{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T01:35:28Z","timestamp":1773970528216,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2006,11,1]],"date-time":"2006-11-01T00:00:00Z","timestamp":1162339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"published-print":{"date-parts":[[2006,11]]},"DOI":"10.1016\/j.bjps.2005.12.047","type":"journal-article","created":{"date-parts":[[2006,5,13]],"date-time":"2006-05-13T14:22:33Z","timestamp":1147530153000},"page":"1209-1216","source":"Crossref","is-referenced-by-count":23,"title":["Treatment of human immunodeficiency virus-associated facial lipoatrophy with lipofilling and submalar silicone implants"],"prefix":"10.1016","volume":"59","author":[{"given":"A.","family":"Mori","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Lo Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Agostini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Pattarino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Vichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjps.2005.12.047_bib1","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1016\/S0140-6736(98)03391-1","article-title":"Pathogenesis of HIV-1 protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance","volume":"351","author":"Carr","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.bjps.2005.12.047_bib2","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/S0140-6736(99)06102-4","article-title":"Mitochondrial toxicity induced by nucleoside-analogue-reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy","volume":"354","author":"Brinkman","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.bjps.2005.12.047_bib3","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1016\/S0140-6736(03)14858-1","article-title":"HIV-associated adipose redistribution syndrome as a selective autonomic neuropathy","volume":"362","author":"Fliers","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.bjps.2005.12.047_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(03)00246-6","article-title":"HIV-related lipodystrophy and related factors","volume":"174","author":"Tershakovec","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bjps.2005.12.047_bib5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00001432-200402000-00005","article-title":"What is HIV-associated lipodystrophy? Defining fat distribution changes in HIV infection","volume":"17","author":"Tien","year":"2004","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.bjps.2005.12.047_bib6","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0140-6736(03)12656-6","article-title":"An objective case definition of lipodystrophy in HIV-infected adults: a case control study","volume":"361","author":"Carr","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.bjps.2005.12.047_bib7","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1086\/380790","article-title":"Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from Stavudine to Abacavir or Zidovudine: the result of the TARHEEL study","volume":"38","author":"McComsey","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjps.2005.12.047_bib8","first-page":"89","article-title":"Diagnosis and management of body morphology changes and lipid abnormalities associated with HIV infection and its therapies","volume":"12","author":"Wohl","year":"2004","journal-title":"Top HIV Med"},{"key":"10.1016\/j.bjps.2005.12.047_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00000637-200207000-00002","article-title":"Facial atrophy in HIV-related fat redistribution syndrome: anatomic evaluation and surgical reconstruction","volume":"49","author":"Talmor","year":"2002","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib10","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1097\/00006534-199906000-00042","article-title":"Anatomy of the buccal fat pad and its clinical significance","volume":"103","author":"Jackson","year":"1999","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib11","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/BF00453875","article-title":"Long-term survival of fat transplants: controlled demonstrations","volume":"19","author":"Coleman","year":"1995","journal-title":"Aesthetic Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0094-1298(20)31069-5","article-title":"Facial recontouring with lipostructure","volume":"24","author":"Coleman","year":"1997","journal-title":"Clin Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib13","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1046\/j.1524-4725.2002.02099.x","article-title":"HIV-associated facial lipoatrophy","volume":"28","author":"James","year":"2002","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib14","doi-asserted-by":"crossref","first-page":"F51","DOI":"10.1097\/00002030-199807000-00003","article-title":"A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors","volume":"12","author":"Carr","year":"1998","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib15","first-page":"595","article-title":"Body habitus alteration in HIV-infected women treated with combined antiretroviral therapy","volume":"14","author":"Ridolfo","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib16","first-page":"107","article-title":"Changes in body habitus and serum lipid abnormalities in HIV-positive women on highly active antiretroviral therapy (HAART)","volume":"21","author":"Dong","year":"1999","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.bjps.2005.12.047_bib17","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1210\/jc.84.6.1932","article-title":"Fasting hyperinsulinemia and changes in regional body composition in human immunodeficiency virus-infected women","volume":"84","author":"Hadigan","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bjps.2005.12.047_bib18","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1258\/0956462001916236","article-title":"Serum lipid levels associated with increased risk for cardiovascular disease is associated with highly active antiretroviral therapy (HAART) in HIV-1 infection","volume":"11","author":"Koppel","year":"2000","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib19","doi-asserted-by":"crossref","first-page":"786","DOI":"10.7326\/0003-4819-140-10-200405180-00008","article-title":"Metabolic effects of rosiglitazone in HIV lipodystrophy","volume":"140","author":"Hadigan","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.bjps.2005.12.047_bib20","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1086\/317426","article-title":"Impact of switching from human immunodeficiency virus type 1 protease inhibitors to efavirenz in successfully treated adults with lipodystrophy","volume":"31","author":"Martinez","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjps.2005.12.047_bib21","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1097\/00002030-199911120-00008","article-title":"Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy","volume":"13","author":"Domingo","year":"1999","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib22","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/00042560-200107010-00004","article-title":"Stavudine versus zidovudine and the development of lipodystrophy","volume":"27","author":"Bogner","year":"2001","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"30","key":"10.1016\/j.bjps.2005.12.047_bib23","doi-asserted-by":"crossref","first-page":"28220","DOI":"10.1074\/jbc.M302297200","article-title":"Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property","volume":"278","author":"Papucci","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bjps.2005.12.047_bib24","first-page":"1946","article-title":"Flat cheeks. Polyethylene endoprostheses inserted subperiosteally along the zygomatic arch","volume":"58","author":"Spadafora","year":"1971","journal-title":"Prensa Med Argent"},{"issue":"No 1","key":"10.1016\/j.bjps.2005.12.047_bib25","article-title":"Profileplasty","volume":"Card 1","author":"Hinderer","year":"1971","journal-title":"Int Micrform J Aesthet Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00006534-197508000-00007","article-title":"Malar implants for improvement of facial appearance","volume":"56","author":"Hinderer","year":"1975","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1055\/s-2001-16367","article-title":"Augmentation of the cheeks, chin and pre-jowl sulcus, and nasolabial folds","volume":"17","author":"Romo","year":"2001","journal-title":"Facial Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib28","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1111\/j.1524-4725.2004.30175.x","article-title":"A case of HIV-associated facial lipoatrophy treated with 1000-cs liquid injectable silicone","volume":"30","author":"Orentreich","year":"2004","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib29","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1097\/00002030-200311210-00009","article-title":"Polylactic acid implants (New-Fill)\u00ae to correct facial lipoatrophy in HIV-infected patients: results of the open-label study VEGA","volume":"17","author":"Valantine","year":"2003","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib30","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1097\/00002030-200311210-00018","article-title":"Polylactic acid implants. A new smile for lipoatrophic faces?","volume":"17","author":"Boix","year":"2003","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib31","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0294-1260(02)00176-0","article-title":"Surgical treatment of facial lipoatrophy","volume":"48","author":"Caye","year":"2003","journal-title":"Ann Chir Plast Esthet"},{"key":"10.1016\/j.bjps.2005.12.047_bib32","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1097\/01.PRS.0000097288.27152.38","article-title":"Treatment of human immunodeficiency virus-associated lipodystrophy with dermafat graft transfer to the malar area","volume":"113","author":"Strauch","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib33","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/00000637-200107000-00027","article-title":"Dermis\u2013fat graft for facial lipodystrophy in HIV-positive patients: is a worthwhile?","volume":"47","author":"Wechselberger","year":"2001","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib34","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1097\/00002030-200209270-00026","article-title":"Correction of facial lipoatrophy in HIV-infected patients on highly active antiretroviral therapy by injection of autologous fatty tissue","volume":"16","author":"Levan","year":"2002","journal-title":"AIDS"},{"key":"10.1016\/j.bjps.2005.12.047_bib35","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1086\/426686","article-title":"Facial lipohypertrophy in HIV-infected subjects who underwent autologous fat tissue transplantation","volume":"40","author":"Gueraldi","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bjps.2005.12.047_bib36","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/0007-1226(74)90069-1","article-title":"Transoral silastic augmentation of the malar region","volume":"27","author":"Jabaley","year":"1974","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib37","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1001\/archotol.125.9.980","article-title":"Malar augmentation. A 5-year retrospective review of the silastic midfacial malar implant","volume":"125","author":"Metzinger","year":"1999","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib38","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0094-1298(20)30671-4","article-title":"Alloplastic cheek augmentation","volume":"18","author":"Mladick","year":"1991","journal-title":"Clin Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib39","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1097\/00006534-198305000-00011","article-title":"Complications in aesthetic malar augmentation","volume":"71","author":"Wilkinson","year":"1983","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib40","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/00006534-199507000-00009","article-title":"Malar augmentation with silicone implants","volume":"96","author":"Ivy","year":"1995","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib41","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/00000637-198803000-00003","article-title":"A new approach to evaluation and surgery of the malar complex","volume":"20","author":"Powell","year":"1988","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib42","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1001\/archotol.1989.01860320074022","article-title":"Malar augmentation. Patient classification and placement","volume":"115","author":"Prendergast","year":"1989","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib43","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1055\/s-2008-1064643","article-title":"Malar augmentation","volume":"3","author":"Silver","year":"1992","journal-title":"Facial Plast Surg"},{"key":"10.1016\/j.bjps.2005.12.047_bib44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1055\/s-2000-7324","article-title":"Malar, submalar, and midfacial implants","volume":"16","author":"Costantinides","year":"2000","journal-title":"Facial Plast Surg"}],"container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681506002610?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681506002610?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T06:17:03Z","timestamp":1627366623000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1748681506002610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11]]},"references-count":44,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["S1748681506002610"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2005.12.047","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2006,11]]}}}