{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T01:25:07Z","timestamp":1778808307512,"version":"3.51.4"},"reference-count":51,"publisher":"Elsevier BV","issue":"22","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.bmc.2005.06.051","type":"journal-article","created":{"date-parts":[[2005,8,4]],"date-time":"2005-08-04T15:57:38Z","timestamp":1123171058000},"page":"6244-6251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: Further evidence for the existence of an abnormal pathway for heme biosynthesis"],"prefix":"10.1016","volume":"13","author":[{"given":"Christopher L.","family":"Cooper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian M.","family":"Stob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie A.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy D.","family":"Lash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2005.06.051_bib1","series-title":"Biosynthesis of Tetrapyrroles","year":"1991"},{"key":"10.1016\/j.bmc.2005.06.051_bib2","volume":"Vol. 12","year":"2003"},{"key":"10.1016\/j.bmc.2005.06.051_bib3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1098\/rstb.1976.0009","volume":"273","author":"Jackson","year":"1976","journal-title":"Phil. Trans. R. Soc. Lond. B"},{"key":"10.1016\/j.bmc.2005.06.051_bib4","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1021\/jo9814748","volume":"64","author":"Lash","year":"1999","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib5","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1021\/jo981473f","volume":"64","author":"Lash","year":"1999","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib6","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1042\/bj2780901","volume":"278","author":"Lash","year":"1991","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib7_1","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0021-9258(19)77427-4","volume":"232","author":"Mauzerall","year":"1958","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib7_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-4165(64)90002-9","volume":"82","author":"Battle","year":"1964","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bmc.2005.06.051_bib7_3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0304-4165(68)90074-3","volume":"158","author":"San Martin de Viale","year":"1968","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bmc.2005.06.051_bib7_4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0014-5793(72)80573-8","volume":"26","author":"Frydman","year":"1972","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmc.2005.06.051_bib7_5","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1365-2133.1975.tb06494.x","volume":"93","author":"Smith","year":"1975","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.bmc.2005.06.051_bib8_1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0045-2068(80)90034-6","volume":"9","author":"Jackson","year":"1980","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib8_2","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.3987\/S-1981-02-1199","volume":"15","author":"Chakrabarty","year":"1981","journal-title":"Heterocycles"},{"key":"10.1016\/j.bmc.2005.06.051_bib9","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1071\/CH9760393","volume":"29","author":"Clezy","year":"1976","journal-title":"Aust. J. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib10","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1039\/p19760001008","author":"Battersby","year":"1976","journal-title":"J. Chem. Soc., Perkin Trans. 1"},{"key":"10.1016\/j.bmc.2005.06.051_bib11","first-page":"193","volume":"14","author":"Jackson","year":"1977","journal-title":"Sem. Hematol."},{"key":"10.1016\/j.bmc.2005.06.051_bib12","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/0020-711X(80)90216-5","volume":"12","author":"Smith","year":"1980","journal-title":"Int. J. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib13_1","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1080\/01483918308066552","volume":"6","author":"Lim","year":"1983","journal-title":"J. Liq. Chromatogr."},{"key":"10.1016\/j.bmc.2005.06.051_bib13_2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0021-9673(00)91640-6","volume":"282","author":"Lim","year":"1983","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.bmc.2005.06.051_bib13_3","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/bj2430621","volume":"243","author":"Li","year":"1987","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib13_4","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1042\/bj2470229","volume":"247","author":"Lim","year":"1987","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib14_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1042\/bj2680513","volume":"268","author":"Luo","year":"1990","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib14_2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0378-4347(91)80257-D","volume":"566","author":"Luo","year":"1991","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.bmc.2005.06.051_bib15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/bj2890529","volume":"289","author":"Luo","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib16","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1042\/bj1690215","volume":"169","author":"Elder","year":"1978","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/0020-711X(80)90144-5","volume":"12","author":"Jackson","year":"1980","journal-title":"Int. J. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib18_1","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1039\/p19740001188","author":"Cavaleiro","year":"1974","journal-title":"J. Chem. Soc., Perkin Trans. 1"},{"key":"10.1016\/j.bmc.2005.06.051_bib18_2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0021-9673(00)93830-5","volume":"125","author":"Evans","year":"1976","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.bmc.2005.06.051_bib19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0014-5793(70)80027-8","volume":"6","author":"Kennedy","year":"1970","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmc.2005.06.051_bib20","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1042\/bj2270327","volume":"227","author":"Jackson","year":"1985","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib21_1","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1042\/bj1260877","volume":"126","author":"Elder","year":"1972","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib21_2","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1136\/jcp.28.8.601","volume":"28","author":"Elder","year":"1975","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.bmc.2005.06.051_bib22","first-page":"227","volume":"14","author":"Elder","year":"1977","journal-title":"Sem. Hematol."},{"key":"10.1016\/j.bmc.2005.06.051_bib23","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1042\/bj1310429","volume":"131","author":"Stoll","year":"1973","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib24","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/0040-4020(76)85176-9","volume":"32","author":"Baptista de Almeida","year":"1976","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmc.2005.06.051_bib25","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1071\/CH9761561","volume":"29","author":"Clezy","year":"1976","journal-title":"Aust. J. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib26","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1039\/p19870000287","author":"Jackson","year":"1987","journal-title":"J. Chem. Soc., Perkin Trans. 1"},{"key":"10.1016\/j.bmc.2005.06.051_bib27","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1042\/bst0051472","volume":"5","author":"Smith","year":"1977","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bmc.2005.06.051_bib28","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1042\/bj1690205","volume":"169","author":"Elder","year":"1978","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib29","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0020-711X(80)90161-5","volume":"12","author":"Jackson","year":"1980","journal-title":"Int. J. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib30","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1042\/bj2730246","volume":"273","author":"Kurlandzka","year":"1991","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2005.06.051_bib31","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/0020-711X(78)90063-0","volume":"9","author":"Jackson","year":"1978","journal-title":"Int. J. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib32","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/S0960-894X(01)80575-8","volume":"4","author":"Lash","year":"1994","journal-title":"BioMed. Chem. Lett."},{"key":"10.1016\/j.bmc.2005.06.051_bib33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0960-894X(01)00701-6","volume":"12","author":"Lash","year":"2002","journal-title":"BioMed. Chem. Lett."},{"key":"10.1016\/j.bmc.2005.06.051_bib34","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1021\/jo001697+","volume":"66","author":"Lash","year":"2001","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib35","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1093\/oxfordjournals.jbchem.a003088","volume":"131","author":"Jones","year":"2002","journal-title":"J. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib36","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/S0960-894X(02)00097-5","volume":"12","author":"Lash","year":"2002","journal-title":"BioMed. Chem. Lett."},{"key":"10.1016\/j.bmc.2005.06.051_bib37","doi-asserted-by":"crossref","first-page":"32507","DOI":"10.1074\/jbc.271.51.32507","volume":"271","author":"Medlock","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2005.06.051_bib38","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bmc.2005.06.051_bib39","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2005.06.051_bib40","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0165-022X(03)00078-2","volume":"55","author":"Jones","year":"2003","journal-title":"J. Biochem. Biophys."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089605005870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089605005870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T22:54:27Z","timestamp":1760828067000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089605005870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":51,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0968089605005870"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2005.06.051","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: Further evidence for the existence of an abnormal pathway for heme biosynthesis","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2005.06.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}