{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:09:46Z","timestamp":1793369386219,"version":"4.5.0"},"reference-count":90,"publisher":"Elsevier BV","issue":"1","content-domain":{"domain":["bloodreviews.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Reviews"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.blre.2013.12.002","type":"journal-article","created":{"date-parts":[[2014,1,11]],"date-time":"2014-01-11T10:02:55Z","timestamp":1389434575000},"page":"23-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":111,"title":["Bone marrow necrosis and fat embolism syndrome in sickle cell disease: Increased susceptibility of patients with non-SS genotypes and a possible association with human parvovirus B19 infection"],"prefix":"10.1016","volume":"28","author":[{"given":"Dimitris A.","family":"Tsitsikas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Gallinella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sneha","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Seligman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Greaves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger J.","family":"Amos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.blre.2013.12.002_bb0005","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1046\/j.1365-2044.2001.01724.x","article-title":"Fat embolism","volume":"56","author":"Mellor","year":"2001","journal-title":"Anaesthesia"},{"key":"10.1016\/j.blre.2013.12.002_bb0010","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/MAJ.0b013e318172f5d2","article-title":"Fat embolism syndrome","volume":"336","author":"Stein","year":"2008","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.blre.2013.12.002_bb0015","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/ajh.10114","article-title":"Bone marrow necrosis: clinicopathologic analysis of 20 cases and review of the literature","volume":"70","author":"Paydas","year":"2002","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0020","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1002\/(SICI)1097-0142(20000415)88:8<1769::AID-CNCR3>3.0.CO;2-H","article-title":"Bone marrow necrosis","volume":"88","author":"Janssens","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.blre.2013.12.002_bb0025","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1001\/archinte.1978.03630350089025","article-title":"Bone marrow necrosis. Acute microcirculation failure in myelomonocytic leukemia","volume":"138","author":"Bernard","year":"1978","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0030","first-page":"47","article-title":"Necrosis of the bone marrow with fat embolism in sickle cell anemia","volume":"17","author":"Wade","year":"1941","journal-title":"Am J Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0035","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/ajh.20348","article-title":"Bone marrow embolism in sickle cell disease: a review","volume":"79","author":"Dang","year":"2005","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0040","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/PAF.0b013e3181873c90","article-title":"Sickle cell disease: two fatalities due to bone marrow emboli in patients with acute chest syndrome","volume":"30","author":"Hawley","year":"2009","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0045","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/S0889-8588(05)70401-9","article-title":"Systemic fat embolism and pulmonary hypertension in sickle cell disease","volume":"10","author":"Castro","year":"1996","journal-title":"Hematol Oncol Clin North Am"},{"key":"10.1016\/j.blre.2013.12.002_bb0050","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/ajh.2830430431","article-title":"Pulmonary fat embolism after prostaglandin infusion in sickle cell disease with fatal outcome despite exchange blood transfusion","volume":"43","author":"Godeau","year":"1993","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0055","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1001\/archinte.1984.00350130211039","article-title":"Fat embolism in sickle cell disease. Report of a case with brief review of the literature","volume":"144","author":"Shapiro","year":"1984","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0060","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0002-9343(75)90132-1","article-title":"Hemoglobin S\/C disease in a pregnant woman with crisis and fat embolization syndrome","volume":"58","author":"Chmel","year":"1975","journal-title":"Am J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0065","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/0002-9378(59)90373-4","article-title":"Pregnancy in sickle cell, anemia, sickle cell-hemoglobin C disease, and variants thereof","volume":"77","author":"Curtis","year":"1959","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.blre.2013.12.002_bb0070","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1182\/blood.V60.6.1411.1411","article-title":"Bone marrow infarction in sickle cell anemia: correlation with hematologic profiles","volume":"60","author":"Milner","year":"1982","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0075","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/ajcp\/84.2.209","article-title":"Is pain crisis a cause of death in sickle cell disease?","volume":"84","author":"Parfrey","year":"1985","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0080","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1365-2141.2003.04594.x","article-title":"Causes of death in sickle cell disease: an autopsy study","volume":"123","author":"Manci","year":"2003","journal-title":"Br J Haematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0085","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/ajh.20685","article-title":"Circumstances of death in adult sickle cell disease patients","volume":"81","author":"Darbari","year":"2006","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0090","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1056\/NEJM199406093302303","article-title":"Mortality in sickle cell disease. Life expectancy and risk factors for early death","volume":"330","author":"Platt","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0095","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/01.paf.0000257397.92466.50","article-title":"Sickle cell lung disease and sudden death: a retrospective\/prospective study of 21 autopsy cases and literature review","volume":"28","author":"Graham","year":"2007","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0100","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0002-9343(94)90136-8","article-title":"Acute multiorgan failure syndrome: a potentially catastrophic complication of severe sickle cell pain episodes","volume":"96","author":"Hassell","year":"1994","journal-title":"Am J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0105","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1097\/01.SMJ.0000140829.91526.CD","article-title":"Multi-organ failure associated with acute parvovirus infection and exercise in a patient with sickle beta thalassemia","volume":"97","author":"Nguyen","year":"2004","journal-title":"South Med J"},{"key":"10.1016\/j.blre.2013.12.002_bb0110","doi-asserted-by":"crossref","first-page":"E6","DOI":"10.1016\/S0272-6386(03)00666-8","article-title":"Multiorgan failure during a sickle cell crisis in sickle\/beta-thalassemia","volume":"42","author":"Tedla","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.blre.2013.12.002_bb0115","doi-asserted-by":"crossref","first-page":"3998","DOI":"10.1182\/blood.V97.12.3998","article-title":"Granulocyte colony-stimulating factor-induced sickle cell crisis and multiorgan dysfunction in a patient with compound heterozygous sickle cell\/beta+ thalassemia","volume":"97","author":"Grigg","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0120","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/ajh.23117","article-title":"Multiorgan failure and bone marrow necrosis in three adults with sickle cell-\u03b2+-thalassemia","volume":"87","author":"Adamski","year":"2012","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0125","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1182\/blood.V67.5.1411.1411","article-title":"Human parvovirus B19-induced epidemic acute red cell aplasia in patients with hereditary hemolytic anemia","volume":"67","author":"Saarinen","year":"1986","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0130","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/S0140-6736(01)06807-6","article-title":"Haematological response to parvovirus B19 infection in homozygous sickle-cell disease","volume":"358","author":"Serjeant","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.blre.2013.12.002_bb0135","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.crad.2012.03.001","article-title":"Cerebral fat embolism syndrome in sickle cell anaemia\/\u03b2-thalassemia: importance of susceptibility-weighted MRI","volume":"67","author":"Mossa-Basha","year":"2012","journal-title":"Clin Radiol"},{"key":"10.1016\/j.blre.2013.12.002_bb0140","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1182\/blood-2003-01-0069","article-title":"Epidemiology of human parvovirus B19 in children with sickle cell disease","volume":"103","author":"Smith-Whitley","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0145","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/ajh.22177","article-title":"Keeping it in the family: three relatives with HbSC disease and simultaneous acute pulmonary emboli","volume":"87","author":"Hawkins","year":"2012","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0150","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1182\/blood.V83.11.3107.3107","article-title":"Pulmonary fat embolism: a distinct cause of severe acute chest syndrome in sickle cell anemia","volume":"83","author":"Vichinsky","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0155","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1056\/NEJM200006223422502","article-title":"Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group","volume":"342","author":"Vichinsky","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0160","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1182\/blood.V84.2.643.643","article-title":"The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell Disease","volume":"84","author":"Castro","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0165","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJM199107043250103","article-title":"Pain in sickle cell disease. Rates and risk factors","volume":"325","author":"Platt","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0170","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1111\/j.1537-2995.2006.00960.x","article-title":"Transfusion medicine illustrated. Marrow emboli in acute chest syndrome: artifact or etiology?","volume":"46","author":"McCarthy","year":"2006","journal-title":"Transfusion (Paris)"},{"key":"10.1016\/j.blre.2013.12.002_bb0175","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1046\/j.1365-2796.1999.0445f.x","article-title":"Sickle cell-like crisis and bone marrow necrosis associated with parvovirus B19 infection and heterozygosity for haemoglobins S and E","volume":"245","author":"Eichhorn","year":"1999","journal-title":"J Intern Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0180","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/(SICI)1096-8652(199603)51:3<207::AID-AJH5>3.0.CO;2-0","article-title":"Sickle cell acute chest syndrome associated with parvovirus B19 infection: case series and review","volume":"51","author":"Lowenthal","year":"1996","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0185","doi-asserted-by":"crossref","first-page":"731","DOI":"10.2217\/fvl.10.56","article-title":"Parvovirus infection-induced cell death and cell cycle arrest","volume":"5","author":"Chen","year":"2010","journal-title":"Futur Virol"},{"key":"10.1016\/j.blre.2013.12.002_bb0190","doi-asserted-by":"crossref","first-page":"7942","DOI":"10.1128\/JVI.00891-08","article-title":"Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3\/PIAS3 in human endothelial cells","volume":"82","author":"Duechting","year":"2008","journal-title":"J Virol"},{"key":"10.1016\/j.blre.2013.12.002_bb0195","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1086\/499599","article-title":"Activation of synoviocytes by the secreted phospholipase A2 motif in the VP1-unique region of parvovirus B19 minor capsid protein","volume":"193","author":"Lu","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.blre.2013.12.002_bb0200","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.autrev.2008.07.005","article-title":"Human parvovirus B19 infection and autoimmunity","volume":"8","author":"Lunardi","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.blre.2013.12.002_bb0205","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1086\/513280","article-title":"Comparison of tissue distribution, persistence, and molecular epidemiology of parvovirus B19 and novel human parvoviruses PARV4 and human bocavirus","volume":"195","author":"Manning","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.blre.2013.12.002_bb0210","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1053\/hupa.2003.48","article-title":"Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease","volume":"34","author":"B\u00fcltmann","year":"2003","journal-title":"Hum Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0215","first-page":"1227","article-title":"Parvoviral infection of endothelial cells and its possible role in vasculitis and autoimmune diseases","volume":"29","author":"Magro","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.blre.2013.12.002_bb0220","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jcv.2008.10.008","article-title":"Placental endothelial cells can be productively infected by parvovirus B19","volume":"44","author":"Pasquinelli","year":"2009","journal-title":"J Clin Virol"},{"key":"10.1016\/j.blre.2013.12.002_bb0225","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1182\/blood.V87.6.2573.bloodjournal8762573","article-title":"Phospholipase A2 levels in acute chest syndrome of sickle cell disease","volume":"87","author":"Styles","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.blre.2013.12.002_bb0230","volume":"42","author":"Vance","year":"1941","journal-title":"Sickle cell disease"},{"key":"10.1016\/j.blre.2013.12.002_bb0235","first-page":"752","article-title":"The brain in sickle cell anemia","volume":"47","author":"Wertham","year":"1942"},{"key":"10.1016\/j.blre.2013.12.002_bb0240","first-page":"233","article-title":"Massive fat embolism following marrow infarction in sickle cell anemia","volume":"53","author":"Wyatt","year":"1952","journal-title":"AMA Arch Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0245","first-page":"8","article-title":"Bone marrow and fat embolism in sickle cell anemia and sickle cell-hemoglobin C disease","volume":"103","author":"Shelley","year":"1958","journal-title":"Bull Johns Hopkins Hosp"},{"key":"10.1016\/j.blre.2013.12.002_bb0250","first-page":"212","article-title":"Editorial note","volume":"13","author":"Eastman","year":"1958","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.blre.2013.12.002_bb0255","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/0002-9343(59)90048-8","article-title":"Hemoglobin S-C disease with fat embolism: report of a patient dying in crisis: autopsy findings","volume":"27","author":"Ober","year":"1959","journal-title":"Am J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0260","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1097\/00007611-196112000-00013","article-title":"Fat embolization associated with sickle cell crisis","volume":"54","author":"Graber","year":"1961","journal-title":"South Med J"},{"key":"10.1016\/j.blre.2013.12.002_bb0265","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S0002-9378(16)35295-4","article-title":"Hemoglobin C and S disease in pregnancy. Report of a case with bone marrow and fat emboli","volume":"86","author":"Rywlin","year":"1963","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.blre.2013.12.002_bb0270","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.7326\/0003-4819-67-6-1195","article-title":"Infarction of bone marrow in the sickle cell disorders","volume":"67","author":"Charache","year":"1967","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0275","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1136\/jcp.26.8.620","article-title":"Fat embolism in sickle cell disease","volume":"26","author":"Hutchinson","year":"1973","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0280","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/0002-9394(73)91151-3","article-title":"Anterior segment necrosis following scleral buckling in hemoglobin SC disease","volume":"75","author":"Eagle","year":"1973","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.blre.2013.12.002_bb0285","first-page":"1094","article-title":"Drepanocytic anaemia, bone marrow infarction and probable fat embolism. Report of a case (author's transl)","volume":"25","author":"Carnot","year":"1980","journal-title":"Sangre (Barc)"},{"key":"10.1016\/j.blre.2013.12.002_bb0290","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00000433-199003000-00013","article-title":"Massive fat and necrotic bone marrow embolization in a previously undiagnosed patient with sickle cell disease","volume":"11","author":"Garza","year":"1990","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0295","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0140-6736(94)92300-0","article-title":"Sickling crisis, fat embolism, and coma after steroids","volume":"344","author":"Huang","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.blre.2013.12.002_bb0300","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/ajh.2830460418","article-title":"Fat embolism syndrome associated with asthma and sickle cell-beta(+)-thalassemia","volume":"46","author":"Johnson","year":"1994","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0305","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3109\/08880019509029549","article-title":"Fatal fat embolism in a patient with sickle-beta+ thalassemia","volume":"12","author":"Desselle","year":"1995","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.blre.2013.12.002_bb0310","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0887-8994(94)00108-E","article-title":"Nontraumatic fat embolism syndrome in sickle cell anemia","volume":"12","author":"Horton","year":"1995","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.blre.2013.12.002_bb0315","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0022-3476(95)70353-5","article-title":"Life-threatening infection in two children with hemoglobin S-beta-thalassemia","volume":"126","author":"Lynch","year":"1995","journal-title":"J Pediatr"},{"key":"10.1016\/j.blre.2013.12.002_bb0320","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/0046-8177(95)90304-6","article-title":"Retrospective diagnosis of sickle cell-hemoglobin C disease and parvovirus infection by molecular DNA analysis of postmortem tissue","volume":"26","author":"Goldstein","year":"1995","journal-title":"Hum Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0325","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3109\/15513819609168662","article-title":"Fatal fat embolism syndrome in a child with undiagnosed hemoglobin S\/beta+ thalassemia: a complication of acute parvovirus B19 infection","volume":"16","author":"Kolquist","year":"1996","journal-title":"Pediatr Pathol Lab Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0330","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1136\/jcp.49.9.774","article-title":"Fatal bone marrow embolism in a patient with sickle cell beta+ thalassaemia","volume":"49","author":"Zaidi","year":"1996","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0335","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1056\/NEJM199710303371808","article-title":"Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 34-1997. A 22-year-old man with a sickle cell crisis and sudden death","volume":"337","author":"McMahon","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0340","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/(SICI)1097-0339(199707)17:1<54::AID-DC11>3.0.CO;2-9","article-title":"Cytologic diagnosis of fat emboli in peripheral blood during sickle cell infarctive crisis","volume":"17","author":"Van Hoeven","year":"1997","journal-title":"Diagn Cytopathol"},{"key":"10.1016\/j.blre.2013.12.002_bb0345","first-page":"144","article-title":"Postmortem diagnosis of hemoglobin SC disease complicated by fat embolism","volume":"28","author":"Ballas","year":"1998","journal-title":"Ann Clin Lab Sci"},{"key":"10.1016\/j.blre.2013.12.002_bb0350","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00007611-199902000-00018","article-title":"Pulmonary bone marrow embolism in sickle cell disease","volume":"92","author":"Eckardt","year":"1999","journal-title":"South Med J"},{"key":"10.1016\/j.blre.2013.12.002_bb0355","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1097\/00000441-200011000-00009","article-title":"Bone marrow necrosis in sickle cell disease: a description of three cases and a review of the literature","volume":"320","author":"Ataga","year":"2000","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.blre.2013.12.002_bb0360","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0750-7658(01)00363-X","article-title":"Febrile coma and multiple organ failure: suspected hemoglobinopathy SC","volume":"20","author":"Ouedraogo","year":"2001","journal-title":"Ann Fr Anesth Reanim"},{"key":"10.1016\/j.blre.2013.12.002_bb0365","first-page":"164","article-title":"Cerebral fat embolism and drepanocytosis","volume":"84","author":"Girodeau","year":"2003","journal-title":"J Radiol"},{"key":"10.1016\/j.blre.2013.12.002_bb0370","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1056\/NEJMcpc059012","article-title":"Case records of the Massachusetts General Hospital. Case 17-2005. A 22-year-old woman with back and leg pain and respiratory failure","volume":"352","author":"Medoff","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0375","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00277-008-0491-y","article-title":"Fat emboli unleashed: an exceptional etiology of encephalitis in sickle cell disease","volume":"87","author":"Loupy","year":"2008","journal-title":"Ann Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0380","first-page":"E199","article-title":"Fat emboli syndrome: a cause of sudden death in a sickle cell patient","volume":"84","author":"Adams-Graves","year":"2009","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0385","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1002\/ajh.21605","article-title":"Fatal bone marrow embolism in a child with hemoglobin SE disease","volume":"85","author":"Rayburg","year":"2010","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0390","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1148\/rg.325115055","article-title":"AIRP best cases in radiologic-pathologic correlation: cerebral fat embolism syndrome in sickle cell \u03b2-thalassemia","volume":"32","author":"Gibbs","year":"2012","journal-title":"Radiographics"},{"key":"10.1016\/j.blre.2013.12.002_bb0395","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1177\/197140091202500403","article-title":"Cerebral fat embolism detection with susceptibility-weighted images in sickle cell disease","volume":"25","author":"Medina","year":"2012","journal-title":"Neuroradiol J"},{"key":"10.1016\/j.blre.2013.12.002_bb0400","first-page":"46","article-title":"Bone marrow necrosis and systemic fat embolism in sickle cell disease: the \u2018protective\u2019 role of the SS genotype and a possible association with parvovirus B19 infection","volume":"161","author":"Tsitsikas","year":"2013","journal-title":"Br J Haematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0405","article-title":"Unusual cutaneous lesions indicating fat embolism syndrome in homozygous sickle cell disease","author":"Bachmeyer","year":"2013","journal-title":"Am J Hematol"},{"key":"10.1016\/j.blre.2013.12.002_bb0410","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00000441-198803000-00009","article-title":"Aplastic crisis in sickle cell disorders: bone marrow necrosis and human parvovirus infection","volume":"295","author":"Conrad","year":"1988","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.blre.2013.12.002_bb0415","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0002-9343(91)90198-7","article-title":"Aplastic crisis due to extensive bone marrow necrosis and human parvovirus infection in sickle cell disease","volume":"91","author":"Godeau","year":"1991","journal-title":"Am J Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0420","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0248-8663(05)82134-4","article-title":"Multiple etiologies of extensive bone marrow necrosis in a patient with sickle cell disease","volume":"15","author":"Rose","year":"1994","journal-title":"Rev Med Interne"},{"key":"10.1016\/j.blre.2013.12.002_bb0425","first-page":"400","article-title":"Severe sickle cell anemia revealed in an adult by medullary necrosis","volume":"31","author":"Hocqueloux","year":"2002","journal-title":"Presse Med"},{"key":"10.1016\/j.blre.2013.12.002_bb0430","first-page":"179","article-title":"Extensive bone marrow necrosis as presenting manifestation of sickle cell disease in Africa","volume":"64","author":"Simon","year":"2004","journal-title":"Med Trop (Mars)"},{"key":"10.1016\/j.blre.2013.12.002_bb0435","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0761-8417(06)75439-6","article-title":"Acute chest syndrome as the inaugural sign of sickle cell anemia. A case report and review of the literature","volume":"62","author":"El Mekki","year":"2006","journal-title":"Rev Pneumol Clin"},{"key":"10.1016\/j.blre.2013.12.002_bb0440","first-page":"ECR18","article-title":"Fatal fungal superinfection complicating B19 virus-induced massive bone marrow necrosis in sickle-cell disease","volume":"91","author":"Fartoukh","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.blre.2013.12.002_bb0445","first-page":"211","article-title":"Bone marrow necrosis in sickle cell anaemia","volume":"8","author":"Ziakas","year":"2010","journal-title":"Blood Transfus"},{"key":"10.1016\/j.blre.2013.12.002_bb0450","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/ajh.21868","article-title":"Bone marrow necrosis and sickle cell crisis associated with double heterozygosity for HbS and HbOARAB","volume":"86","author":"Rossi","year":"2011","journal-title":"Am J Hematol"}],"container-title":["Blood Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0268960X14000022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0268960X14000022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T01:14:38Z","timestamp":1716426878000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0268960X14000022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0268960X14000022"],"URL":"https:\/\/doi.org\/10.1016\/j.blre.2013.12.002","relation":{},"ISSN":["0268-960X"],"issn-type":[{"value":"0268-960X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bone marrow necrosis and fat embolism syndrome in sickle cell disease: Increased susceptibility of patients with non-SS genotypes and a possible association with human parvovirus B19 infection","name":"articletitle","label":"Article Title"},{"value":"Blood Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.blre.2013.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}