{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:17:06Z","timestamp":1783426626840,"version":"3.54.6"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jprasurg.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bjps.2025.10.014","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:28:26Z","timestamp":1760804906000},"page":"245-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Efficacy and safety of onabotulinumtoxin A in the treatment of platysma prominence: A systematic review and meta-analysis of randomized clinical trials"],"prefix":"10.1016","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7366-1550","authenticated-orcid":false,"given":"Ofonime Chantal","family":"Udoma-Udofa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9025-1586","authenticated-orcid":false,"given":"Luiz F\u00e1bio Silva","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7305-4362","authenticated-orcid":false,"given":"Lucas Rezende","family":"de Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Alves","family":"de Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00edsa de Souza","family":"Borges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0671-216X","authenticated-orcid":false,"given":"Tau\u00e3na Terra Cordeiro","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9022-4925","authenticated-orcid":false,"given":"Divya","family":"Rajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2954-0628","authenticated-orcid":false,"given":"Lucas","family":"Kreutz-Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.bjps.2025.10.014_bib1","doi-asserted-by":"crossref","first-page":"80S","DOI":"10.1097\/PRS.0000000000001841","article-title":"Neurotoxins: current concepts in cosmetic use on the face and neck--Jawline contouring\/platysma bands\/necklace lines","volume":"136","author":"Levy","year":"2015","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2025.10.014_bib2","series-title":"Botulinum toxins: cosmetic and clinical applications","first-page":"199","article-title":"Neck rejuvenation","author":"De Boulle","year":"2017"},{"issue":"8","key":"10.1016\/j.bjps.2025.10.014_bib3","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1097\/DSS.0000000000001135","article-title":"The facial platysma and its underappreciated role in lower face dynamics and contour","volume":"43","author":"de Almeida","year":"2017","journal-title":"Dermatol Surg"},{"issue":"9","key":"10.1016\/j.bjps.2025.10.014_bib4","first-page":"931","article-title":"Botulinum toxin-A chemical denervation for platysmal bands: maximal dosing considerations","volume":"14","author":"Chen","year":"2015","journal-title":"J Drugs Dermatol"},{"issue":"6","key":"10.1016\/j.bjps.2025.10.014_bib5","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.clindermatol.2003.11.004","article-title":"Botulinum toxin for rejuvenation of the neck","volume":"21","author":"Brandt","year":"2003","journal-title":"Clin Dermatol"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib6","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/asj\/sjae220","article-title":"Improving neck and jawline aesthetics with onabotulinumtoxinA by minimizing platysma muscle contraction effects: efficacy and safety results in a phase 3 randomized, placebo-controlled study","volume":"45","author":"Shridharani","year":"2025","journal-title":"Aesthet Surg J"},{"issue":"5","key":"10.1016\/j.bjps.2025.10.014_bib7","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1007\/s00266-011-9782-0","article-title":"Closed platysmotomy: a new procedure for the treatment of platysma bands without skin dissection","volume":"35","author":"Daher","year":"2011","journal-title":"Aesthet Plast Surg"},{"issue":"10","key":"10.1016\/j.bjps.2025.10.014_bib8","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/asj\/sjaa339","article-title":"The facial aging process from the \u201cInside Out\u201d","volume":"41","author":"Swift","year":"2021","journal-title":"Aesthet Surg J"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1053\/sder.2001.25139","article-title":"BOTOX use in the mid and lower face and neck","volume":"20","author":"Carruthers","year":"2001","journal-title":"Semin Cutan Med Surg"},{"issue":"1","key":"10.1016\/j.bjps.2025.10.014_bib10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/jocd.12128","article-title":"Facial dynamics and emotional expressions in facial aging treatments","volume":"14","author":"Michaud","year":"2015","journal-title":"J Cosmet Dermatol"},{"issue":"1","key":"10.1016\/j.bjps.2025.10.014_bib11","doi-asserted-by":"crossref","first-page":"NP1","DOI":"10.1093\/asj\/sjz207","article-title":"Landmarks in facial rejuvenation surgery: the top 50 most cited articles","volume":"40","author":"Kreutz-Rodrigues","year":"2020","journal-title":"Aesthet Surg J"},{"issue":"10","key":"10.1016\/j.bjps.2025.10.014_bib12","article-title":"A systematic review and comparative analysis of reconstructive rhytidectomy: advantages, disadvantages, and patient outcomes","volume":"16","author":"Meretsky","year":"2024","journal-title":"Cureus"},{"issue":"S1","key":"10.1016\/j.bjps.2025.10.014_bib13","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000032372","article-title":"Botox (onabotulinumtoxinA) mechanism of action","volume":"102","author":"Brin","year":"2023","journal-title":"Medicine"},{"key":"10.1016\/j.bjps.2025.10.014_bib14","series-title":"Cochrane handbook for systematic reviews of interventions","author":"Higgins","year":"2023"},{"key":"10.1016\/j.bjps.2025.10.014_bib15","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.bjps.2025.10.014_bib16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/PRS.0000000000011472","article-title":"Efficacy and safety of onabotulinumtoxinA for the treatment of platysma prominence: a randomized phase 2 dose-ranging study","volume":"155","author":"Rohrich","year":"2025","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib17","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jaad.2024.10.027","article-title":"Improvement of platysma prominence with onabotulinumtoxinA: safety and efficacy results from a randomized, double-blinded, placebo-controlled phase 3 trial","volume":"92","author":"Fabi","year":"2025","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.bjps.2025.10.014_bib18","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The cochrane collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib19","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000006490","article-title":"Platysma prominence: review and expert analysis of clinical presentation, burden, and treatment considerations","volume":"13","author":"Trindade de Almeida","year":"2025","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.bjps.2025.10.014_bib20","doi-asserted-by":"crossref","DOI":"10.1093\/asjof\/ojac034","article-title":"Creating lift in the lower face with botulinum toxin A treatment: an anatomical overview with videos and case studies illustrating patient evaluation and treatment","volume":"4","author":"Lorenc","year":"2022","journal-title":"Aesthet Surg J Open Forum"},{"issue":"6","key":"10.1016\/j.bjps.2025.10.014_bib21","doi-asserted-by":"crossref","first-page":"S330","DOI":"10.1016\/j.jval.2023.03.1878","article-title":"PCR100 development and validation of patient-reported outcome measures for platysma prominence","volume":"26","author":"Garcia","year":"2023","journal-title":"Value Health"},{"issue":"11","key":"10.1016\/j.bjps.2025.10.014_bib22","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1111\/j.1524-4725.1998.tb04103.x","article-title":"Cosmetic use of botulinum A exotoxin for the aging neck","volume":"24","author":"Brandt","year":"1998","journal-title":"Dermatol Surg"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib23","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1097\/00006534-199902000-00043","article-title":"Botulinum A exotoxin for the management of platysma bands","volume":"103","author":"Matarasso","year":"1999","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"10.1016\/j.bjps.2025.10.014_bib24","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1093\/asj\/sjy179","article-title":"Botulinum toxin treatment for mild to moderate platysma bands: a systematic review of efficacy, safety, and injection technique","volume":"39","author":"Sugrue","year":"2019","journal-title":"Aesthet Surg J"},{"issue":"1","key":"10.1016\/j.bjps.2025.10.014_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsc.2004.04.008","article-title":"Complications of botulinum toxin A use in facial rejuvenation","volume":"13","author":"Vartanian","year":"2005","journal-title":"Facial Plast Surg Clin N Am"},{"issue":"6","key":"10.1016\/j.bjps.2025.10.014_bib26","article-title":"Effective treatment of platysma bands with neurotoxin","volume":"8","author":"Rohrich","year":"2020","journal-title":"Plast Reconstr Surg Glob Open"}],"container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681525005972?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681525005972?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T11:35:59Z","timestamp":1783424159000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1748681525005972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":26,"alternative-id":["S1748681525005972"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2025.10.014","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of onabotulinumtoxin A in the treatment of platysma prominence: A systematic review and meta-analysis of randomized clinical trials","name":"articletitle","label":"Article Title"},{"value":"Journal of Plastic, Reconstructive & Aesthetic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjps.2025.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}