{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:57:21Z","timestamp":1792738641116,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2020R1A2C2009496"],"award-info":[{"award-number":["2020R1A2C2009496"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jprasurg.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.bjps.2022.12.002","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T20:34:17Z","timestamp":1671654857000},"page":"379-387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Efficacy and safety of transarterial bleomycin sclerotherapy of early-stage facial arteriovenous malformation: Single-center multidisciplinary team experience"],"prefix":"10.1016","volume":"77","author":[{"given":"Sang Yub","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Sun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongmin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok Jong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung","family":"Huh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Yoon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7359-3044","authenticated-orcid":false,"given":"Ho Yun","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bjps.2022.12.002_bib0001","series-title":"Vascular birthmarks: hemangiomas and malformations","first-page":"228","article-title":"Arteriovenous malformations","author":"Young","year":"1988"},{"key":"10.1016\/j.bjps.2022.12.002_bib0002","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1097\/00006534-199809010-00006","article-title":"Arteriovenous malformations of the head and neck: Natural history and management","volume":"102","author":"Kohout","year":"1998","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0003","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/DSS.0000000000000993","article-title":"Clinical characteristics of arteriovenous malformations of the head and neck","volume":"43","author":"Kim","year":"2017","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0004","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3174\/ajnr.A3180","article-title":"Head and neck arteriovenous malformations: Results of ethanol sclerotherapy","volume":"34","author":"Pekkola","year":"2013","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0005","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1007\/s00270-017-1855-2","article-title":"Polidocanol sclerotherapy combined with transarterial embolization using n-butyl cyanoacrylate for extracranial arteriovenous malformations","volume":"41","author":"Kitagawa","year":"2018","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0006","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/1097-0142(1967)20:5<891::AID-CNCR2820200550>3.0.CO;2-V","article-title":"Studies on bleomycin","volume":"20","author":"Umezawa","year":"1967","journal-title":"Cancer"},{"key":"10.1016\/j.bjps.2022.12.002_bib0007","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3109\/2000656X.2014.951051","article-title":"Intralesional bleomycin injection in management of low flow vascular malformations in children","volume":"49","author":"Mohan","year":"2015","journal-title":"J Plast Surg Hand Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0008","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1007\/s00270-014-0932-z","article-title":"Safety and efficacy of bleomycin sclerotherapy for microcystic lymphatic malformation","volume":"37","author":"Chaudry","year":"2014","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0009","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/0196-0709(95)90149-3","article-title":"Bleomycin sclerotherapy in patients with congenital lymphatic malformation in the head and neck","volume":"16","author":"Sung","year":"1995","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0010","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1148\/radiol.2017162076","article-title":"Treatment of early-stage extracranial arteriovenous malformations with intralesional interstitial bleomycin injection: A pilot study","volume":"287","author":"Jin","year":"2018","journal-title":"Radiology"},{"key":"10.1016\/j.bjps.2022.12.002_bib0011","first-page":"9","article-title":"Consensus document of the International Union of Angiology (IUA)-2013. Current concept on the management of arterio-venous management","volume":"32","author":"Lee","year":"2013","journal-title":"Int Angiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0012","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.jvir.2015.05.007","article-title":"Bleomycin foam treatment of venous malformations: A promising agent for effective treatment with minimal swelling","volume":"26","author":"Ul Haq","year":"2015","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0013","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/S0022-3468(83)80043-8","article-title":"Congenital vascular lesions: Clinical application of a new classification","volume":"18","author":"Finn","year":"1983","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0014","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1583\/05-1769.1","article-title":"Arteriovenous malformations of the body and extremities: Analysis of therapeutic outcomes and approaches according to a modified angiographic classification","volume":"13","author":"Cho","year":"2006","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.bjps.2022.12.002_bib0015","doi-asserted-by":"crossref","first-page":"S199","DOI":"10.1097\/01.RVI.0000094584.83406.3e","article-title":"Society of Interventional Radiology clinical practice guidelines","volume":"14","author":"Sacks","year":"2003","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2019.08.286","article-title":"Ethanol embolization of lingual arteriovenous malformations: Positive experience in 52 patients during 11 years","volume":"72","author":"Zheng","year":"2020","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0017","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0027-5107(90)90110-P","article-title":"The kinetics of DNA damage by bleomycin in mammalian cells","volume":"232","author":"Lopez-Larraza","year":"1990","journal-title":"Mutat Res"},{"key":"10.1016\/j.bjps.2022.12.002_bib0018","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1002\/1097-0142(197304)31:4<903::AID-CNCR2820310422>3.0.CO;2-N","article-title":"A clinical review of bleomycin: A new antineoplastic agent","volume":"31","author":"Blum","year":"1973","journal-title":"Cancer"},{"key":"10.1016\/j.bjps.2022.12.002_bib0019","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1097\/PRS.0b013e31820e923c","article-title":"Intralesional bleomycin injection treatment for vascular birthmarks: A 5-year experience at a single United Kingdom unit","volume":"127","author":"Sainsbury","year":"2011","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0020","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/SAP.0b013e31824e298d","article-title":"Noninvasive management of hemangioma and vascular malformation using intralesional bleomycin injection","volume":"70","author":"Hassan","year":"2013","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0021","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1590\/abd1806-4841.20175851","article-title":"Vascular sclerosing effects of bleomycin on cutaneous veins: A pharmacopathologic study on experimental animals","volume":"92","author":"AlGhamdi","year":"2017","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0022","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1017\/cjn.2020.178","article-title":"Bleomycin for head and neck venolymphatic malformations: A systematic review","volume":"48","author":"Finitsis","year":"2021","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.bjps.2022.12.002_bib0023","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.bjps.2019.05.034","article-title":"Effect of foam and liquid bleomycin in the management of venous malformations in head and neck region: A comparative study","volume":"73","author":"Helal","year":"2020","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.bjps.2022.12.002_bib0024","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/ppul.21139","article-title":"Acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation","volume":"45","author":"Atwa","year":"2010","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0025","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s00270-020-02420-w","article-title":"Fatal lung toxicity after intralesional bleomycin sclerotherapy of a vascular malformation","volume":"43","author":"Cho","year":"2020","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.bjps.2022.12.002_bib0026","first-page":"141","article-title":"Acute lung toxicity after intralesional bleomycin sclerotherapy","author":"Mendez-Echevarria","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.bjps.2022.12.002_bib0027","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3892\/etm.2013.1144","article-title":"Comparison between absolute ethanol and bleomycin for the treatment of venous malformation in children","volume":"6","author":"Zhang","year":"2013","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.bjps.2022.12.002_bib0028","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1007\/s00270-022-03224-w","article-title":"Safety and efficacy of bleomycin slow infusion sclerotherapy using a syringe pump for microcystic and mixed lymphatic malformations","volume":"45","author":"Cha","year":"2022","journal-title":"Cardiovasc Intervent Radiol"}],"container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174868152200701X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174868152200701X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T20:49:16Z","timestamp":1761684556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S174868152200701X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":28,"alternative-id":["S174868152200701X"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2022.12.002","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of transarterial bleomycin sclerotherapy of early-stage facial arteriovenous malformation: Single-center multidisciplinary team experience","name":"articletitle","label":"Article Title"},{"value":"Journal of Plastic, Reconstructive & Aesthetic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjps.2022.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}