{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:02:45Z","timestamp":1793318565847,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008460","name":"National Center for Complementary and Integrative Health","doi-asserted-by":"publisher","award":["K23AT009374"],"award-info":[{"award-number":["K23AT009374"]}],"id":[{"id":"10.13039\/100008460","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/23705-3"],"award-info":[{"award-number":["2018\/23705-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brazilian Journal of Physical Therapy"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.bjpt.2021.07.003","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T01:45:47Z","timestamp":1631151947000},"page":"688-697","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":61,"title":["Therapeutic ultrasound for knee osteoarthritis: A systematic review and meta-analysis with grade quality assessment"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6188-7552","authenticated-orcid":false,"given":"Lucas Ogura","family":"Dantas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikala C.","family":"Osani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raveendhara R.","family":"Bannuru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9859","key":"10.1016\/j.bjpt.2021.07.003_bib0001","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/S0140-6736(12)61729-2","article-title":"Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990\u20132010: a systematic analysis for the global burden of disease study 2010","volume":"380","author":"Vos","year":"2012","journal-title":"Lancet"},{"issue":"10182","key":"10.1016\/j.bjpt.2021.07.003_bib0002","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/S0140-6736(19)30417-9","article-title":"Osteoarthritis","volume":"393","author":"Hunter","year":"2019","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.bjpt.2021.07.003_bib0003","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.joca.2017.12.003","article-title":"Too much opioid, too much harm","volume":"26","author":"Deveza","year":"2018","journal-title":"Osteoarthr Cartil"},{"issue":"6","key":"10.1016\/j.bjpt.2021.07.003_bib0004","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.joca.2019.01.005","article-title":"Opioid use in knee or hip osteoarthritis: a region-wide population-based cohort study","volume":"27","author":"Thorlund","year":"2019","journal-title":"Osteoarthr Cartil"},{"issue":"11","key":"10.1016\/j.bjpt.2021.07.003_bib0005","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.joca.2019.06.011","article-title":"OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis","volume":"27","author":"Bannuru","year":"2019","journal-title":"Osteoarthr Cartil"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0006","doi-asserted-by":"crossref","DOI":"10.1097\/RHU.0000000000000562","article-title":"Barriers impeding the use of non-pharmacological, non-surgical care in hip and knee osteoarthritis: the views of general practitioners, physical therapists, and medical specialists","author":"Selten","year":"2017","journal-title":"J Clin Rheumatol"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0007","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ultras.2008.02.004","article-title":"Ultrasound in contemporary physiotherapy practice","volume":"48","author":"Watson","year":"2008","journal-title":"Ultrasonics"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0008","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.mcna.2014.03.009","article-title":"The physical therapy prescription","volume":"98","author":"Onks","year":"2014","journal-title":"Med Clin North Am"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0009","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ultras.2008.02.002","article-title":"Therapeutic opportunities in biological responses of ultrasound","volume":"48","author":"Paliwal","year":"2008","journal-title":"Ultrasonics"},{"issue":"7","key":"10.1016\/j.bjpt.2021.07.003_bib0010","doi-asserted-by":"crossref","first-page":"p1351","DOI":"10.1093\/ptj\/81.7.1351","article-title":"A review of therapeutic ultrasound: biophysical effects. 2001","volume":"81","author":"Baker","year":"2001","journal-title":"Phys Ther"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0011","article-title":"Therapeutic ultrasound for osteoarthritis of the knee or hip","author":"Rutjes","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"10.1016\/j.bjpt.2021.07.003_bib0012","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.joca.2010.06.010","article-title":"Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis","volume":"18","author":"Loyola-S\u00e1nchez","year":"2010","journal-title":"Osteoarthr Cartil"},{"issue":"8","key":"10.1016\/j.bjpt.2021.07.003_bib0013","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.joca.2014.06.028","article-title":"Effectiveness of continuous and pulsed ultrasound for the management of knee osteoarthritis: a systematic review and network meta-analysis","volume":"22","author":"Zeng","year":"2014","journal-title":"Osteoarthr Cartil"},{"issue":"10","key":"10.1016\/j.bjpt.2021.07.003_bib0014","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1177\/0269215515609415","article-title":"Effects of therapeutic ultrasound on pain, physical functions and safety outcomes in patients with knee osteoarthritis: a systematic review and meta-analysis","volume":"30","author":"Zhang","year":"2016","journal-title":"Clin Rehabil"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0015","first-page":"1","article-title":"Effects of low-intensity pulsed ultrasound on knee osteoarthritis: a meta-analysis of randomized clinical trials","volume":"2018","author":"Zhou","year":"2018","journal-title":"Biomed Res Int"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0017","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jclinepi.2010.09.012","article-title":"GRADE guidelines: 2. Framing the question and deciding on important outcomes","volume":"64","author":"Guyatt","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0018","doi-asserted-by":"crossref","DOI":"10.2519\/jospt.2011.3333","article-title":"A guide to understanding meta-analysis","author":"Israel","year":"2011","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0019","unstructured":"The Cochrane collaboration. The Cochrane Risk of Bias Tool. http:\/\/handbook.cochrane.org."},{"key":"10.1016\/j.bjpt.2021.07.003_bib0020","unstructured":"The Cochrane collaboration. RevMan 5.3. - http:\/\/tech.cochrane.org\/revman."},{"key":"10.1016\/j.bjpt.2021.07.003_bib0021","series-title":"GRADEpro Guideline Development Tool [Software]","year":"2015"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0022","series-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"1998"},{"issue":"7129","key":"10.1016\/j.bjpt.2021.07.003_bib0023","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.316.7129.469","article-title":"Bias in meta-analysis detected by a simple, graphical","volume":"316","author":"Stuck","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0024","series-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins","year":"2011"},{"issue":"3","key":"10.1016\/j.bjpt.2021.07.003_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"issue":"11","key":"10.1016\/j.bjpt.2021.07.003_bib0026","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1517\/14656560903018911","article-title":"The treatment and prevention of knee osteoarthritis: a tool for clinical decision-making","volume":"10","author":"Bliddal","year":"2009","journal-title":"Expert Opin Pharmacother"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0027","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"10.1016\/j.bjpt.2021.07.003_bib0028","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0029","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1471-2288-8-79","article-title":"Undue reliance on I(2) in assessing heterogeneity may mislead","volume":"8","author":"R\u00fccker","year":"2008","journal-title":"BMC Med Res Methodol"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0030","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ultrasmedbio.2016.08.035","article-title":"The effect of therapeutic ultrasound on pain and physical function in patients with knee osteoarthritis","volume":"43","author":"Ye\u011fin","year":"2017","journal-title":"Ultrasound Med Biol"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0031","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.apmr.2011.07.196","article-title":"Effect of low-intensity pulsed ultrasound on the cartilage repair in people with mild to moderate knee osteoarthritis: a double-blinded, randomized, placebo-controlled pilot study","volume":"93","author":"Loyola-S\u00e1nchez","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0032","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1177\/147323001003800404","article-title":"Short-term effectiveness of ultrasound therapy in knee osteoarthritis","volume":"38","author":"Tascioglu","year":"2010","journal-title":"J Int Med Res"},{"issue":"3","key":"10.1016\/j.bjpt.2021.07.003_bib0033","first-page":"144","article-title":"Short-term efficacy of pulsed electromagnetic field therapy on pain and functional level in knee osteoarthritis: a randomized controlled study","volume":"24","author":"K\u00fclc\u00fc","year":"2009","journal-title":"Turk J Rheumatol"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0034","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ultrasmedbio.2008.07.009","article-title":"A double-blind trial of clinical effects of therapeutic ultrasound in knee osteoarthritis","volume":"35","author":"\u00d6zg\u00f6nenel","year":"2009","journal-title":"Ultrasound Med Biol"},{"issue":"2","key":"10.1016\/j.bjpt.2021.07.003_bib0035","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.joca.2017.11.015","article-title":"The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials","volume":"26","author":"Wang","year":"2018","journal-title":"Osteoarthr Cartil"},{"issue":"5","key":"10.1016\/j.bjpt.2021.07.003_bib0036","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/s11914-015-0280-1","article-title":"The role of peripheral nociceptive neurons in the pathophysiology of osteoarthritis pain","volume":"13","author":"Miller","year":"2015","journal-title":"Curr Osteoporos Rep"},{"issue":"12","key":"10.1016\/j.bjpt.2021.07.003_bib0037","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.pmrj.2017.05.008","article-title":"The role of low-intensity pulsed ultrasound on cartilage healing in knee osteoarthritis: a review","volume":"9","author":"Rothenberg","year":"2017","journal-title":"PM&R"},{"issue":"2","key":"10.1016\/j.bjpt.2021.07.003_bib0038","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/rmdopen-2018-000715","article-title":"Patient-reported outcome measures in osteoarthritis: a systematic search and review of their use and psychometric properties","volume":"4","author":"Lundgren-Nilsson","year":"2018","journal-title":"RMD Open"},{"issue":"2","key":"10.1016\/j.bjpt.2021.07.003_bib0039","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/PHM.0000000000000357","article-title":"Performance-based versus self-reported outcomes using the hip disability and osteoarthritis outcome score after total hip arthroplasty","volume":"95","author":"Dayton","year":"2016","journal-title":"Am J Phys Med Rehabil"},{"issue":"7","key":"10.1016\/j.bjpt.2021.07.003_bib0040","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.jclinepi.2005.11.019","article-title":"Self-reported physical functioning was more influenced by pain than performance-based physical functioning in knee-osteoarthritis patients","volume":"59","author":"Terwee","year":"2006","journal-title":"J Clin Epidemiol"},{"issue":"5","key":"10.1016\/j.bjpt.2021.07.003_bib0041","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/PHM.0000000000000033","article-title":"Efficacy of therapeutic ultrasound for the management of knee osteoarthritis: a randomized, controlled, and double-blind study","volume":"93","author":"Cakir","year":"2014","journal-title":"Am J Phys Med Rehabil"},{"issue":"September","key":"10.1016\/j.bjpt.2021.07.003_bib0042","first-page":"1","article-title":"Efficacy of focused low-intensity pulsed ultrasound therapy for the management of knee osteoarthritis: a randomized, double blind, placebo-controlled trial","volume":"6","author":"Jia","year":"2016","journal-title":"Sci Rep"},{"issue":"4","key":"10.1016\/j.bjpt.2021.07.003_bib0043","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/acr.21596","article-title":"American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee","volume":"64","author":"Hochberg","year":"2012","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0044","article-title":"National institute for health and care excellence. osteoarthritis: care and management","author":"Chae","year":"2014","journal-title":"Natl Clin Guidel Cent (UK)"},{"issue":"5","key":"10.1016\/j.bjpt.2021.07.003_bib0045","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1177\/0269215517691083","article-title":"The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part one: introduction, and mind-body exercise programs","volume":"31","author":"Brosseau","year":"2017","journal-title":"Clin Rehabil"},{"issue":"5","key":"10.1016\/j.bjpt.2021.07.003_bib0046","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1177\/0269215517691084","article-title":"The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part two: strengthening exercise programs","volume":"31","author":"Brosseau","year":"2017","journal-title":"Clin Rehabil"},{"issue":"5","key":"10.1016\/j.bjpt.2021.07.003_bib0047","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1177\/0269215517691083","article-title":"The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part three: aerobic exercise programs","volume":"31","author":"Brosseau","year":"2017","journal-title":"Clin Rehabil"},{"issue":"7","key":"10.1016\/j.bjpt.2021.07.003_bib0048","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1136\/annrheumdis-2012-202745","article-title":"EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis","volume":"72","author":"Fernandes","year":"2013","journal-title":"Ann Rheum Dis"},{"issue":"7766","key":"10.1016\/j.bjpt.2021.07.003_bib0049","first-page":"241","article-title":"Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study","volume":"341","author":"N\u00fcesch","year":"2010","journal-title":"BMJ"},{"key":"10.1016\/j.bjpt.2021.07.003_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/348014","article-title":"Physical therapists in primary care are interested in high quality evidence regarding efficacy of therapeutic ultrasound for knee osteoarthritis: a provincial survey","volume":"2013","author":"MacIntyre","year":"2013","journal-title":"Sci World J"},{"issue":"1","key":"10.1016\/j.bjpt.2021.07.003_bib0051","doi-asserted-by":"crossref","first-page":"40","DOI":"10.7326\/M17-0046","article-title":"CONSORT statement for randomized trials of nonpharmacologic treatments: a 2017 update and a CONSORT extension for nonpharmacologic trial abstracts","volume":"167","author":"Barbour","year":"2017","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.bjpt.2021.07.003_bib0052","doi-asserted-by":"crossref","DOI":"10.2519\/jospt.2016.0108","article-title":"The TIDieR checklist will beneit the physical therapy profession","volume":"46","author":"Yamato","year":"2016","journal-title":"J Orthop Sport Phys Ther"}],"container-title":["Brazilian Journal of Physical Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1413355521000812?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1413355521000812?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:53:43Z","timestamp":1761407623000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1413355521000812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1413355521000812"],"URL":"https:\/\/doi.org\/10.1016\/j.bjpt.2021.07.003","relation":{},"ISSN":["1413-3555"],"issn-type":[{"value":"1413-3555","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic ultrasound for knee osteoarthritis: A systematic review and meta-analysis with grade quality assessment","name":"articletitle","label":"Article Title"},{"value":"Brazilian Journal of Physical Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bjpt.2021.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Associa\u00e7\u00e3o Brasileira de Pesquisa e P\u00f3s-Gradua\u00e7\u00e3o em Fisioterapia. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}