{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T08:20:16Z","timestamp":1771575616735,"version":"3.50.1"},"reference-count":56,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1016\/j.bmc.2010.03.082","type":"journal-article","created":{"date-parts":[[2010,4,12]],"date-time":"2010-04-12T03:22:40Z","timestamp":1271042560000},"page":"3559-3563","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II"],"prefix":"10.1016","volume":"18","author":[{"given":"Deniz","family":"Ekinci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fcseyin","family":"\u00c7avdar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktay","family":"Talaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"\u015eent\u00fcrk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2010.03.082_bib1_1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmc.2010.03.082_bib1_2","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1016\/j.bmc.2007.04.020","volume":"15","author":"Supuran","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib1_3","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1517\/13543776.12.2.217","volume":"12","author":"Supuran","year":"2002","journal-title":"Expert Opin. Ther. Patents"},{"key":"10.1016\/j.bmc.2010.03.082_bib2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1146\/annurev.bi.64.070195.002111","volume":"64","author":"Sly","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bmc.2010.03.082_bib3_1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1023\/B:BIRY.0000018954.38006.9a","volume":"69","author":"Ozensoy","year":"2004","journal-title":"Biochemistry (Moscow)"},{"key":"10.1016\/j.bmc.2010.03.082_bib3_2","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/ja809683v","volume":"131","author":"Maresca","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2010.03.082_bib4a","series-title":"Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications","first-page":"73","article-title":"X-Ray Crystallography of CA Inhibitors and its Importance in Drug Design","author":"Alterio","year":"2009"},{"key":"10.1016\/j.bmc.2010.03.082_bib4_2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/14756360410001689540","volume":"19","author":"Pastorekova","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib5_1","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.bmcl.2008.01.077","volume":"18","author":"Innocenti","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib5_2","doi-asserted-by":"crossref","first-page":"7424","DOI":"10.1016\/j.bmc.2008.06.013","volume":"16","author":"Innocenti","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib5_3","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1016\/j.bmcl.2008.04.077","volume":"18","author":"Innocenti","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib6_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1042\/BJ20051102","volume":"392","author":"Hilvo","year":"2005","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2010.03.082_bib6_2","doi-asserted-by":"crossref","first-page":"16233","DOI":"10.1073\/pnas.0908301106","volume":"106","author":"Alterio","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmc.2010.03.082_bib7_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.pestbp.2009.07.005","volume":"95","author":"Senturk","year":"2009","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.bmc.2010.03.082_bib7_2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1080\/14756360701342581","volume":"23","author":"Senturk","year":"2008","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib7_3","unstructured":"Ceyhun, S.B.; Senturk, M.; Erdogan, O.; Kufrevioglu, O.I. Pestic. Biochem. Physiol. doi:10.1016\/j.pest.bp.2010.01.003."},{"key":"10.1016\/j.bmc.2010.03.082_bib8_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmc.2010.03.082_bib8_2","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1517\/13543776.16.12.1627","volume":"16","author":"Scozzafava","year":"2006","journal-title":"Expert Opin. Ther. Patents"},{"key":"10.1016\/j.bmc.2010.03.082_bib8_3","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2174\/156802607780636726","volume":"7","author":"Thiry","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib9_1","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1080\/14756360601176048","volume":"22","author":"Ekinci","year":"2007","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib9_2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1080\/14756360701474780","volume":"23","author":"Coban","year":"2008","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib9_3","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1248\/bpb.30.2257","volume":"30","author":"Coban","year":"2007","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.bmc.2010.03.082_bib9_4","first-page":"580","volume":"59","author":"Ekinci","year":"2007","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bmc.2010.03.082_bib10_1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2174\/138161208783877884","volume":"14","author":"Supuran","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmc.2010.03.082_bib10_2","doi-asserted-by":"crossref","first-page":"641","DOI":"10.2174\/138161208783877947","volume":"14","author":"Supuran","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmc.2010.03.082_bib10_3","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2174\/138161208783877848","volume":"14","author":"Winum","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmc.2010.03.082_bib11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00436-002-0754-9","volume":"90","author":"Raether","year":"2003","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.bmc.2010.03.082_bib12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1021\/ja0559101","volume":"128","author":"Anderson","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2010.03.082_bib13_1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1667\/RR0719.1","volume":"167","author":"Ljungkvist","year":"2007","journal-title":"Radiat. Res."},{"key":"10.1016\/j.bmc.2010.03.082_bib13_2","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/sj.clpt.6100213","volume":"81","author":"Nutt","year":"2007","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.bmc.2010.03.082_bib14","first-page":"494","volume":"271","author":"Arteel","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bmc.2010.03.082_bib15","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.1016\/j.bmcl.2005.05.030","volume":"15","author":"Mallia","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib16","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1016\/j.bmcl.2009.04.087","volume":"19","author":"Senturk","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib17","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.bmcl.2004.11.056","volume":"15","author":"Innocenti","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib18","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.bmcl.2005.02.088","volume":"15","author":"Almajan","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib19","doi-asserted-by":"crossref","first-page":"3230","DOI":"10.1021\/jm800121c","volume":"51","author":"D\u2019Ambrosio","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib20","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1021\/jm021124k","volume":"46","author":"Winum","year":"2003","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib21_1","doi-asserted-by":"crossref","first-page":"9101","DOI":"10.1016\/j.bmc.2008.09.028","volume":"16","author":"Bayram","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib21_2","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1016\/j.bmc.2009.01.067","volume":"17","author":"Senturk","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib21_3","first-page":"289","volume":"37","author":"Senturk","year":"2009","journal-title":"Hacettepe J. Biol. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib22","doi-asserted-by":"crossref","first-page":"6565","DOI":"10.1016\/j.bmcl.2009.10.036","volume":"19","author":"Steele","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib23","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1289\/ehp.8564199","volume":"64","author":"Moreno","year":"1985","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.bmc.2010.03.082_bib24","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0021-9258(18)51011-5","volume":"176","author":"Wilbur","year":"1976","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib25_1","doi-asserted-by":"crossref","first-page":"4221","DOI":"10.1016\/S0021-9258(18)95800-X","volume":"242","author":"Verpoorte","year":"1967","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib25_2","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/j.bmcl.2008.03.012","volume":"18","author":"Innocenti","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib26","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2010.03.082_bib27","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bmc.2010.03.082_bib28","first-page":"685","volume":"57","author":"Lineweaver","year":"1934","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2010.03.082_bib29","first-page":"121","volume":"122","author":"Vitale","year":"1999","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.bmc.2010.03.082_bib30","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S1095-6433(99)00070-7","volume":"23A","author":"Gervais","year":"1999","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.bmc.2010.03.082_bib31","volume":"vols. 3 and 4","author":"Hochster","year":"1973"},{"key":"10.1016\/j.bmc.2010.03.082_bib32","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0013-9351(82)90026-3","volume":"29","author":"Christensen","year":"1982","journal-title":"Environ. Res."},{"key":"10.1016\/j.bmc.2010.03.082_bib33_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.febslet.2004.10.043","volume":"577","author":"Svastova","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmc.2010.03.082_bib33_2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1517\/13543784.12.2.283","volume":"12","author":"Supuran","year":"2003","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.bmc.2010.03.082_bib33_3","doi-asserted-by":"crossref","first-page":"4834","DOI":"10.1021\/jm0501073","volume":"48","author":"Cecchi","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.03.082_bib34","unstructured":"Senturk, M., Kufrevioglu O.I., Preparation of new affinity gels for purifying human erythrocytes CA isozymes, IV. National Affinity Techniques Congress, 4\u20137 May 2008, p.37."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089610003123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089610003123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:43:35Z","timestamp":1760831015000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089610003123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":56,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0968089610003123"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2010.03.082","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2010.03.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}