{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:59:34Z","timestamp":1788350374789,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.bmc.2007.01.002","type":"journal-article","created":{"date-parts":[[2007,1,5]],"date-time":"2007-01-05T08:58:59Z","timestamp":1167987539000},"page":"1959-1966","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation"],"prefix":"10.1016","volume":"15","author":[{"given":"Mona A.","family":"Maalouf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Wiemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig H.","family":"Kuder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond J.","family":"Hohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David F.","family":"Wiemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2007.01.002_bib1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2174\/156800906775471743","volume":"6","author":"Swanson","year":"2006","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.bmc.2007.01.002_bib2","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1210\/er.2001-3002","volume":"23","author":"Cranney","year":"2002","journal-title":"Endocr. Rev."},{"issue":"Suppl. 3","key":"10.1016\/j.bmc.2007.01.002_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ctrv.2005.09.003","volume":"31","author":"Hortobagyi","year":"2005","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.bmc.2007.01.002_bib4","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0968-0896(98)00034-0","volume":"6","author":"Holstein","year":"1998","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib5","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1016\/j.jorganchem.2004.10.013","volume":"690","author":"Shull","year":"2005","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib6","doi-asserted-by":"crossref","first-page":"8665","DOI":"10.1016\/S0040-4039(02)02148-2","volume":"43","author":"Du","year":"2002","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmc.2007.01.002_bib7","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1016\/j.bmc.2006.02.010","volume":"14","author":"Shull","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib8","unstructured":"Reported in part at the 2005 American Society for Clinical Oncology meeting, cf: Swanson, K. M.; Tong, H.; Wiemer, A. J.; Murthy, S.; Hohl, R. J. J. Clin. Oncol. 2005, 23, 581S."},{"key":"10.1016\/j.bmc.2007.01.002_bib9","first-page":"711","volume":"4","author":"Reszka","year":"2004","journal-title":"Mini-Rev. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib10","doi-asserted-by":"crossref","first-page":"5804","DOI":"10.1021\/jm060280e","volume":"49","author":"Zhang","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib11","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1359\/jbmr.1998.13.4.581","volume":"13","author":"Luckman","year":"1998","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bmc.2007.01.002_bib12","doi-asserted-by":"crossref","first-page":"24832","DOI":"10.1016\/S0021-9258(19)74540-2","volume":"268","author":"Ciosek","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1006\/abbi.1999.1502","volume":"373","author":"Bergsrtom","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bmc.2007.01.002_bib14","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1006\/bbrc.1999.1499","volume":"263","author":"van Beek","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bmc.2007.01.002_bib15","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/cmdc.200500059","volume":"1","author":"Rondeau","year":"2006","journal-title":"Chem. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib16","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1006\/bbrc.2001.6289","volume":"290","author":"Thompson","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bmc.2007.01.002_bib17","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1021\/jm010412y","volume":"45","author":"Szabo","year":"2002","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib18","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1016\/S0024-3205(03)00664-7","volume":"73","author":"Nishida","year":"2003","journal-title":"Life Sci."},{"key":"10.1016\/j.bmc.2007.01.002_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0378-4347(93)E0397-9","volume":"652","author":"Usui","year":"1994","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.bmc.2007.01.002_bib20","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S1076-6332(03)00253-8","volume":"10","author":"Lenkinski","year":"2003","journal-title":"Acad. Radiol."},{"key":"10.1016\/j.bmc.2007.01.002_bib21","doi-asserted-by":"crossref","first-page":"5526","DOI":"10.1021\/ja00458a072","volume":"99","author":"Umbreit","year":"1977","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2007.01.002_bib22","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1021\/jo960057x","volume":"61","author":"Abdel-Magid","year":"1996","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib23","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0040-4039(01)92575-4","volume":"18","author":"McKenna","year":"1977","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmc.2007.01.002_bib24","doi-asserted-by":"crossref","first-page":"8186","DOI":"10.1021\/jo049101w","volume":"69","author":"Kim","year":"2004","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib25","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1021\/ja00107a011","volume":"117","author":"Zheng","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2007.01.002_bib26","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ab.2004.09.024","volume":"336","author":"Tong","year":"2005","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2007.01.002_bib27","doi-asserted-by":"crossref","first-page":"22004","DOI":"10.1074\/jbc.M602603200","volume":"281","author":"Kavanagh","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib28","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1039\/j39700000235","author":"Pattenden","year":"1970","journal-title":"J. Chem. Soc. C"},{"key":"10.1016\/j.bmc.2007.01.002_bib29","doi-asserted-by":"crossref","first-page":"17508","DOI":"10.1074\/jbc.270.29.17508","volume":"270","author":"Hohl","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2007.01.002_bib30","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1172\/JCI111083","volume":"72","author":"Larson","year":"1983","journal-title":"J. Clin. Invest."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089607000041?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089607000041?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:04:57Z","timestamp":1760828697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089607000041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0968089607000041"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2007.01.002","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2007.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}