{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:46:33Z","timestamp":1790621193208,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jprasurg.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.bjps.2026.01.010","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T16:24:19Z","timestamp":1768494259000},"page":"186-195","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Recent preoperative opioid prescription is associated with increased complications after microsurgical breast reconstruction"],"prefix":"10.1016","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5691-519X","authenticated-orcid":false,"given":"Patricia M.","family":"Fuentes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8278-1259","authenticated-orcid":false,"given":"Matthew Q.","family":"Dao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-6874","authenticated-orcid":false,"given":"Emma","family":"Lascar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheuli","family":"Chowdhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernice","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery","family":"Russell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Taub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8392-7180","authenticated-orcid":false,"given":"Peter W.","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bjps.2026.01.010_bib1","first-page":"216","article-title":"Breast cancer pain management - a review of current & novel therapies","volume":"139","author":"Satija","year":"2014","journal-title":"Indian J Med Res"},{"issue":"9930","key":"10.1016\/j.bjps.2026.01.010_bib2","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/S0140-6736(13)62416-2","article-title":"Early palliative care for patients with advanced cancer: a cluster-randomised controlled trial","volume":"383","author":"Zimmermann","year":"2014","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.bjps.2026.01.010_bib3","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1001\/jama.2009.1198","article-title":"Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: the Project ENABLE II randomized controlled trial","volume":"302","author":"Bakitas","year":"2009","journal-title":"JAMA"},{"issue":"13","key":"10.1016\/j.bjps.2026.01.010_bib4","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1200\/JCO.2014.58.6362","article-title":"Early versus delayed initiation of concurrent palliative oncology care: Patient outcomes in the ENABLE III randomized controlled trial","volume":"33","author":"Bakitas","year":"2015","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"issue":"5","key":"10.1016\/j.bjps.2026.01.010_bib5","doi-asserted-by":"crossref","first-page":"331","DOI":"10.6004\/jnccn.2024.0035","article-title":"Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology","volume":"22","author":"Gradishar","year":"2024","journal-title":"J Natl Compr Cancer Netw"},{"issue":"3","key":"10.1016\/j.bjps.2026.01.010_bib6","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/SAP.0000000000002664","article-title":"Autologous breast reconstruction trends in the United States: using the nationwide inpatient sample database","volume":"87","author":"Masoomi","year":"2021","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib7","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.bjps.2022.11.044","article-title":"Implant vs. autologous tissue-based breast reconstruction: a systematic review and meta-analysis of the studies comparing surgical approaches in 55,455 patients","volume":"77","author":"Stefura","year":"2023","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fpain.2023.1182488","article-title":"Pain associated with breast cancer: etiologies and therapies","volume":"4","author":"Doan","year":"2023","journal-title":"Front Pain Res"},{"issue":"6","key":"10.1016\/j.bjps.2026.01.010_bib9","first-page":"477","article-title":"Breast cancer statistics 2024","volume":"74","author":"Giaquinto","year":"2024","journal-title":"CA Cancer J Clin"},{"issue":"4","key":"10.1016\/j.bjps.2026.01.010_bib10","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1097\/SLA.0000000000001901","article-title":"Preoperative opioid use is independently associated with increased costs and worse outcomes after major abdominal surgery","volume":"265","author":"Cron","year":"2017","journal-title":"Ann Surg"},{"issue":"10","key":"10.1016\/j.bjps.2026.01.010_bib11","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2106\/JBJS.16.01200","article-title":"Impact of preoperative opioid use on total knee arthroplasty outcomes","volume":"99","author":"Smith","year":"2017","journal-title":"JBJS"},{"issue":"2","key":"10.1016\/j.bjps.2026.01.010_bib12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3171\/2016.7.SPINE16284","article-title":"Prediction based on preoperative opioid use of clinical outcomes after transforaminal lumbar interbody fusions","volume":"26","author":"Villavicencio","year":"2017","journal-title":"J Neurosurg Spine"},{"issue":"3","key":"10.1016\/j.bjps.2026.01.010_bib13","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/PRS.0000000000004636","article-title":"Opioid use following outpatient breast surgery: are physicians part of the problem?","volume":"142","author":"Hart","year":"2018","journal-title":"Plast Reconstr Surg"},{"issue":"12","key":"10.1016\/j.bjps.2026.01.010_bib14","doi-asserted-by":"crossref","first-page":"7823","DOI":"10.1245\/s10434-021-10023-z","article-title":"Perioperative inpatient opioid consumption following autologous free-flap breast reconstruction patients: an examination of risk and patient-reported outcomes","volume":"28","author":"Nelson","year":"2021","journal-title":"Ann Surg Oncol"},{"issue":"4","key":"10.1016\/j.bjps.2026.01.010_bib15","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000006694","article-title":"Regional anesthesia and postoperative opioid use in autologous breast reconstruction: a systematic review and meta-analysis","volume":"13","author":"Heron","year":"2025","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.bjps.2026.01.010_bib16","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bjps.2023.05.007","article-title":"Association of preoperative opioid use and postoperative complications following breast reconstruction","volume":"83","author":"Cheah","year":"2023","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"3","key":"10.1016\/j.bjps.2026.01.010_bib17","doi-asserted-by":"crossref","DOI":"10.1177\/23259671221077933","article-title":"Effect of perioperative opioid use on patients undergoing hip arthroscopy","volume":"10","author":"Rogers","year":"2022","journal-title":"Orthop J Sports Med"},{"issue":"7","key":"10.1016\/j.bjps.2026.01.010_bib18","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1177\/15589447231160206","article-title":"Risks of chronic preoperative opioid use on distal radius surgery outcomes","volume":"19","author":"Newton","year":"2024","journal-title":"Hand"},{"issue":"9","key":"10.1016\/j.bjps.2026.01.010_bib19","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1093\/asj\/sjad117","article-title":"Opioid-prescribing patterns in body contouring surgery","volume":"43","author":"Mundra","year":"2023","journal-title":"Aesthet Surg J"},{"issue":"3","key":"10.1016\/j.bjps.2026.01.010_bib20","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/bjaed\/mkw030","article-title":"Antinociceptive and immunosuppressive effect of opioids in an acute postoperative setting: an evidence-based review","volume":"17","author":"Ramaswamy","year":"2017","journal-title":"BJA Educ"},{"issue":"4","key":"10.1016\/j.bjps.2026.01.010_bib21","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1055\/s-0040-1716846","article-title":"A meta-analysis of autologous microsurgical breast reconstruction and timing of adjuvant radiation therapy","volume":"37","author":"Heiman","year":"2021","journal-title":"J Reconstr Microsurg"},{"issue":"2","key":"10.1016\/j.bjps.2026.01.010_bib22","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/SLA.0000000000001177","article-title":"Complications after mastectomy and immediate breast reconstruction for breast cancer: a claims-based analysis","volume":"263","author":"Jagsi","year":"2016","journal-title":"Ann Surg"},{"issue":"1","key":"10.1016\/j.bjps.2026.01.010_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0190362","article-title":"Prescription opioids are associated with higher mortality in patients diagnosed with sepsis: a retrospective cohort study using electronic health records","volume":"13","author":"Zhang","year":"2018","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.bjps.2026.01.010_bib24","first-page":"5","article-title":"Opioid system modulates the immune function: a review","volume":"1","author":"Liang","year":"2016","journal-title":"Transl Perioper Pain Med"},{"issue":"4","key":"10.1016\/j.bjps.2026.01.010_bib25","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/s11481-011-9292-5","article-title":"Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections","volume":"6","author":"Roy","year":"2011","journal-title":"J Neuroimmune Pharmacol Off J Soc Neuroimmune Pharmacol"},{"issue":"1","key":"10.1016\/j.bjps.2026.01.010_bib26","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/PRS.0000000000010188","article-title":"Extended venous thromboembolism chemoprophylaxis following microsurgical breast reconstruction: analysis of trends in postoperative anticoagulation","volume":"152","author":"Le","year":"2023","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinsp.2023.100229","article-title":"Venous thromboembolism incidence in postoperative breast cancer patients","volume":"78","author":"Maesaka","year":"2023","journal-title":"Clinics"},{"key":"10.1016\/j.bjps.2026.01.010_bib28","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bjps.2024.05.003","article-title":"Contributors to post-operative venous thromboembolism risk after breast cancer surgery: a systematic review and meta-analysis","volume":"94","author":"Ahmed","year":"2024","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib29","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11239-015-1311-6","article-title":"The epidemiology of venous thromboembolism","volume":"41","author":"Heit","year":"2016","journal-title":"J Thromb Thrombolysis"},{"issue":"1\u20132","key":"10.1016\/j.bjps.2026.01.010_bib30","first-page":"9","article-title":"A review on hematological factors in opioid-dependent people (opium and heroin) after the withdrawal period","volume":"2","author":"Haghpanah","year":"2010","journal-title":"Addict Health"},{"issue":"4","key":"10.1016\/j.bjps.2026.01.010_bib31","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/SAP.0b013e3182a0df25","article-title":"Predictors of readmission after breast reconstruction: a multi-institutional analysis of 5012 patients","volume":"71","author":"Mlodinow","year":"2013","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib32","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12877-021-02101-4","article-title":"Frailty status as a potential factor in increased postoperative opioid use in older adults","volume":"21","author":"Auckley","year":"2021","journal-title":"BMC Geriatr"},{"issue":"2","key":"10.1016\/j.bjps.2026.01.010_bib33","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.amjsurg.2018.11.020","article-title":"Impact of frailty on outcomes in surgical patients: a systematic review and meta-analysis","volume":"218","author":"Panayi","year":"2019","journal-title":"Am J Surg"},{"issue":"9","key":"10.1016\/j.bjps.2026.01.010_bib34","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1016\/j.bjps.2022.04.035","article-title":"The modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: an analysis of 40,415 cases","volume":"75","author":"Panayi","year":"2022","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.bjps.2026.01.010_bib35","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.bjps.2023.06.040","article-title":"Frailty among patients undergoing breast reconstruction surgery: a systematic review and meta-analysis","volume":"84","author":"Shafiee","year":"2023","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"5","key":"10.1016\/j.bjps.2026.01.010_bib36","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1097\/PRS.0000000000010069","article-title":"Decreasing opioids in outpatient breast surgery with an enhanced recovery after surgery program and preoperative education","volume":"151","author":"Wong","year":"2023","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"10.1016\/j.bjps.2026.01.010_bib37","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1177\/22925503241234935","article-title":"Enhanced recovery after surgery in immediate DIEP flap breast reconstruction: reducing length of stay and opioid use","volume":"33","author":"El-Jebaoui","year":"2024","journal-title":"Plast Surg"},{"issue":"11","key":"10.1016\/j.bjps.2026.01.010_bib38","article-title":"Erector spinae plane block decreases pain and opioid consumption in breast surgery: systematic review","volume":"7","author":"ElHawary","year":"2019","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"9","key":"10.1016\/j.bjps.2026.01.010_bib39","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1245\/s10434-020-08432-7","article-title":"Opioid consumption following breast surgery decreases with a brief educational intervention: a randomized, controlled trial","volume":"27","author":"Egan","year":"2020","journal-title":"Ann Surg Oncol"},{"issue":"11","key":"10.1016\/j.bjps.2026.01.010_bib40","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000003932","article-title":"Opioid-sparing strategies in alloplastic breast reconstruction: a systematic review","volume":"9","author":"Crystal","year":"2021","journal-title":"Plast Reconstr Surg Glob Open"}],"container-title":["Journal of Plastic, Reconstructive & Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681526000227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681526000227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:17:07Z","timestamp":1778080627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1748681526000227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":40,"alternative-id":["S1748681526000227"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2026.01.010","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recent preoperative opioid prescription is associated with increased complications after microsurgical breast reconstruction","name":"articletitle","label":"Article Title"},{"value":"Journal of Plastic, Reconstructive & Aesthetic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjps.2026.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.","name":"copyright","label":"Copyright"}]}}