{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:40:53Z","timestamp":1760834453800,"version":"build-2065373602"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.bmc.2008.11.071","type":"journal-article","created":{"date-parts":[[2008,12,7]],"date-time":"2008-12-07T05:41:00Z","timestamp":1228628460000},"page":"553-557","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors"],"prefix":"10.1016","volume":"17","author":[{"given":"Anne","family":"Thiry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Ledecq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Cecchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Frederick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Michel","family":"Dogn\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Wouters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Masereel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2008.11.071_bib1a","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0968-0004(98)01344-9","volume":"24","author":"Dang","year":"1999","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bmc.2008.11.071_bib1b","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.humpath.2006.07.020","volume":"38","author":"Korkolopoulou","year":"2007","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.bmc.2008.11.071_bib2","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.tips.2006.09.002","volume":"27","author":"Thiry","year":"2006","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bmc.2008.11.071_bib3","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1021\/jm701526d","volume":"51","author":"Thiry","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.11.071_bib4","doi-asserted-by":"crossref","first-page":"865","DOI":"10.2174\/156802607780636708","volume":"7","author":"Pastorekova","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bmc.2008.11.071_bib5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0065-2423(06)42005-9","volume":"42","author":"Pastorekova","year":"2006","journal-title":"Adv. Clin. Chem."},{"key":"10.1016\/j.bmc.2008.11.071_bib6","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Discovery"},{"key":"10.1016\/j.bmc.2008.11.071_bib7","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1021\/ci700214j","volume":"47","author":"Tuccinardi","year":"2007","journal-title":"J. Chem. Inf. Model."},{"year":"2003","series-title":"Molecular Modeling: basic principles and applications","author":"H\u00f6ltje","key":"10.1016\/j.bmc.2008.11.071_bib8"},{"key":"10.1016\/j.bmc.2008.11.071_bib9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1021\/ci049714+","volume":"45","author":"Irwin","year":"2005","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.bmc.2008.11.071_bib10","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1021\/jm0600287","volume":"49","author":"Thiry","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2008.11.071_bib11","unstructured":"ChemicalComputingGroup MOE: Molecular Operating Environment, versions 2005.06 ed."},{"key":"10.1016\/j.bmc.2008.11.071_bib12a","doi-asserted-by":"crossref","first-page":"5427","DOI":"10.1016\/j.bmcl.2004.07.087","volume":"14","author":"Garaj","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib12b","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.bmcl.2004.10.070","volume":"15","author":"Turkmen","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib12c","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0960-894X(03)00091-X","volume":"13","author":"Vullo","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib12d","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1016\/j.bmcl.2004.01.095","volume":"14","author":"Vullo","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib12e","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1016\/j.bmc.2005.11.019","volume":"14","author":"Vullo","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib12f","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1016\/j.bmcl.2005.02.091","volume":"15","author":"Winum","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.11.071_bib13","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1006\/jmbi.1996.0897","volume":"267","author":"Jones","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmc.2008.11.071_bib14","unstructured":"DeLano, W.L. In The PyMOL Molecular Graphics System; DeLano Scientific: Palo Alto, CA, USA."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608011644?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089608011644?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:28:30Z","timestamp":1760830110000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089608011644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0968089608011644"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2008.11.071","relation":{},"ISSN":["0968-0896"],"issn-type":[{"type":"print","value":"0968-0896"}],"subject":[],"published":{"date-parts":[[2009,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2008.11.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}