{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:48:32Z","timestamp":1790434112139,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.bmc.2008.06.052","type":"journal-article","created":{"date-parts":[[2008,7,3]],"date-time":"2008-07-03T07:57:52Z","timestamp":1215071872000},"page":"7107-7116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells"],"prefix":"10.1016","volume":"16","author":[{"given":"Ingo","family":"Ott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte","family":"Kokoschka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Harlos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Sheldrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhong","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2008.06.052_bib1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.2174\/1568011013354624","volume":"1","author":"Brana","year":"2001","journal-title":"Curr. Med. Chem. Anti-Cancer Agents"},{"key":"10.1016\/j.bmc.2008.06.052_bib2","first-page":"17","volume":"5","author":"Idoipe","year":"1979","journal-title":"Arch. Farmacol. Toxicol."},{"key":"10.1016\/j.bmc.2008.06.052_bib3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF00255461","volume":"4","author":"Brana","year":"1980","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.bmc.2008.06.052_bib4","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1021\/jm00147a016","volume":"28","author":"Zee-Cheng","year":"1985","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib5","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1021\/jm9905817","volume":"43","author":"Sami","year":"2000","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib6","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1039\/b209042b","volume":"1","author":"Brana","year":"2003","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib7","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1021\/jm0308850","volume":"47","author":"Brana","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib8","doi-asserted-by":"crossref","first-page":"7198","DOI":"10.1021\/jm0606793","volume":"49","author":"Antonini","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib9","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.1021\/jm070315q","volume":"50","author":"Quaquebeke","year":"2007","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib10","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1016\/j.bmcl.2005.04.012","volume":"15","author":"Li","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib11","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1016\/j.bmc.2005.05.006","volume":"13","author":"Li","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib12","doi-asserted-by":"crossref","first-page":"5114","DOI":"10.1016\/j.bmc.2007.05.032","volume":"15","author":"Li","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib13","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1158\/1535-7163.MCT-06-0584","volume":"6","author":"Zhu","year":"2007","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.bmc.2008.06.052_bib14","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0047-2670(87)80023-0","volume":"36","author":"Pardo","year":"1987","journal-title":"J. Photochem."},{"key":"10.1016\/j.bmc.2008.06.052_bib15","doi-asserted-by":"crossref","first-page":"4929","DOI":"10.1021\/jo050157f","volume":"70","author":"Cao","year":"2005","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib16","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1016\/j.bmcl.2004.02.059","volume":"14","author":"Qian","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib17","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.bmcl.2005.02.053","volume":"15","author":"Li","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib18","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.bmcl.2004.12.011","volume":"15","author":"Xu","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib19","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.bmc.2004.12.012","volume":"13","author":"Yang","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib20","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1562\/0031-8655(2001)074<0521:MOPCOD>2.0.CO;2","volume":"74","author":"Rogers","year":"2001","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.bmc.2008.06.052_bib21","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1089\/aid.1993.9.891","volume":"9","author":"Chanh","year":"1993","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"10.1016\/j.bmc.2008.06.052_bib22","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0166-3542(94)90102-3","volume":"25","author":"Chanh","year":"1994","journal-title":"Antiviral Res."},{"key":"10.1016\/j.bmc.2008.06.052_bib23","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1096\/fj.00-0555rev","volume":"15","author":"Pervaiz","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.bmc.2008.06.052_bib24","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1039\/a908787g","author":"Qian","year":"2000","journal-title":"J. Chem. Soc. Perkin. Trans. 2"},{"key":"10.1016\/j.bmc.2008.06.052_bib25","doi-asserted-by":"crossref","first-page":"11824","DOI":"10.1021\/jp000333i","volume":"104","author":"Ramachandram","year":"2000","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bmc.2008.06.052_bib26","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s10895-005-0215-9","volume":"15","author":"Ramachandram","year":"2005","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.bmc.2008.06.052_bib27","doi-asserted-by":"crossref","first-page":"11062","DOI":"10.1021\/jp057557r","volume":"110","author":"Cho","year":"2006","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bmc.2008.06.052_bib28","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1002\/ejic.200700206","author":"Sch\u00e4fer","year":"2007","journal-title":"Eur. J. Inorg. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib29","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1010-6030(03)00100-X","volume":"158","author":"Grabchev","year":"2003","journal-title":"J. Photochem. Photobiol. A"},{"key":"10.1016\/j.bmc.2008.06.052_bib30","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1021\/ol051131d","volume":"7","author":"Xu","year":"2005","journal-title":"Org. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib31","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1021\/tx0501536","volume":"18","author":"Zhang","year":"2005","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.bmc.2008.06.052_bib32","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1021\/ol0473445","volume":"7","author":"Xu","year":"2005","journal-title":"Org. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib33","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1039\/B614529A","volume":"5","author":"Parkesh","year":"2007","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib34","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1021\/ol049005h","volume":"6","author":"Cui","year":"2004","journal-title":"Org. Lett."},{"key":"10.1016\/j.bmc.2008.06.052_bib35","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0022-2313(96)00008-7","volume":"68","author":"Martin","year":"1996","journal-title":"J. Lumin."},{"key":"10.1016\/j.bmc.2008.06.052_bib36","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1021\/jm0307887","volume":"46","author":"Berque-Bestel","year":"2003","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib37","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1021\/ja0449168","volume":"127","author":"Vazquez","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2008.06.052_bib38","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1021\/jm049326z","volume":"48","author":"Ott","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib39","doi-asserted-by":"crossref","first-page":"3653","DOI":"10.1021\/jm060343t","volume":"49","author":"Vazquez","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.06.052_bib40","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1002\/lsm.20338","volume":"38","author":"Muller","year":"2006","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.bmc.2008.06.052_bib41","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/jnci\/90.12.889","volume":"90","author":"Dougherty","year":"1998","journal-title":"J. Nat. Cancer Inst."},{"key":"10.1016\/j.bmc.2008.06.052_bib42","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1039\/c39950001787","author":"Liu","year":"1995","journal-title":"J. Chem. Soc., Chem. Commun."},{"key":"10.1016\/j.bmc.2008.06.052_bib43","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0022-2836(61)80047-8","volume":"3","author":"Marmur","year":"1961","journal-title":"J. Mol. Biol."}],"container-title":["Bioorganic &amp; Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608005981?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608005981?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:25:15Z","timestamp":1760829915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089608005981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":43,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0968089608005981"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2008.06.052","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2008.06.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}