two treatment protocols","volume":"52","author":"Mintz","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0240","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1288\/00005537-198803000-00011","article-title":"Ranulas\u2014mucoceles of the oral cavity: experience in 26 children","volume":"98","author":"Crysdale","year":"1988","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0245","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/0030-4220(84)90160-9","article-title":"Plunging ranula","volume":"57","author":"McClatchey","year":"1984","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0250","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3109\/00016489.2013.847285","article-title":"OK-432 treatment of ranula extending to the parapharyngeal space","volume":"134","author":"Ohta","year":"2014","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0255","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/lary.21141","article-title":"Treatments of various otolaryngological cystic diseases by OK-4321: its indications and limitations","volume":"120","author":"Ohta","year":"2010","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0260","first-page":"1090","article-title":"OK-432 sclerotherapy of plunging ranula in 21 patients: it can be a substitute for surgery","volume":"27","author":"Rho","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0265","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.amjoto.2018.05.011","article-title":"Sublingual gland excision for the surgical management of plunging ranula","volume":"39","author":"Chen","year":"2018","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.bjoms.2019.06.005_bib0270","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s12262-011-0307-5","article-title":"Randomised clinical trials in surgery: a look at the ethical and practical issues","volume":"73","author":"Das","year":"2011","journal-title":"Indian J Surg"}],"container-title":["British Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0266435619302268?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0266435619302268?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T15:25:02Z","timestamp":1759418702000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0266435619302268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":54,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S0266435619302268"],"URL":"https:\/\/doi.org\/10.1016\/j.bjoms.2019.06.005","relation":{},"ISSN":["0266-4356"],"issn-type":[{"value":"0266-4356","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of outcomes of treatment for ranula: a proportion meta-analysis","name":"articletitle","label":"Article Title"},{"value":"British Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjoms.2019.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}