{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:16:15Z","timestamp":1789143375131,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jprasurg.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bjps.2026.08.004","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T23:39:18Z","timestamp":1786145958000},"page":"168-179","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Degenerative vascular changes and risk of anastomosis thrombosis in microsurgical breast reconstruction: A clinical and histomorphometric analysis"],"prefix":"10.1016","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1760-6791","authenticated-orcid":false,"given":"Thiago","family":"Ueda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3225-0974","authenticated-orcid":false,"given":"Alexandre Mendon\u00e7a","family":"Munhoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6198-4726","authenticated-orcid":false,"given":"Eduardo","family":"Montag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Yoshikazu","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3602-9019","authenticated-orcid":false,"given":"Fernando Nalesso","family":"Aguiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5470-452X","authenticated-orcid":false,"given":"Esther Mihwa Oh","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Eduardo Marins de","family":"Benedette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio de Freitas","family":"Busnardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Gemperli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.bjps.2026.08.004_bib1","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.21037\/gs-23-288","article-title":"Current status of autologous breast reconstruction in Europe: how to reduce donor site morbidity","volume":"12","author":"Hamdi","year":"2023","journal-title":"Gland Surg"},{"issue":"5","key":"10.1016\/j.bjps.2026.08.004_bib2","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0007-1226(03)00198-X","article-title":"Better cosmetic results and comparable quality of life after skin-sparing mastectomy and immediate autologous breast reconstruction compared to breast conservative treatment","volume":"56","author":"Cocquyt","year":"2003","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.bjps.2026.08.004_bib3","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1097\/01.prs.0000260636.43385.90","article-title":"Changing trends in recipient vessel selection for microvascular autologous breast reconstruction: an analysis of 1483 consecutive cases","volume":"119","author":"Saint-Cyr","year":"2007","journal-title":"Plast Reconstr Surg"},{"issue":"5","key":"10.1016\/j.bjps.2026.08.004_bib4","article-title":"A systematic review and meta-analysis of clinical outcomes in autologous breast reconstruction using internal mammary artery perforators as recipient vessels","volume":"11","author":"Fernandez-Diaz","year":"2023","journal-title":"Plast Reconstr Surg Glob Open"},{"issue":"3","key":"10.1016\/j.bjps.2026.08.004_bib5","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bjps.2003.12.004","article-title":"Algorithm in choosing recipient vessels for perforator free flap in breast reconstruction: the role of the internal mammary perforators","volume":"57","author":"Hamdi","year":"2004","journal-title":"Br J Plast Surg"},{"issue":"3","key":"10.1016\/j.bjps.2026.08.004_bib6","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/micr.22203","article-title":"Internal mammary perforator vessels as recipient site for microsurgical breast reconstruction: a comparative histomorphometric analysis and incidence of degenerative vascular changes","volume":"34","author":"Munhoz","year":"2014","journal-title":"Microsurgery"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib7","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/01.PRS.0000129074.88594.D7","article-title":"Perforator flap breast reconstruction using internal mammary perforator branches as a recipient site: an anatomical and clinical analysis","volume":"114","author":"Munhoz","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.bjps.2026.08.004_bib8","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1097\/PRS.0b013e318218fc95","article-title":"Closer to an understanding of fate: the role of vascular complications in free flap breast reconstruction","volume":"128","author":"Fosnot","year":"2011","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.bjps.2026.08.004_bib9","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1097\/01.prs.0000236898.87398.d6","article-title":"Complications after microvascular breast reconstruction: experience with 1195 flaps","volume":"118","author":"Mehrara","year":"2006","journal-title":"Plast Reconstr Surg"},{"issue":"7","key":"10.1016\/j.bjps.2026.08.004_bib10","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1002\/jso.25714","article-title":"Development and validation of a risk stratification model for immediate microvascular breast reconstruction","volume":"120","author":"Roy","year":"2019","journal-title":"J Surg Oncol"},{"issue":"8","key":"10.1016\/j.bjps.2026.08.004_bib11","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/micr.22250","article-title":"Predictive risk factors of free flap thrombosis in breast reconstruction surgery","volume":"34","author":"Masoomi","year":"2014","journal-title":"Microsurgery"},{"issue":"10","key":"10.1016\/j.bjps.2026.08.004_bib12","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/j.bjps.2016.07.006","article-title":"Predictors and consequences of intraoperative microvascular problems in autologous breast reconstruction","volume":"69","author":"O\u2019Neill","year":"2016","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib13","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1010-5182(96)80073-4","article-title":"Histological changes in vessels used for microvascular reconstruction in the head and neck","volume":"24","author":"Shibahara","year":"1996","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2007-1006956","article-title":"Preoperative assessment of the peripheral vascular disease patient for free tissue transfers","volume":"4","author":"Colen","year":"1987","journal-title":"J Reconstr Microsurg"},{"issue":"3","key":"10.1016\/j.bjps.2026.08.004_bib15","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.radonc.2009.05.021","article-title":"Novel insights into pathological changes in muscular arteries of radiotherapy patients","volume":"92","author":"Russell","year":"2009","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.bjps.2026.08.004_bib16","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3109\/00365526909180620","article-title":"Gastric arteriosclerosis in elderly people","volume":"4","author":"Larsen","year":"1969","journal-title":"Scand J Gastroenterol"},{"issue":"6","key":"10.1016\/j.bjps.2026.08.004_bib17","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/0003-4975(89)90027-1","article-title":"Incidence of atherosclerosis in the internal mammary artery","volume":"47","author":"Sisto","year":"1989","journal-title":"Ann Thoracic Surg"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211421","article-title":"Histomorphometric analysis of the human internal thoracic artery and relationship with cardiovascular risk factors","volume":"14","author":"Fonseca","year":"2019","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bjps.2026.08.004_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130374","article-title":"Micro-CT technique is well suited for documentation of remodeling processes in murine carotid arteries","volume":"10","author":"Sch\u00dcrmann","year":"2015","journal-title":"PLoS One"},{"issue":"23","key":"10.1016\/j.bjps.2026.08.004_bib20","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2009.09.009","article-title":"Transatlantic network on atherothrombosis. Inflammation in atherosclerosis: from pathophysiology to practice","volume":"54","author":"Libby","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.bjps.2026.08.004_bib21","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1161\/ATVBAHA.112.249680","article-title":"Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors","volume":"32","author":"Iwamoto","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.bjps.2026.08.004_bib22","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1161\/01.STR.27.2.224","article-title":"Thickening of the carotid wall. A marker for atherosclerosis in the elderly? Cardiovascular health study collaborative research group","volume":"27","author":"O'Leary","year":"1996","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib23","first-page":"21","article-title":"Pathogenesis of atherosclerosis in the tunica intima, media, and adventitia of coronary arteries: an updated review","volume":"20","author":"Milutinovi\u0107","year":"2020","journal-title":"Bosn J Basic Med Sci."},{"issue":"5","key":"10.1016\/j.bjps.2026.08.004_bib24","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1161\/ATVBAHA.106.134080","article-title":"Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration","volume":"27","author":"Nakashima","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.bjps.2026.08.004_bib25","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/j.jtcvs.2016.02.018","article-title":"Histomorphologic superiority of internal thoracic arteries over right gastroepiploic arteries for coronary bypass","volume":"151","author":"Nakajima","year":"2016","journal-title":"J Thor Cardiovasc Surg"},{"issue":"2","key":"10.1016\/j.bjps.2026.08.004_bib26","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1161\/CIRCRESAHA.116.301312","article-title":"Inflammatory and immune responses in the arterial media","volume":"116","author":"Tellides","year":"2015","journal-title":"Circ Res"},{"issue":"3","key":"10.1016\/j.bjps.2026.08.004_bib27","doi-asserted-by":"crossref","first-page":"584","DOI":"10.5603\/FM.a2021.0084","article-title":"Morphologic comparison of blood vessels used for coronary artery bypass graft surgery","volume":"81","author":"Garnizone","year":"2022","journal-title":"Folia Morphol"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib28","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1161\/01.RES.20.1.99","article-title":"A lamellar unit of aortic medial structure and function in mammals","volume":"20","author":"Wolinsky","year":"1967","journal-title":"Circ Res"},{"key":"10.1016\/j.bjps.2026.08.004_bib29","series-title":"Cardiovascular therapeutics: a companion to Braunwald\u2019s heart disease","first-page":"214","author":"Baron","year":"2013"},{"issue":"8.","key":"10.1016\/j.bjps.2026.08.004_bib30","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jacc.2005.09.068","article-title":"Pathogenesis of atherosclerosis","volume":"47","author":"Falk","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.bjps.2026.08.004_bib31","doi-asserted-by":"crossref","first-page":"840e","DOI":"10.1097\/PRS.0000000000004990","article-title":"Assessing age as a risk factor for complications in autologous breast reconstruction","volume":"142","author":"Torabi","year":"2018","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.bjps.2026.08.004_bib32","first-page":"519","article-title":"Why is the mammary artery so special and what protects it from atherosclerosis?","volume":"2","author":"Otsuka","year":"2013","journal-title":"Ann Cardiothoracic Surg"},{"issue":"12","key":"10.1016\/j.bjps.2026.08.004_bib33","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s11883-016-0632-z","article-title":"The different facets of dyslipidemia and hypertension in atherosclerosis","volume":"18","author":"Hurtubise","year":"2016","journal-title":"Curr Atheroscler Rep"},{"issue":"7","key":"10.1016\/j.bjps.2026.08.004_bib34","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1161\/ATVBAHA.112.300154","article-title":"Mechanisms of coronary thrombosis in cigarette smoke exposure","volume":"33","author":"Barua","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"7","key":"10.1016\/j.bjps.2026.08.004_bib35","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1055\/s-0038-1639377","article-title":"Does cigarette smoking harm microsurgical free flap reconstruction?","volume":"34","author":"Ehrl","year":"2018","journal-title":"J Reconstr Microsurg"},{"issue":"5","key":"10.1016\/j.bjps.2026.08.004_bib36","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1245\/s10434-014-3494-z","article-title":"A systematic review of morbidity associated with autologous breast reconstruction before and after exposure to radiotherapy: are current practices ideal?","volume":"21","author":"Kelley","year":"2014","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.bjps.2026.08.004_bib37","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1055\/s-0037-1602741","article-title":"The impact of radiation and its timing on donor internal mammary vessel histopathology at the time of autologous microvascular breast reconstruction","volume":"33","author":"Odom","year":"2017","journal-title":"J Reconstr Microsurg"},{"issue":"2","key":"10.1016\/j.bjps.2026.08.004_bib38","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10549-019-05241-9","article-title":"The influence of neoadjuvant chemotherapy on complications of immediate DIEP flap breast reconstructions","volume":"176","author":"Beugels","year":"2019","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.bjps.2026.08.004_bib39","article-title":"Impact of neoadjuvant chemotherapy on immediate breast reconstruction: a meta-analysis","volume":"98225","author":"Song","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bjps.2026.08.004_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PRS.0000000000005695","article-title":"Synergistic interaction increases complication rates following microvascular breast reconstruction","volume":"144","author":"Roy","year":"2019","journal-title":"Plast Reconstr Surg"}],"container-title":["Journal of Plastic, Reconstructive &amp; Aesthetic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174868152600450X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174868152600450X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:01:43Z","timestamp":1789142503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S174868152600450X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":40,"alternative-id":["S174868152600450X"],"URL":"https:\/\/doi.org\/10.1016\/j.bjps.2026.08.004","relation":{},"ISSN":["1748-6815"],"issn-type":[{"value":"1748-6815","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Degenerative vascular changes and risk of anastomosis thrombosis in microsurgical breast reconstruction: A clinical and histomorphometric analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Plastic, Reconstructive & Aesthetic Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjps.2026.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}