{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T07:22:38Z","timestamp":1775373758352,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009950","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2012R1A1A2006613"],"award-info":[{"award-number":["2012R1A1A2006613"]}],"id":[{"id":"10.13039\/100009950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010079","name":"Kortney Rose Foundation","doi-asserted-by":"publisher","award":["2017R1A2A2A05001227"],"award-info":[{"award-number":["2017R1A2A2A05001227"]}],"id":[{"id":"10.13039\/100010079","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003716","name":"Korea Basic Science Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003716","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.bmc.2017.07.046","type":"journal-article","created":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T15:30:37Z","timestamp":1501169437000},"page":"5278-5289","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Triple reuptake inhibitors: Design, synthesis and structure\u2013activity relationship of benzylpiperidine\u2013tetrazoles"],"prefix":"10.1016","volume":"25","author":[{"given":"Suresh","family":"Paudel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Min","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srijan","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daulat Bikram","family":"Khadka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goo","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyeong-Man","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Hoon","family":"Cheon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2017.07.046_b0005","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1146\/annurev.neuro.28.061604.135722","volume":"30","author":"Schultz","year":"2007","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.bmc.2017.07.046_b0010","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/sj.mp.4000728","volume":"5","author":"Iversen","year":"2000","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bmc.2017.07.046_b0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrn1008","volume":"4","author":"Torres","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bmc.2017.07.046_b0020","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1124\/pr.108.000869","volume":"63","author":"Kristensen","year":"2011","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.bmc.2017.07.046_b0025","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1517\/13543776.2014.859676","volume":"24","author":"Liming","year":"2014","journal-title":"Expert. Opin. Ther. Patents"},{"key":"10.1016\/j.bmc.2017.07.046_b0030","first-page":"235","volume":"6","author":"Grouleff","year":"2015","journal-title":"Front. Pharmcol."},{"key":"10.1016\/j.bmc.2017.07.046_b0035","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1039\/b903035m","volume":"25","author":"Andersen","year":"2009","journal-title":"Chem Commun"},{"key":"10.1016\/j.bmc.2017.07.046_b0040","series-title":"Abnormal Psychology: An Integrative Approach","author":"Barlow","year":"2009"},{"key":"10.1016\/j.bmc.2017.07.046_b0045","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/ddr.20013","volume":"65","author":"Walter","year":"2005","journal-title":"Drug Dev Res"},{"key":"10.1016\/j.bmc.2017.07.046_b0050","first-page":"13","volume":"42","author":"Liu","year":"2007","journal-title":"Annu Rep Med Chem"},{"key":"10.1016\/j.bmc.2017.07.046_b0055","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1517\/13543784.2011.594039","volume":"20","author":"Prins","year":"2011","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.bmc.2017.07.046_b0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/da.20181","volume":"23","author":"Papakostas","year":"2006","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.bmc.2017.07.046_b0065","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.pharmthera.2008.10.004","volume":"121","author":"Daws","year":"2009","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.bmc.2017.07.046_b0070","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2174\/157015908787386104","volume":"6","author":"Costagliola","year":"2008","journal-title":"Curr Neuropharmacol"},{"key":"10.1016\/j.bmc.2017.07.046_b0075","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0278-5846(02)00338-X","volume":"27","author":"Vaswani","year":"2003","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.bmc.2017.07.046_b0080","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.euroneuro.2015.01.005","volume":"25","author":"Jin","year":"2015","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.bmc.2017.07.046_b0085","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1517\/13543784.16.9.1365","volume":"16","author":"Chen","year":"2007","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.bmc.2017.07.046_b0090","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.nurt.2008.10.039","volume":"13","author":"Millan","year":"2009","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.bmc.2017.07.046_b0095","first-page":"50","volume":"15","author":"Liang","year":"2008","journal-title":"Prim Psychiatry"},{"key":"10.1016\/j.bmc.2017.07.046_b0100","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1016\/j.lfs.2003.06.007","volume":"73","author":"Skolnick","year":"2003","journal-title":"Life Sci"},{"key":"10.1016\/j.bmc.2017.07.046_b0105","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1527-3458.2006.00123.x","volume":"12","author":"Skolnick","year":"2006","journal-title":"CNS Drug Rev"},{"key":"10.1016\/j.bmc.2017.07.046_b0110","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0014-2999(03)01310-4","volume":"461","author":"Skolnick","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.bmc.2017.07.046_b0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1517\/13543776.2014.859676","volume":"24","author":"Shao","year":"2014","journal-title":"Expert Opin Ther Patents"},{"key":"10.1016\/j.bmc.2017.07.046_b0120","first-page":"12","author":"Silvestrini","year":"1989","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.bmc.2017.07.046_b0125","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1016\/j.bmc.2017.02.051","volume":"25","author":"Paudel","year":"2017","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2017.07.046_b0130","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1016\/j.bmc.2016.09.005","volume":"24","author":"Paudel","year":"2016","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2017.07.046_b0135","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.bmc.2016.03.044","volume":"24","author":"Paudel","year":"2016","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2017.07.046_b0140","doi-asserted-by":"crossref","first-page":"6418","DOI":"10.1016\/j.bmc.2015.08.022","volume":"23","author":"Paudel","year":"2015","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2017.07.046_b0145","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/nature17629","volume":"532","author":"Coleman","year":"2016","journal-title":"Nature"}],"container-title":["Bioorganic & Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089617311951?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089617311951?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T00:51:51Z","timestamp":1760835111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089617311951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":29,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0968089617311951"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2017.07.046","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Triple reuptake inhibitors: Design, synthesis and structure\u2013activity relationship of benzylpiperidine\u2013tetrazoles","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2017.07.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}