{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:13:33Z","timestamp":1790244813206,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"22","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.bmc.2016.08.023","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T06:18:06Z","timestamp":1472797086000},"page":"5685-5692","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors"],"prefix":"10.1016","volume":"24","author":[{"given":"Marion","family":"Verdoni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermine","family":"Roudaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"De Pomyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Gigmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Bertin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Luis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abd Haq","family":"Bengeloune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamel","family":"Mabrouk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2016.08.023_b0005","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1096\/fj.06-6649rev","volume":"21","author":"Costin","year":"2007","journal-title":"FASEB J. Rev."},{"key":"10.1016\/j.bmc.2016.08.023_b0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.mrfmmm.2004.11.016","volume":"571","author":"Agar","year":"2005","journal-title":"Mutat. Res."},{"key":"10.1016\/j.bmc.2016.08.023_b0015","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1365-4632.2012.05560.x","volume":"51","author":"Kombat\u00e9","year":"2012","journal-title":"Int. J. Dermatol."},{"key":"10.1016\/j.bmc.2016.08.023_b0020","doi-asserted-by":"crossref","first-page":"17993","DOI":"10.1016\/S0021-9258(17)32408-0","volume":"269","author":"Jimenez-Cervantes","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2016.08.023_b0025","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0923-1811(96)00575-0","volume":"14","author":"Maeda","year":"1997","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.bmc.2016.08.023_b0030","doi-asserted-by":"crossref","first-page":"31801","DOI":"10.1074\/jbc.273.48.31801","volume":"273","author":"Kobayashi","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmc.2016.08.023_b0035","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0006-2952(98)00340-2","volume":"57","author":"Curto","year":"1999","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bmc.2016.08.023_b0040","first-page":"748","volume":"21","author":"Kiskin","year":"1989","journal-title":"Neirofiziologiya"},{"key":"10.1016\/j.bmc.2016.08.023_b0045","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1134\/S1068162009060120","volume":"35","author":"Formanovsky","year":"2009","journal-title":"Russ. J. Bioorg. Chem."},{"key":"10.1016\/j.bmc.2016.08.023_b0050","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1002\/anie.200805426","volume":"48","author":"Nelson","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmc.2016.08.023_b0055","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1600-0749.2006.00334.x","volume":"19","author":"Solano","year":"2006","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.bmc.2016.08.023_b0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0014-5793(93)81533-6","volume":"324","author":"Raditsch","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmc.2016.08.023_b0065","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1600-0749.1999.tb00751.x","volume":"12","author":"Sugumuran","year":"1999","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.bmc.2016.08.023_b0070","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ijbiomac.2013.02.019","volume":"57","author":"Chai","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.bmc.2016.08.023_b0075","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1034\/j.1600-0749.2000.130308.x","volume":"13","author":"Franchi","year":"2000","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.bmc.2016.08.023_b0080","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0003-2697(86)90327-1","volume":"159","author":"Siegrist","year":"1986","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2016.08.023_b0085","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.3390\/ma5091661","volume":"5","author":"Chang","year":"2012","journal-title":"Materials"},{"key":"10.1016\/j.bmc.2016.08.023_b0090","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1039\/C3CC49389J","author":"Trimaille","year":"2014","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bmc.2016.08.023_b0095","first-page":"47","volume":"30","author":"Mojica","year":"2005","journal-title":"Cit Philipp. J. Crop Sci."},{"key":"10.1016\/j.bmc.2016.08.023_b0100","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0003-2697(88)90639-2","volume":"170","author":"Wakamatsu","year":"1988","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bmc.2016.08.023_b0105","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1042\/bj3540131","volume":"354","author":"Olivares","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmc.2016.08.023_b0110","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1432-1033.1991.tb16018.x","volume":"198","author":"Winder","year":"1991","journal-title":"Eur. J. Biochem"},{"key":"10.1016\/j.bmc.2016.08.023_b0115","unstructured":"Mabrouk, K.; Verdoni, M.; De Pomyers, H.; Luis, J.; Bengeloune, A.; Bertin, D.; Gigmes, D. Use of Spider venoms for skin Withening\/depigmenting and composition comprising spider venoms derivatives, (European Patent: EP 12006270.8 & International Patent: WO2014\/037111\/A2)."}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089616306307?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089616306307?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:43:05Z","timestamp":1760834585000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089616306307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":23,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0968089616306307"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2016.08.023","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2016.08.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}