{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:29:48Z","timestamp":1792783788032,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"National Plan of Science, Technology and Innovation","award":["11-MED1874-02"],"award-info":[{"award-number":["11-MED1874-02"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.bmc.2014.08.015","type":"journal-article","created":{"date-parts":[[2014,8,21]],"date-time":"2014-08-21T06:32:19Z","timestamp":1408602739000},"page":"5133-5140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Quinazoline\u2013sulfonamides with potent inhibitory activity against the \u03b1-carbonic anhydrase from Vibrio cholerae"],"prefix":"10.1016","volume":"22","author":[{"given":"Ahmed M.","family":"Alafeefy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Ceruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul-Malek S.","family":"Al-Tamimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Del Prete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemente","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2014.08.015_b0005","first-page":"4111","author":"Basel","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bmc.2014.08.015_b0010","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S1473-3099(07)70138-X","volume":"7","author":"Zuckerman","year":"2007","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.bmc.2014.08.015_b0015","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1128\/IAI.01094-07","volume":"75","author":"Matson","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bmc.2014.08.015_b0020","first-page":"75","volume":"2007","author":"Chatterjee","year":"1946","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bmc.2014.08.015_b0025","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1128\/IAI.01377-13","volume":"82","author":"Fan","year":"2014","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bmc.2014.08.015_b0030","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2958.2000.02111.x","volume":"38","author":"Yu","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bmc.2014.08.015_h0035","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmc.2014.08.015_h0040","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1517\/17460441.2013.795145","volume":"8","author":"De Simone","year":"2013","journal-title":"Expert Opin. Drug Discov."},{"key":"10.1016\/j.bmc.2014.08.015_h0045","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","volume":"20","author":"Supuran","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2014.08.015_h0050","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3109\/14756366.2012.700640","volume":"28","author":"Harju","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0055","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3109\/14756366.2012.672983","volume":"27","author":"Supuran","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0060","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","volume":"112","author":"Alterio","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmc.2014.08.015_h0065","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1517\/13543776.2013.778246","volume":"23","author":"Supuran","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0070","doi-asserted-by":"crossref","first-page":"7210","DOI":"10.1016\/j.bmc.2013.08.033","volume":"21","author":"Pinard","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0075","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3109\/14756366.2013.761876","volume":"28","author":"Supuran","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0080","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3109\/14756366.2013.787422","volume":"29","author":"Capasso","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0085","doi-asserted-by":"crossref","first-page":"10742","DOI":"10.1021\/jm301611m","volume":"55","author":"Del Prete","year":"2012","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0090","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/14756366.2012.747197","volume":"29","author":"De Del Prete","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0095","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3109\/14756366.2011.629198","volume":"27","author":"\u00c7avdar","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0100","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/1475636031000071817","volume":"18","author":"Chohan","year":"2003","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0105","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3109\/14756366.2011.597749","volume":"27","author":"Fabrizi","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0110","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/14756366.2011.643303","volume":"28","author":"Ekinci","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0115","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1517\/13543776.2012.649006","volume":"22","author":"Carta","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0120","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1517\/13543776.2013.794788","volume":"23","author":"Masini","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0125","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/j.bmcl.2013.01.084","volume":"23","author":"Vullo","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2014.08.015_h0130","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3109\/14756366.2012.658788","volume":"28","author":"Alp","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0135","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1517\/13543776.2012.698264","volume":"22","author":"Carta","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0140","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1517\/13543776.2013.778246","volume":"23","author":"Supuran","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0145","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3109\/14756366.2011.649269","volume":"28","author":"Supuran","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0150","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1080\/1475636021000006261","volume":"17","author":"Chohan","year":"2002","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_b0060","first-page":"63","volume":"12","author":"Al-Omar","year":"2004","journal-title":"Saudi Pharm. J."},{"key":"10.1016\/j.bmc.2014.08.015_b0065","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1002\/jhet.5570310637","volume":"31","author":"Del Giudice","year":"1994","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_b0070","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/cmdc.200900043","volume":"4","author":"Casta\u00f1o","year":"2009","journal-title":"ChemMedChem"},{"key":"10.1016\/j.bmc.2014.08.015_b0075","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1016\/j.bmc.2013.01.067","volume":"21","author":"S\u00e1nchez","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_b0080","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s11164-011-0327-6","volume":"38","author":"Gong-Bao","year":"2012","journal-title":"Res. Chem. Intermed."},{"key":"10.1016\/j.bmc.2014.08.015_b0085","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah","year":"1971","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0185","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0223-5234(98)80059-7","volume":"33","author":"Supuran","year":"1998","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0190","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1517\/13543776.2013.780598","volume":"23","author":"Carta","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0195","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1517\/13543776.2013.790957","volume":"23","author":"Scozzafava","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2014.08.015_h0200","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3109\/14756366.2012.736979","volume":"28","author":"Gieling","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0205","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1021\/jm061320h","volume":"50","author":"Wilkinson","year":"2007","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0210","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3109\/14756366.2011.650692","volume":"28","author":"Bonneau","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0215","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3109\/14756366.2011.649268","volume":"28","author":"Maresca","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0220","doi-asserted-by":"crossref","first-page":"818","DOI":"10.3109\/14756366.2011.617745","volume":"27","author":"Alp","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0225","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2174\/092986712799034824","volume":"19","author":"Supuran","year":"2012","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0230","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3109\/14756366.2011.637202","volume":"27","author":"Kazanc\u0131o\u011flu","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0235","doi-asserted-by":"crossref","first-page":"886","DOI":"10.3109\/14756366.2011.638921","volume":"27","author":"Liu","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0240","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3109\/14756366.2011.645539","volume":"28","author":"Maresca","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2014.08.015_h0245","doi-asserted-by":"crossref","first-page":"412","DOI":"10.3109\/14756366.2011.651464","volume":"28","author":"Koz","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."}],"container-title":["Bioorganic &amp; Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089614006026?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089614006026?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:24:56Z","timestamp":1760833496000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089614006026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":49,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S0968089614006026"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2014.08.015","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quinazoline\u2013sulfonamides with potent inhibitory activity against the \u03b1-carbonic anhydrase from Vibrio cholerae","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2014.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}