{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:51:26Z","timestamp":1767905486178,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.bmc.2008.12.042","type":"journal-article","created":{"date-parts":[[2008,12,26]],"date-time":"2008-12-26T04:33:58Z","timestamp":1230266038000},"page":"1152-1157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Function-oriented synthesis applied to the anti-botulinum natural product toosendanin"],"prefix":"10.1016","volume":"17","author":[{"given":"Yuya","family":"Nakai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William H.","family":"Tepp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobin J.","family":"Dickerson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim D.","family":"Janda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2008.12.042_bib1","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/S0041-0101(01)00157-X","volume":"39","author":"Johnson","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.bmc.2008.12.042_bib2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1128\/mr.56.1.80-99.1992","volume":"56","author":"Schantz","year":"1992","journal-title":"Microbiol. Rev."},{"key":"10.1016\/j.bmc.2008.12.042_bib3","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev.pharmtox.44.101802.121554","volume":"44","author":"Simpson","year":"2004","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.bmc.2008.12.042_bib4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1021\/cb600179d","volume":"1","author":"Dickerson","year":"2006","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.bmc.2008.12.042_bib5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0272-2712(18)30023-4","volume":"21","author":"Madsen","year":"2001","journal-title":"Clin. Lab. Med."},{"key":"10.1016\/j.bmc.2008.12.042_bib6","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1001\/jama.1997.03550050074036","volume":"278","author":"Christopher","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.bmc.2008.12.042_bib7","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1001\/jama.1997.03550050080037","volume":"278","author":"Zilinskas","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.bmc.2008.12.042_bib8a","doi-asserted-by":"crossref","first-page":"6463","DOI":"10.1016\/j.bmcl.2007.09.103","volume":"17","author":"\u010capkov\u00e1","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2008.12.042_bib8b","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1039\/b603099h","author":"Boldt","year":"2006","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bmc.2008.12.042_bib8c","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1021\/ol0603211","volume":"8","author":"Boldt","year":"2006","journal-title":"Org. Lett."},{"key":"10.1016\/j.bmc.2008.12.042_bib8d","doi-asserted-by":"crossref","first-page":"2602","DOI":"10.1073\/pnas.0611213104","volume":"104","author":"Eubanks","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmc.2008.12.042_bib8e","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.chembiol.2007.03.014","volume":"14","author":"Silvaggi","year":"2007","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.bmc.2008.12.042_bib9","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3987\/REV-98-SR(H)5","volume":"50","author":"Nakatani","year":"1999","journal-title":"Heterocycles"},{"key":"10.1016\/j.bmc.2008.12.042_bib10","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1271\/bbb.66.1731","volume":"66","author":"Carpinella","year":"2002","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.bmc.2008.12.042_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0022-474X(95)00003-P","volume":"31","author":"Xie","year":"1995","journal-title":"J. Stored. Prod. Res."},{"key":"10.1016\/j.bmc.2008.12.042_bib12a","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1023\/A:1024802328458","volume":"29","author":"Akhtar","year":"2003","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.bmc.2008.12.042_bib12b","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1021\/jf025811w","volume":"51","author":"Carpinella","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib12c","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.3987\/REV-96-487","volume":"45","author":"Zhou","year":"1997","journal-title":"Heterocycles"},{"key":"10.1016\/j.bmc.2008.12.042_bib13a","first-page":"28","volume":"13","author":"Li","year":"1982","journal-title":"Zhongcaoyao"},{"key":"10.1016\/j.bmc.2008.12.042_bib13b","first-page":"29","volume":"5","author":"Zou","year":"1985","journal-title":"J. Trad. Chin. Med."},{"key":"10.1016\/j.bmc.2008.12.042_bib14","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1021\/ar700155p","volume":"41","author":"Wender","year":"2008","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.bmc.2008.12.042_bib15","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1021\/jo0301346","volume":"68","author":"Paquette","year":"2003","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib16","doi-asserted-by":"crossref","first-page":"9440","DOI":"10.1021\/jo981456q","volume":"63","author":"Fernandez-Mateos","year":"1998","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib17","doi-asserted-by":"crossref","first-page":"12264","DOI":"10.1016\/j.tet.2005.09.109","volume":"61","author":"Fernandez-Mateos","year":"2005","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmc.2008.12.042_bib18","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0040-4020(00)01092-9","volume":"57","author":"Fernandez-Mateos","year":"2001","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmc.2008.12.042_bib19","doi-asserted-by":"crossref","first-page":"9097","DOI":"10.1021\/jo961100j","volume":"61","author":"Fernandez-Mateos","year":"1996","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib20","doi-asserted-by":"crossref","first-page":"3580","DOI":"10.1021\/jo00117a005","volume":"60","author":"Fernandez-Mateos","year":"1995","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib21","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1055\/s-1997-1365","author":"Fernandez-Mateos","year":"1997","journal-title":"Synthesis"},{"key":"10.1016\/j.bmc.2008.12.042_bib22","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1021\/jo0205311","volume":"68","author":"Fernandez-Mateos","year":"2003","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2008.12.042_bib23","doi-asserted-by":"crossref","first-page":"14131","DOI":"10.1016\/S0040-4020(97)00915-0","volume":"53","author":"Fernandez-Mateos","year":"1997","journal-title":"Tetrahedron"}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096808960801211X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096808960801211X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:33:06Z","timestamp":1760830386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096808960801211X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S096808960801211X"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2008.12.042","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Function-oriented synthesis applied to the anti-botulinum natural product toosendanin","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2008.12.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}