{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:58:07Z","timestamp":1760853487634,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","issue":"21","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.bmc.2010.09.007","type":"journal-article","created":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T05:09:19Z","timestamp":1283922559000},"page":"7392-7401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors"],"prefix":"10.1016","volume":"18","author":[{"given":"S\u00e9bastien","family":"Gluszok","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rapha\u00ebl","family":"Fr\u00e9d\u00e9rick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Foulon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Klupsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Vullo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"Goossens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Masereel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Depreux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Goossens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2010.09.007_b0005","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmc.2010.09.007_b0010","doi-asserted-by":"crossref","first-page":"865","DOI":"10.2174\/156802607780636708","volume":"7","author":"Pastorekova","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0015","doi-asserted-by":"crossref","first-page":"685","DOI":"10.2174\/138161208783877893","volume":"14","author":"Pastorekova","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmc.2010.09.007_b0020","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s10555-007-9058-y","volume":"26","author":"Semenza","year":"2007","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.bmc.2010.09.007_b0030","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1016\/j.bmc.2007.04.020","volume":"15","author":"Supuran","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0035","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","volume":"20","author":"Supuran","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2010.09.007_b0045","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.tips.2006.09.002","volume":"27","author":"Thiry","year":"2006","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bmc.2010.09.007_b0155","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1124\/jpet.110.167270","volume":"334","author":"Cianchi","year":"2010","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"10.1016\/j.bmc.2010.09.007_b0055","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.radonc.2007.04.018","volume":"83","author":"Dubois","year":"2007","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.bmc.2010.09.007_b0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1357-4310(99)01615-9","volume":"6","author":"Stubbs","year":"2000","journal-title":"Mol. Med. Today"},{"key":"10.1016\/j.bmc.2010.09.007_b0065","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.febslet.2004.10.043","volume":"577","author":"Svastova","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmc.2010.09.007_b0070","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1021\/jm701526d","volume":"51","author":"Thiry","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0075","series-title":"Drug Design of Zinc-Enyme Inhibitors","first-page":"255","article-title":"Dual Carbonic Anhydrase and Cyclooxygenase-2 Inhibition","author":"Dogn\u00e9","year":"2009"},{"key":"10.1016\/j.bmc.2010.09.007_b0080","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1021\/jm030912m","volume":"47","author":"Weber","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0085","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.ejmech.2008.03.034","volume":"44","author":"Thiry","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0090","doi-asserted-by":"crossref","first-page":"16233","DOI":"10.1073\/pnas.0908301106","volume":"106","author":"Alterio","year":"2009","journal-title":"PNAS"},{"key":"10.1016\/j.bmc.2010.09.007_b0095","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.bmcl.2003.12.029","volume":"14","author":"Pastorekova","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0100","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.1021\/ol0063205","volume":"2","author":"Stauffer","year":"2000","journal-title":"Org. Lett."},{"key":"10.1016\/j.bmc.2010.09.007_b0105","doi-asserted-by":"crossref","first-page":"6087","DOI":"10.1016\/j.tetlet.2006.06.094","volume":"47","author":"Gluszok","year":"2006","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmc.2010.09.007_b0110","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1021\/jo961761g","volume":"62","author":"Pop","year":"1997","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0115","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1021\/cc0200282","volume":"4","author":"Gooding","year":"2002","journal-title":"J. Comb. Chem."},{"year":"2004","series-title":"Development of Sulfonamide Carbonic Anhydrase Inhibitors","author":"Supuran","key":"10.1016\/j.bmc.2010.09.007_b0120"},{"key":"10.1016\/j.bmc.2010.09.007_b0125","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmc.2010.09.007_b0130","unstructured":"ACD\/Structure Designer, version 12.0, Advanced Chemistry Development, Toronto ON, Canada, www.acdlabs.com, 2010."},{"year":"2001","series-title":"Pharmacokinetic Optimization in Drug Research","key":"10.1016\/j.bmc.2010.09.007_b0135"},{"key":"10.1016\/j.bmc.2010.09.007_b0140","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah","year":"1971","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2010.09.007_b0145","unstructured":"Tripos, I. SYBYL. 1699 South Hanley Rd., St. Louis, Missouri, 63144, USA."},{"key":"10.1016\/j.bmc.2010.09.007_b0150","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1006\/jmbi.1996.0897","volume":"267","author":"Jones","year":"1997","journal-title":"J. Mol. Biol."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089610008229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089610008229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T23:47:14Z","timestamp":1760831234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089610008229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":28,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0968089610008229"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2010.09.007","relation":{},"ISSN":["0968-0896"],"issn-type":[{"type":"print","value":"0968-0896"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2010.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}