{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T21:06:30Z","timestamp":1768424790252,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB 630"],"award-info":[{"award-number":["SFB 630"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["A1"],"award-info":[{"award-number":["A1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.bmc.2016.06.003","type":"journal-article","created":{"date-parts":[[2016,6,4]],"date-time":"2016-06-04T19:06:20Z","timestamp":1465067180000},"page":"3636-3642","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Bistacrine derivatives as new potent antimalarials"],"prefix":"10.1016","volume":"24","author":[{"given":"Ines","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Pradel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludmilla","family":"Sologub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Golzmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Che J.","family":"Ngwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Kucharski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Schirmeister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0364-7278","authenticated-orcid":false,"given":"Ulrike","family":"Holzgrabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2016.06.003_b0005","unstructured":"World Health Organization. Malaria Fact Sheet 2016. Available from: <http:\/\/www.who.int\/mediacentre\/factsheets\/fs094\/en\/> (accessed 12.02.2016)."},{"key":"10.1016\/j.bmc.2016.06.003_b0010","unstructured":"World Health Organization. World Malaria Report 2015. Available from: <http:\/\/apps.who.int\/iris\/bitstream\/10665\/200018\/1\/9789241565158_eng.pdf?ua=1> (accessed 12.02.2016)."},{"key":"10.1016\/j.bmc.2016.06.003_b0015","doi-asserted-by":"crossref","first-page":"3704","DOI":"10.1021\/jm0491039","volume":"48","author":"Nallan","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0020","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.cbpa.2007.05.038","volume":"11","author":"Gelb","year":"2007","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.bmc.2016.06.003_b0025","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1016\/S0968-0896(01)00032-3","volume":"9","author":"Homann","year":"2001","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0030","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/355167a0","volume":"355","author":"Slater","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.bmc.2016.06.003_b0035","unstructured":"Lee, T. B. K., 1992."},{"key":"10.1016\/j.bmc.2016.06.003_b0040","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1021\/jm010308g","volume":"45","author":"Hu","year":"2002","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0045","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4269\/ajtmh.1993.48.205","volume":"48","author":"Makler","year":"1993","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.bmc.2016.06.003_b0050","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0022-1759(94)90396-4","volume":"170","author":"Ahmed","year":"1994","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.bmc.2016.06.003_b0055","doi-asserted-by":"crossref","first-page":"11865","DOI":"10.1073\/pnas.93.21.11865","volume":"93","author":"Sullivan","year":"1996","journal-title":"PNAS"},{"key":"10.1016\/j.bmc.2016.06.003_b0060","doi-asserted-by":"crossref","first-page":"14961","DOI":"10.1074\/jbc.272.23.14961","volume":"272","author":"Francis","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0065","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.1073\/pnas.1218412110","volume":"110","author":"Chugh","year":"2013","journal-title":"PNAS"},{"key":"10.1016\/j.bmc.2016.06.003_b0070","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ab.2004.11.022","volume":"338","author":"Ncokazi","year":"2005","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2016.06.003_b0075","doi-asserted-by":"crossref","first-page":"29000","DOI":"10.1074\/jbc.M004459200","volume":"275","author":"Shenai","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1146\/annurev.micro.51.1.97","volume":"51","author":"Francis","year":"1997","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.bmc.2016.06.003_b0085","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/cmdc.201000370","volume":"6","author":"Buchold","year":"2011","journal-title":"ChemMedChem"},{"key":"10.1016\/j.bmc.2016.06.003_b0090","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1128\/AAC.47.1.154-160.2003","volume":"47","author":"Shenai","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bmc.2016.06.003_b0095","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1021\/jm701141u","volume":"51","author":"Ettari","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0100","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.ejmech.2015.06.052","volume":"101","author":"Mahapatra","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0105","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/S0968-0896(03)00117-2","volume":"11","author":"Batra","year":"2003","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0110","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1021\/jm00193a020","volume":"22","author":"Klayman","year":"1979","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0115","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1021\/bi00534a031","volume":"21","author":"Tian","year":"1982","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmc.2016.06.003_b0120","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1021\/jm990971t","volume":"43","author":"Recanatini","year":"2000","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0125","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/jhet.5570430332","volume":"43","author":"Li","year":"2006","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmc.2016.06.003_b0130","unstructured":"Skotnicki, J. S.; Gilman, S.C., 1990."},{"key":"10.1016\/j.bmc.2016.06.003_b0135","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.3390\/molecules18022397","volume":"18","author":"Spilovska","year":"2013","journal-title":"Molecules"},{"key":"10.1016\/j.bmc.2016.06.003_b0140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1211\/0022357011775046","volume":"53","author":"Hu","year":"2001","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.bmc.2016.06.003_b0145","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1016\/j.bmcl.2006.07.025","volume":"16","author":"Tripathi","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmc.2016.06.003_b0150","doi-asserted-by":"crossref","first-page":"8424","DOI":"10.1021\/jo061349t","volume":"71","author":"Kayser","year":"2006","journal-title":"J. Org. Chem."}],"container-title":["Bioorganic &amp; Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089616304205?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089616304205?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:45:07Z","timestamp":1760834707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089616304205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":30,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0968089616304205"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2016.06.003","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bistacrine derivatives as new potent antimalarials","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2016.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}