{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:34:36Z","timestamp":1793122476636,"version":"4.5.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.bmc.2021.116184","type":"journal-article","created":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T04:47:14Z","timestamp":1619844434000},"page":"116184","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Synthesis of osthol-based botanical fungicides and their antifungal application in crop protection"],"prefix":"10.1016","volume":"40","author":[{"given":"Yuying","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiabao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhouyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9550-6885","authenticated-orcid":false,"given":"Shan","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmc.2021.116184_b0005","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1111\/j.1364-3703.2011.00783.x","volume":"13","author":"Dean","year":"2012","journal-title":"Mol Plant Pathol"},{"key":"10.1016\/j.bmc.2021.116184_b0010","series-title":"Plant pathogens and disease: general introduction","author":"Agrios","year":"2009"},{"key":"10.1016\/j.bmc.2021.116184_b0015","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.9734\/BMRJ\/2014\/11074","volume":"4","author":"El Hussein","year":"2014","journal-title":"Br Microbiol Res J"},{"key":"10.1016\/j.bmc.2021.116184_b0020","series-title":"The Value of Plant Disease Early-Warning Systems: A Case Study of USDA\u2019s Soybean Rust Coordinated Framework","author":"Roberts","year":"2016"},{"key":"10.1016\/j.bmc.2021.116184_b0025","series-title":"Crop losses due to diseases and their implications for global food production losses and food security","author":"Savary","year":"2012"},{"key":"10.1016\/j.bmc.2021.116184_b0030","doi-asserted-by":"crossref","first-page":"701","DOI":"10.3390\/toxins11120701","volume":"11","author":"Sarrocco","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.bmc.2021.116184_b0035","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1080\/15569540802432308","volume":"27","author":"Reddy","year":"2008","journal-title":"Toxin Reviews"},{"key":"10.1016\/j.bmc.2021.116184_b0040","first-page":"1","author":"Gonzalez-Fernandez","year":"2010","journal-title":"Biotechnol"},{"key":"10.1016\/j.bmc.2021.116184_b0045","series-title":"Natural fungicides obtained from plants, fungicides for plant and animal diseases","year":"2012"},{"key":"10.1016\/j.bmc.2021.116184_b0050","doi-asserted-by":"crossref","first-page":"205","DOI":"10.6090\/jarq.40.205","volume":"40","author":"Ishii","year":"2006","journal-title":"Jarq-Japan Agric Res Q"},{"key":"10.1016\/j.bmc.2021.116184_b0055","doi-asserted-by":"crossref","first-page":"115778","DOI":"10.1016\/j.bmc.2020.115778","volume":"28","author":"Wang","year":"2020","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2021.116184_b0060","doi-asserted-by":"crossref","first-page":"120","DOI":"10.21010\/ajtcam.v14i4.14","volume":"14","author":"Shuping","year":"2017","journal-title":"AJTCAM"},{"key":"10.1016\/j.bmc.2021.116184_b0065","first-page":"33","volume":"4","author":"Nega","year":"2014","journal-title":"J Biol Agric Healthc"},{"key":"10.1016\/j.bmc.2021.116184_b0070","first-page":"71","volume":"3","author":"Patel","year":"2014","journal-title":"Int J Curr Microbiol App Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0075","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cropro.2014.05.012","volume":"64","author":"Sivakumar","year":"2014","journal-title":"Crop Prot"},{"key":"10.1016\/j.bmc.2021.116184_b0080","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/ps.4029","volume":"71","author":"Price","year":"2015","journal-title":"Pest Manag Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0085","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1080\/10286020902942350","volume":"11","author":"Arif","year":"2009","journal-title":"J Asian Nat Prod Res"},{"key":"10.1016\/j.bmc.2021.116184_b0090","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cropro.2018.04.003","volume":"110","author":"Borges","year":"2018","journal-title":"Crop Prot"},{"issue":"8","key":"10.1016\/j.bmc.2021.116184_b0095","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3390\/agriculture8080125","volume":"8","author":"Ikechukwu Obi","year":"2018","journal-title":"Agriculture-Basel"},{"key":"10.1016\/j.bmc.2021.116184_b0100","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1755-0238.2009.0067.x","volume":"16","author":"Jacometti","year":"2010","journal-title":"Aust J Grape Wine Res"},{"key":"10.1016\/j.bmc.2021.116184_b0105","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.tplants.2015.01.004","volume":"20","author":"Kanchiswamy","year":"2015","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5423\/PPJ.RW.05.2012.0072","volume":"29","author":"Yoon","year":"2013","journal-title":"Plant Pathol J"},{"key":"10.1016\/j.bmc.2021.116184_b0115","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1146\/annurev-phyto-102313-050158","volume":"52","author":"van den Bosch","year":"2014","journal-title":"Annu Rev Phytopathol"},{"key":"10.1016\/j.bmc.2021.116184_b0120","doi-asserted-by":"crossref","first-page":"115048","DOI":"10.1016\/j.bmc.2019.115048","volume":"27","author":"Ahmed","year":"2019","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmc.2021.116184_b0125","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jep.2006.04.003","volume":"106","author":"Cos","year":"2006","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.bmc.2021.116184_b0130","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.chroma.2004.01.058","volume":"1033","author":"Wei","year":"2004","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.bmc.2021.116184_b0135","first-page":"142","author":"Liang","year":"2019","journal-title":"Ind Crop Prod"},{"key":"10.1016\/j.bmc.2021.116184_b0140","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jep.2018.10.040","volume":"231","author":"Ma","year":"2019","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.bmc.2021.116184_b0145","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1055\/s-2008-1034281","volume":"74","author":"Sharma","year":"2008","journal-title":"Planta Med"},{"key":"10.1016\/j.bmc.2021.116184_b0150","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00436-010-2058-9","volume":"108","author":"Wang","year":"2011","journal-title":"Parasitol Res"},{"issue":"1","key":"10.1016\/j.bmc.2021.116184_b0155","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.3390\/ijms14011197","volume":"14","author":"Wang","year":"2013","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0160","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.chroma.2008.04.070","volume":"1200","author":"Zhou","year":"2008","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.bmc.2021.116184_b0165","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00284-016-1191-9","volume":"74","author":"Wang","year":"2017","journal-title":"Curr Microbiol"},{"key":"10.1016\/j.bmc.2021.116184_b0170","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/ps.4422","volume":"73","author":"Song","year":"2017","journal-title":"Pest Manag Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0175","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.3390\/i8091001","volume":"8","author":"Shi","year":"2007","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.bmc.2021.116184_b0180","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1021\/jf104772x","volume":"59","author":"Vogl","year":"2011","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.bmc.2021.116184_b0185","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1080\/10286020.2010.495331","volume":"12","author":"Wang","year":"2010","journal-title":"J Asian Nat Prod Res"},{"key":"10.1016\/j.bmc.2021.116184_b0190","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejmech.2016.08.012","volume":"124","author":"Zhang","year":"2016","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmc.2021.116184_b0195","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s11030-019-09920-z","volume":"23","author":"Zhang","year":"2019","journal-title":"Mol Divers"},{"key":"10.1016\/j.bmc.2021.116184_b0200","first-page":"107","volume":"42","author":"Yang","year":"2011","journal-title":"J China Pharm Univ"},{"key":"10.1016\/j.bmc.2021.116184_b0205","doi-asserted-by":"crossref","first-page":"4363","DOI":"10.1016\/S0040-4020(03)00624-0","volume":"59","author":"Gillmore","year":"2003","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmc.2021.116184_b0210","unstructured":"Desal RC, Pingali H. Oxinimo derivatives for the treatment of dyslipidemia. EP3083587."},{"key":"10.1016\/j.bmc.2021.116184_b0215","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1016\/j.bmcl.2018.04.034","volume":"28","author":"Zhou","year":"2018","journal-title":"Bioorg Med Chem Lett"}],"container-title":["Bioorganic &amp; Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089621001929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968089621001929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T01:14:07Z","timestamp":1760836447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968089621001929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":43,"alternative-id":["S0968089621001929"],"URL":"https:\/\/doi.org\/10.1016\/j.bmc.2021.116184","relation":{},"ISSN":["0968-0896"],"issn-type":[{"value":"0968-0896","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of osthol-based botanical fungicides and their antifungal application in crop protection","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmc.2021.116184","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116184"}}