{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T12:05:18Z","timestamp":1779537918332,"version":"3.53.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jprasurg.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bjps.2026.03.028","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:46:22Z","timestamp":1773852382000},"page":"288-296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Keloid may be a modern inflammatory disease: A historical and clinicopathological perspective"],"prefix":"10.1016","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3658-555X","authenticated-orcid":false,"given":"Rei","family":"Ogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangpeng","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Ai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.bjps.2026.03.028_bib1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3390\/ijms18030606","article-title":"Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis","volume":"18","author":"Ogawa","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.bjps.2026.03.028_bib2","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000004084","article-title":"Role of skin stretch on local vascular permeability in murine and cell culture models","volume":"10","author":"Demir","year":"2022","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.bjps.2026.03.028_bib3","series-title":"Textbook on scar management: state of the art management and emerging technologies","article-title":"The epidemiology of keloids","author":"Huang","year":"2020"},{"issue":"12","key":"10.1016\/j.bjps.2026.03.028_bib4","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000006366","article-title":"Vascular basement membrane fragmentation in keloids and the expression of key basement membrane component genes","volume":"12","author":"Saijo","year":"2024","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"2","key":"10.1016\/j.bjps.2026.03.028_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/wrr.70015","article-title":"Comprehensive analysis of keloid vasculature by tissue clearing and 3D imaging","volume":"33","author":"Nguyen","year":"2025","journal-title":"Wound Repair Regen"},{"issue":"6","key":"10.1016\/j.bjps.2026.03.028_bib6","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/wrr.12601","article-title":"Endothelial dysfunction may promote keloid growth","volume":"25","author":"Noishiki","year":"2017","journal-title":"Wound Repair Regen"},{"issue":"4","key":"10.1016\/j.bjps.2026.03.028_bib7","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1097\/00006534-197510000-00019","article-title":"Presumptive evidence of the effect of pregnancy estrogens on keloid growth: case report","volume":"56","author":"Moustafa MF","year":"1975","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"10.1016\/j.bjps.2026.03.028_bib8","doi-asserted-by":"crossref","DOI":"10.1097\/GOX.0000000000004374","article-title":"Hemodynamics and vascular histology of keloid tissues and anatomy of nearby blood vessels","volume":"10","author":"Eura","year":"2022","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"1","key":"10.1016\/j.bjps.2026.03.028_bib9","first-page":"85","article-title":"Identifying the practice of tattooing in ancient Egypt and Nubia","volume":"14","author":"Tassie","year":"2003","journal-title":"Pap Inst Archaeol"},{"key":"10.1016\/j.bjps.2026.03.028_bib10","unstructured":"Legge M. Body modification segment: the archaeology of scarification. Available at: \u3008https:\/\/cushareejournal.wordpress.com\/2019\/04\/13\/body-modification-segment-the-archaeology-of-scarification\/\u3009. [Accessed January 22, 2026]."},{"key":"10.1016\/j.bjps.2026.03.028_bib11","unstructured":"Hager N. Running horned woman, Tassili n\u2032Ajjer, Algeria. Smarthistory. Available at: \u3008https:\/\/smarthistory.org\/running-horned-woman-tassili-najjer-algeria\/\u3009. [Accessed January 22, 2026]."},{"key":"10.1016\/j.bjps.2026.03.028_bib12","unstructured":"Walters Art Museum. Earthenware figurine from the Coahuayana River Valley. Available at: \u3008https:\/\/art.thewalters.org\/object\/2009.20.53\/\u3009. [Accessed January 22, 2026]."},{"issue":"3","key":"10.1016\/j.bjps.2026.03.028_bib13","first-page":"271","article-title":"The Edwin Smith surgical papyrus and the diagnosis and treatment of injuries to the skull and spine 5000 years ago","volume":"3","author":"Elsberg","year":"1931","journal-title":"Ann Med Hist"},{"key":"10.1016\/j.bjps.2026.03.028_bib14","series-title":"The Edwin Smith surgical papyrus: hieroglyphic text translation and commentary","first-page":"403","article-title":"Bulging tumors on the breast","author":"Breasted","year":"1930"},{"key":"10.1016\/j.bjps.2026.03.028_bib15","series-title":"Western Zhou bronze inscriptions","author":"Puglia","year":"2024"},{"key":"10.1016\/j.bjps.2026.03.028_bib16","series-title":"Translation and study","article-title":"Early Chinese medical literature: the Mawangdui medical manuscripts","author":"Harper","year":"1998"},{"key":"10.1016\/j.bjps.2026.03.028_bib17","series-title":"Classified compilation of ancient Chinese characters","author":"Gao","year":"2008"},{"key":"10.1016\/j.bjps.2026.03.028_bib18","series-title":"Su\u015bruta-Sa\u1e43hit\u0101: with english translation of text and Dalha\u1e47a\u2019s commentary along with critical notes","volume":"vol. 1","year":"2014"},{"key":"10.1016\/j.bjps.2026.03.028_bib19","series-title":"Hippocratic writings. Translated by\u00a0Chadwick J, Mann WN","year":"1983"},{"key":"10.1016\/j.bjps.2026.03.028_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7092151","article-title":"Vascular inflammation and oxidative stress: major triggers for cardiovascular disease","volume":"2019","author":"Steven","year":"2019","journal-title":"Oxid Med Cell Longev"},{"issue":"3","key":"10.1016\/j.bjps.2026.03.028_bib21","doi-asserted-by":"crossref","DOI":"10.1097\/AS9.0000000000000482","article-title":"The surgery of Celsus\u2019 De Medicina","volume":"5","author":"Blatchford","year":"2024","journal-title":"Ann Surg Open"},{"key":"10.1016\/j.bjps.2026.03.028_bib22","series-title":"The canon of medicine","author":"Avicenna","year":"1973"},{"key":"10.1016\/j.bjps.2026.03.028_bib23","series-title":"Inventarium sive Chirurgia Magna","year":"1997"},{"key":"10.1016\/j.bjps.2026.03.028_bib24","series-title":"Taiping Shenghui Fang: a collection of overseas-repatriated rare ancient Chinese medical texts","first-page":"2918","author":"Cao","year":"2005"},{"key":"10.1016\/j.bjps.2026.03.028_bib25","series-title":"Complete modern research compilation of prescriptions in the compendium of materia medica (surgical volume)","first-page":"712","author":"Wang","year":"1998"},{"key":"10.1016\/j.bjps.2026.03.028_bib26","unstructured":"Wilcox L. Categorized essentials of repairing the body: Zheng Ti Lei Yao. Chinese medicine database."},{"key":"10.1016\/j.bjps.2026.03.028_bib27","series-title":"Yizong Jinjian: essentials of surgical medicine","first-page":"163","author":"Wu","year":"1973"},{"issue":"7","key":"10.1016\/j.bjps.2026.03.028_bib28","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1111\/jcmm.12060","article-title":"Mechanobiological dysregulation of the epidermis and dermis in skin disorders and in degeneration","volume":"17","author":"Ogawa","year":"2013","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.bjps.2026.03.028_bib29","series-title":"Complete works of ulcer medicine (Yangyi Daquan)","first-page":"414","author":"Gu","year":"1994"},{"key":"10.1016\/j.bjps.2026.03.028_bib30","first-page":"207","article-title":"Note sur la ch\u00e9lo\u00efde","volume":"2","author":"Alibert","year":"1816","journal-title":"J Univers Sci Med"},{"key":"10.1016\/j.bjps.2026.03.028_bib31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1177\/095952875403700106","article-title":"On the keloid of Alibert, and on true keloid","volume":"37","author":"Addison","year":"1854","journal-title":"Med Chir Trans"},{"key":"10.1016\/j.bjps.2026.03.028_bib32","unstructured":"Alibert JLM. Description des maladies de la peau observ\u00e9es \u00e0 l'H\u00f4pital Saint-Louis. Paris; 1825. Available at: \u3008https:\/\/archive.org\u3009. [Accessed January 22, 2026]."},{"key":"10.1016\/j.bjps.2026.03.028_bib33","series-title":"A practical treatise on diseases of the skin","author":"Mark","year":"1851"},{"key":"10.1016\/j.bjps.2026.03.028_bib34","series-title":"Keloid tumor","author":"Maury","year":"2026"},{"key":"10.1016\/j.bjps.2026.03.028_bib35","unstructured":"Mark LP. Keloid over the centre of the sternum. Wikimedia Commons.\u00a0[Accessed January 22, 2026]."},{"key":"10.1016\/j.bjps.2026.03.028_bib36","series-title":"The surgical history of the naval war between Japan and China (1894\u201395)","author":"Saneyoshi","year":"2026"},{"issue":"23_Suppl 1","key":"10.1016\/j.bjps.2026.03.028_bib37","first-page":"III27","article-title":"Role of endothelial dysfunction in atherosclerosis","volume":"109","author":"Davignon","year":"2004","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.bjps.2026.03.028_bib38","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1272\/jnms.JNMS.2021_88-106","article-title":"The latest strategy for keloid and hypertrophic scar prevention and treatment: the Nippon Medical School protocol","volume":"88","author":"Ogawa","year":"2021","journal-title":"J Nippon Med Sch"},{"issue":"2","key":"10.1016\/j.bjps.2026.03.028_bib39","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ejogrb.2009.12.005","article-title":"Fetal programming of atherosclerosis: possible role of the mitochondria","volume":"149","author":"Leduc","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol"}],"container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681526001713?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1748681526001713?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T11:30:08Z","timestamp":1779535808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1748681526001713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":39,"alternative-id":["S1748681526001713"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2026.03.028","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Keloid may be a modern inflammatory disease: A historical and clinicopathological perspective","name":"articletitle","label":"Article Title"},{"value":"Journal of Plastic, Reconstructive & Aesthetic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjps.2026.03.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.","name":"copyright","label":"Copyright"}]}}