{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:13:40Z","timestamp":1792088020249,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Agency of Zhejiang Province"},{"name":"Health & Medicine Agency of Zhejiang Province"},{"name":"Science and Technology Agency of Yiwu, China","award":["2013C33176"],"award-info":[{"award-number":["2013C33176"]}]},{"name":"Science and Technology Agency of Yiwu, China","award":["2015KYB420"],"award-info":[{"award-number":["2015KYB420"]}]},{"name":"Science and Technology Agency of Yiwu, China","award":["2015-3-06"],"award-info":[{"award-number":["2015-3-06"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brazilian Journal of Otorhinolaryngology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.bjorl.2017.06.011","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T15:30:19Z","timestamp":1501774219000},"page":"545-552","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Endoscopic observation of different repair patterns in human traumatic tympanic membrane perforations"],"prefix":"10.1016","volume":"84","author":[{"given":"Peng","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuesong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Han","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjorl.2017.06.011_bib0145","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1097\/SCS.0000000000001027","article-title":"Early paper patching versus observation in patients with traumatic eardrum perforations: comparisons of anatomical and functional outcomes","volume":"25","author":"Simsek","year":"2014","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0150","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3109\/00016489.2013.857784","article-title":"A new patch material for tympanic membrane perforation by trauma: the membrane of a hen egg shell","volume":"134","author":"Jun","year":"2014","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0155","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1007\/s00405-012-2331-x","article-title":"A prospective controlled trial comparing spontaneous closure and Epifilm\u00ae patching in traumatic tympanic membrane perforations","volume":"270","author":"Sayin","year":"2013","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0160","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00405-012-1934-6","article-title":"Biocompatibility evaluation of cigarette and carbon papers used in repair of traumatic tympanic membrane perforations: experimental study","volume":"270","author":"Altunta\u015f","year":"2013","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0165","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1177\/0194599811409836","article-title":"Repair of large traumatic tympanic membrane perforation with a Steri-Strips patch","volume":"145","author":"Park","year":"2011","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0170","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1749-4486.2011.02319.x","article-title":"A randomised controlled trial comparing spontaneous healing, Gelfoam patching and edge-approximation plus Gelfoam patching in traumatic tympanic membrane perforation with inverted or everted edges","volume":"36","author":"Lou","year":"2011","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0175","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/ten.tea.2009.0476","article-title":"Tympanic membrane regeneration using a water-soluble chitosan patch","volume":"16","author":"Kim","year":"2010","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0180","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/jbm.a.32119","article-title":"Development of water-insoluble chitosan patch scaffold to repair traumatic tympanic membrane perforations","volume":"90","author":"Kim","year":"2009","journal-title":"J Biomed Mater Res A"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0185","first-page":"427","article-title":"Simple maneuver for closing traumatic eardrum perforation by micropore strip tape patching","volume":"11","author":"Saito","year":"1990","journal-title":"Am J Otol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0190","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/019459988509300217","article-title":"Traumatic perforations of the tympanic membrane: early closure with paper tape patching","volume":"93","author":"Camnitz","year":"1985","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0195","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1089\/ten.tea.2012.0053","article-title":"Scaffolds for tympanic membrane regeneration in rats","volume":"19","author":"Shen","year":"2013","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0200","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.msec.2016.11.094","article-title":"Mesenchymal stem cell-laden hybrid scaffold for regenerating subacute tympanic membrane perforation","volume":"72","author":"Jang","year":"2017","journal-title":"Mater Sci Eng C Mater Biol Appl"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0205","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1749-4486.2008.01764.x","article-title":"Determinants of spontaneous healing in traumatic perforations of the tympanic membrane","volume":"33","author":"Orji","year":"2008","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0210","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3109\/00016488709134701","article-title":"The function of migratory epidermis in the healing of tympanic membrane perforations in guinea-pig. A photographic study","volume":"103","author":"Johnson","year":"1987","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0215","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1080\/00016480410022921","article-title":"Spontaneous healing of various tympanic membrane perforations in the rat","volume":"124","author":"Wang","year":"2004","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0220","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3109\/00016488009131734","article-title":"Repair of experimental tympanic membrane perforations","volume":"90","author":"Stenfors","year":"1980","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0225","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0030-6665(20)30467-9","article-title":"Tympanic membrane wound healing. An overview","volume":"28","author":"Gladstone","year":"1995","journal-title":"Otolaryngol Clin N Am"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0230","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1006\/jsre.1999.5627","article-title":"Fibroblast response to hypoxia: the relationship between angiogenesis and matrix regulation","volume":"84","author":"Steinbrech","year":"1999","journal-title":"J Surg Res"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0235","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00129334-200701000-00013","article-title":"The role of moisture balance in wound healing","volume":"20","author":"Okan","year":"2007","journal-title":"Adv Skin Wound Care"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0240","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1097\/00006534-200009010-00012","article-title":"Accelerated healing of full-thickness skin wounds in a wet environment","volume":"106","author":"Svensj\u00f6","year":"2000","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0245","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/coa.12655","article-title":"Does chlortetracycline ointment aid healing of a traumatic tympanic membrane perforation","volume":"41","author":"Chang","year":"2016","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0250","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1258\/0022215021910483","article-title":"An observational study of the management of traumatic tympanic membrane perforations","volume":"116","author":"Amadasun","year":"2002","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0255","first-page":"1553","article-title":"Healing large traumatic eardrum perforations in humans using fibroblast growth factor applied directly or via gelfoam","volume":"33","author":"Lou","year":"2012","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0260","doi-asserted-by":"crossref","first-page":"E23","DOI":"10.1002\/lary.25715","article-title":"Comparative study on the effects of EGF and bFGF on the healing of human large traumatic perforations of the tympanic membrane","volume":"126","author":"Zhengcai-Lou","year":"2016","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0265","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/coa.12564","article-title":"The effect of ofloxacin otic drops on the regeneration of human traumatic tympanic membrane perforations","volume":"41","author":"Lou","year":"2016","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0270","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1002\/lary.20998","article-title":"Histology of the healing tympanic membrane following perforation in rats","volume":"120","author":"Santa Maria","year":"2010","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0275","first-page":"559","article-title":"Spontaneous reparation of post-traumatic tympanic perforation: an experimental study in rats","volume":"10","author":"Martini","year":"1990","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"10.1016\/j.bjorl.2017.06.011_bib0280","first-page":"802","article-title":"Cytology of repair in experimental perforation of the tympanic membrane and its relationship to chronic perforations in man","volume":"71","author":"Taylor","year":"1967","journal-title":"Trans Am Acad Ophthalmol Otolaryngol"}],"container-title":["Brazilian Journal of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1808869417301118?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1808869417301118?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T07:33:34Z","timestamp":1761723214000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1808869417301118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1808869417301118"],"URL":"https:\/\/doi.org\/10.1016\/j.bjorl.2017.06.011","relation":{},"ISSN":["1808-8694"],"issn-type":[{"value":"1808-8694","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endoscopic observation of different repair patterns in human traumatic tympanic membrane perforations","name":"articletitle","label":"Article Title"},{"value":"Brazilian Journal of Otorhinolaryngology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjorl.2017.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Associa\u00e7\u00e3o Brasileira de Otorrinolaringologia e Cirurgia C\u00e9rvico-Facial. Published by Elsevier Editora Ltda.","name":"copyright","label":"Copyright"}]}}