{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:18:32Z","timestamp":1791263912040,"version":"4.1.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Marie Curie ITN"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.bmc.2015.02.023","type":"journal-article","created":{"date-parts":[[2015,2,20]],"date-time":"2015-02-20T21:15:55Z","timestamp":1424466955000},"page":"1430-1436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action"],"prefix":"10.1016","volume":"23","author":[{"given":"Aiga","family":"Grandane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammet","family":"Tanc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raivis","family":"\u017dalubovskis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2015.02.023_b0005","doi-asserted-by":"crossref","first-page":"5541","DOI":"10.1016\/j.tet.2012.04.080","volume":"68","author":"Grandane","year":"2012","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmc.2015.02.023_h0010","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.bmc.2014.01.043","volume":"22","author":"Grandane","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0015","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1021\/jm301625s","volume":"56","author":"Tars","year":"2013","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0020","doi-asserted-by":"crossref","first-page":"4502","DOI":"10.1016\/j.bmc.2013.05.032","volume":"21","author":"Tanc","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0025","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.bmcl.2014.01.076","volume":"24","author":"Grandane","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0030","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1039\/C4OB02155J","volume":"13","author":"Tanc","year":"2015","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0035","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/ja809683v","volume":"131","author":"Maresca","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmc.2015.02.023_h0040","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1021\/jm901287j","volume":"53","author":"Maresca","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0045","doi-asserted-by":"crossref","first-page":"7255","DOI":"10.1016\/j.bmcl.2010.10.094","volume":"20","author":"Maresca","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0050","doi-asserted-by":"crossref","first-page":"8271","DOI":"10.1021\/jm200983e","volume":"54","author":"Touisni","year":"2011","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0055","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3109\/14756366.2011.650692","volume":"28","author":"Bonneau","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0060","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.bmcl.2011.11.018","volume":"22","author":"Carta","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0065","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1016\/j.bmcl.2012.01.129","volume":"22","author":"Carta","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0070","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1016\/j.bmc.2012.02.014","volume":"20","author":"Carta","year":"2012","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0075","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/j.bmc.2012.07.021","volume":"21","author":"Davis","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0080","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","volume":"112","author":"Alterio","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmc.2015.02.023_h0085","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmc.2015.02.023_h0090","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nrd3554","volume":"10","author":"Neri","year":"2011","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmc.2015.02.023_h0095","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1016\/j.bmc.2012.08.019","volume":"21","author":"Aggarwal","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0100","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1517\/13543776.2012.707646","volume":"22","author":"Aggarwal","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0105","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3109\/14756366.2012.672983","volume":"27","author":"Supuran","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0110","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1517\/13543776.2013.778246","volume":"23","author":"Supuran","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0115","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.bmc.2013.02.026","volume":"21","author":"Supuran","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0120","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3109\/14756366.2013.761876","volume":"28","author":"Supuran","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0125","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2174\/1568016043477305","volume":"2","author":"Supuran","year":"2004","journal-title":"Curr. Med. Chem.\u2014Cardiovasc. Hematol. Agents"},{"key":"10.1016\/j.bmc.2015.02.023_h0130","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1517\/13543776.2013.777042","volume":"23","author":"Supuran","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0135","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1046\/j.1365-201X.2002.01010.x","volume":"176","author":"Ridderstr\u00e5le","year":"2002","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.bmc.2015.02.023_h0140","doi-asserted-by":"crossref","first-page":"5529","DOI":"10.1021\/jm3004587","volume":"55","author":"Durdagi","year":"2012","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0145","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1517\/17460441.2013.795145","volume":"8","author":"De Simone","year":"2013","journal-title":"Expert Opin. Drug Discov."},{"key":"10.1016\/j.bmc.2015.02.023_h0150","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1517\/13543776.2013.794788","volume":"23","author":"Masini","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0155","first-page":"31","volume":"1001","author":"Briganti","year":"1996","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0160","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.bmc.2012.06.053","volume":"21","author":"Arechederra","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0165","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1517\/13543776.2013.790957","volume":"23","author":"Scozzafava","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0170","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3109\/14756366.2012.700640","volume":"28","author":"Harju","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0175","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3109\/14756366.2013.787422","volume":"29","author":"Capasso","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0180","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1517\/13543776.2013.780598","volume":"23","author":"Carta","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0185","doi-asserted-by":"crossref","first-page":"661","DOI":"10.2174\/138161208783877956","volume":"14","author":"Thiry","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmc.2015.02.023_h0190","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2174\/156802607780636726","volume":"7","author":"Thiry","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0195","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1517\/13543776.2013.782394","volume":"23","author":"Aggarwal","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0200","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3109\/14756366.2011.597749","volume":"27","author":"Fabrizi","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0205","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1517\/13543776.2012.649006","volume":"22","author":"Carta","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0210","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0960-894X(00)00722-8","volume":"11","author":"Scozzafava","year":"2001","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0215","doi-asserted-by":"crossref","first-page":"4231","DOI":"10.1002\/anie.201310709","volume":"53","author":"Krall","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmc.2015.02.023_h0220","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1517\/13543776.2013.798648","volume":"23","author":"Monti","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmc.2015.02.023_h0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14756360902784425","volume":"24","author":"Ebbesen","year":"2009","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0230","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bmcl.2003.09.064","volume":"14","author":"Abbate","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2015.02.023_h0235","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/1475636031000071817","volume":"18","author":"Chohan","year":"2003","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0240","series-title":"Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications","first-page":"291","article-title":"Carbonic Anhydrase Inhibitors Drug Design","author":"Supuran","year":"2014"},{"key":"10.1016\/j.bmc.2015.02.023_h0245","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0223-5234(99)80039-7","volume":"34","author":"Supuran","year":"1999","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0250","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/14756360310001624948","volume":"20","author":"Chohan","year":"2005","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0255","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1080\/1475636021000006261","volume":"17","author":"Chohan","year":"2002","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_b0085","unstructured":"See more at ClinicalTrails.gov: Safety Study of SLC-0111 in Subjects with Advanced Solid Tumours\u2014Full Text View\u2014ClinicalTrials_gov.mht."},{"key":"10.1016\/j.bmc.2015.02.023_h0265","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1021\/jm101541x","volume":"54","author":"Pacchiano","year":"2011","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0270","doi-asserted-by":"crossref","first-page":"84","DOI":"10.18632\/oncotarget.422","volume":"3","author":"McDonald","year":"2012","journal-title":"Oncotarget"},{"key":"10.1016\/j.bmc.2015.02.023_h0275","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1021\/jm0512600","volume":"49","author":"Nishimori","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0280","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1021\/cr00039a007","volume":"95","author":"Miyoura","year":"1995","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmc.2015.02.023_h0285","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1080\/00397919908086198","volume":"29","author":"Cho","year":"2009","journal-title":"Synth. Commun."},{"key":"10.1016\/j.bmc.2015.02.023_b0100","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah","year":"1971","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0295","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3109\/14756366.2011.641015","volume":"28","author":"Maresca","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0300","doi-asserted-by":"crossref","first-page":"845","DOI":"10.3109\/14756366.2011.621122","volume":"27","author":"Ekinci","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0305","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/14756366.2011.643303","volume":"28","author":"Ekinci","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0310","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3109\/14756366.2012.658788","volume":"28","author":"Alp","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0315","doi-asserted-by":"crossref","first-page":"886","DOI":"10.3109\/14756366.2011.638921","volume":"27","author":"Liu","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0320","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/14756366.2011.640633","volume":"28","author":"Demirda\u011f","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0325","doi-asserted-by":"crossref","first-page":"25475","DOI":"10.1074\/jbc.M804726200","volume":"283","author":"Moya","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0330","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3109\/14756366.2011.649268","volume":"28","author":"Maresca","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0335","doi-asserted-by":"crossref","first-page":"412","DOI":"10.3109\/14756366.2011.651464","volume":"28","author":"Koz","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0340","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3109\/14756366.2011.649269","volume":"28","author":"Supuran","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0345","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3109\/14756366.2012.761608","volume":"29","author":"Migliardini","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_b0120","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3109\/14756366.2012.736979","volume":"28","author":"Gieling","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0355","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/j.bmc.2012.05.037","volume":"21","author":"Compain","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0360","doi-asserted-by":"crossref","first-page":"6015","DOI":"10.1039\/c3cc40858b","author":"M\u00e9tayer","year":"2013","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bmc.2015.02.023_h0365","doi-asserted-by":"crossref","first-page":"7540","DOI":"10.1039\/c3ob41538d","volume":"11","author":"M\u00e9tayer","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bmc.2015.02.023_h0370","series-title":"Targeting Carbonic Anhydrases","first-page":"53","article-title":"Next-generation Secondary\/Tertiary Sulfonamide Carbonic Anhydrase Inhibitors","author":"Thibaudeau","year":"2014"}],"container-title":["Bioorganic &amp; Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089615001170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089615001170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:29:54Z","timestamp":1760833794000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089615001170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":74,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0968089615001170"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2015.02.023","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2015.02.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}