{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:58:32Z","timestamp":1790261912502,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"21","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.bmc.2008.09.052","type":"journal-article","created":{"date-parts":[[2008,9,21]],"date-time":"2008-09-21T09:41:42Z","timestamp":1221990102000},"page":"9432-9442","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Synthesis and anti-inflammatory structure\u2013activity relationships of thiazine\u2013quinoline\u2013quinones: Inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis"],"prefix":"10.1016","volume":"16","author":[{"given":"Elizabeth W.","family":"Chia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Norrie","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael V.","family":"Berridge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel B.","family":"Perry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine E.","family":"Sansom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colette A.","family":"Godfrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyall R.","family":"Hanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Liang (Leon)","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Walton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Denny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent R.","family":"Copp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquie L.","family":"Harper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2008.09.052_bib1","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1196\/annals.1326.018","volume":"1072","author":"Chin","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bmc.2008.09.052_bib2","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1093\/rheumatology\/keh640","volume":"44","author":"Dalbeth","year":"2005","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.bmc.2008.09.052_bib3","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1136\/thorax.57.7.643","volume":"57","author":"Douwes","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.bmc.2008.09.052_bib4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.atherosclerosis.2007.08.014","volume":"197","author":"Mazor","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bmc.2008.09.052_bib5","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1002\/art.23545","volume":"58","author":"Smith","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bmc.2008.09.052_bib6","first-page":"194","volume":"4","author":"Partrick","year":"1996","journal-title":"New Horiz."},{"key":"10.1016\/j.bmc.2008.09.052_bib7","first-page":"886","volume":"3","author":"Salvemini","year":"2002","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"10.1016\/j.bmc.2008.09.052_bib8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/00024382-199411000-00001","volume":"2","author":"Varani","year":"1994","journal-title":"Shock"},{"key":"10.1016\/j.bmc.2008.09.052_bib9","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1021\/np060626o","volume":"70","author":"Pearce","year":"2007","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.bmc.2008.09.052_bib10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/cber.19520850202","volume":"85","author":"Teuber","year":"1952","journal-title":"Chem. Ber."},{"key":"10.1016\/j.bmc.2008.09.052_bib11","doi-asserted-by":"crossref","first-page":"7733","DOI":"10.1021\/jm050758z","volume":"48","author":"Hassani","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.09.052_bib12","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/S0040-4039(00)80294-4","volume":"29","author":"Schrader","year":"1988","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmc.2008.09.052_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0022-328X(91)86210-H","volume":"401","author":"Yoneda","year":"1991","journal-title":"J. Organometal. Chem."},{"key":"10.1016\/j.bmc.2008.09.052_bib14","doi-asserted-by":"crossref","first-page":"3922","DOI":"10.1021\/jo00252a007","volume":"53","author":"Schmitz","year":"1988","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.09.052_bib15","unstructured":"Denny, W. A.; Copp, B. R.; Pearce, A. N.; Berridge, M. V.; Harper, J. L.; Perry, N. B.; Larsen, L.; Godfrey, C. A. 2005. Patent Application WO 2006031134 (Chem. Abs. AN 2006:269600)."},{"key":"10.1016\/j.bmc.2008.09.052_bib16","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1021\/ic00032a001","volume":"31","author":"Sayre","year":"1992","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.bmc.2008.09.052_bib17","doi-asserted-by":"crossref","first-page":"4329","DOI":"10.1016\/S0040-4039(01)00727-4","volume":"42","author":"Cossy","year":"2001","journal-title":"Tetrahedron Lett."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608008882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608008882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:24:28Z","timestamp":1760829868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089608008882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":17,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0968089608008882"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2008.09.052","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and anti-inflammatory structure\u2013activity relationships of thiazine\u2013quinoline\u2013quinones: Inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2008.09.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}