{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T13:16:19Z","timestamp":1788527779746,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2004,5,1]],"date-time":"2004-05-01T00:00:00Z","timestamp":1083369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,5,1]],"date-time":"2004-05-01T00:00:00Z","timestamp":1083369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2004,5]]},"DOI":"10.1016\/j.bmcl.2004.02.075","type":"journal-article","created":{"date-parts":[[2004,3,17]],"date-time":"2004-03-17T05:36:05Z","timestamp":1079501765000},"page":"2567-2570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Discovery of a potent and selective \u03b1v\u03b23 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model"],"prefix":"10.1016","volume":"14","author":[{"given":"Seiji","family":"Iwama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Kitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiyo","family":"Fukuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayoi","family":"Honda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsue","family":"Notake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Morie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2004.02.075_BIB1_1","unstructured":"The STRESS Investigators. New Engl. J. Med. 1994, 331, 496"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB1_2","unstructured":"The BENESTENT Study Group. New Engl. J. Med. 1994, 331, 489"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB1_3","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1161\/01.CIR.0000038982.49640.70","volume":"106","author":"Babapulle","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB2_1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1055\/s-0037-1614578","volume":"81","author":"Johnson","year":"1999","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB2_2","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1517\/13543784.9.11.2555","volume":"9","author":"Gruberg","year":"2000","journal-title":"Exp. Opin. Invest. Drugs"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB3","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/362801a0","volume":"362","author":"Ross","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB4","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1055\/s-0037-1615250","volume":"80","author":"Byzova","year":"1998","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1055\/s-0037-1612971","volume":"87","author":"Sajid","year":"2002","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB6","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1126\/science.7512751","volume":"264","author":"Brooks","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB7_1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S1359-6446(00)01545-2","volume":"5","author":"Miller","year":"2000","journal-title":"Drug Discovery Today"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB7_2","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1517\/13543776.10.9.1367","volume":"10","author":"Duggan","year":"2000","journal-title":"Exp. Opin. Ther. Patents"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB7_3","first-page":"72","volume":"4","author":"H\u00f6lzemann","year":"2001","journal-title":"IDrugs"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB7_4","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1517\/13543776.12.7.1009","volume":"12","author":"Coleman","year":"2002","journal-title":"Exp. Opin. Ther. Patents"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB8_1","doi-asserted-by":"crossref","first-page":"7461","DOI":"10.1021\/ja9603721","volume":"118","author":"Haubner","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB8_2","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1002\/anie.199713741","volume":"36","author":"Haubner","year":"1997","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB9","doi-asserted-by":"crossref","first-page":"13285","DOI":"10.1016\/S0040-4020(99)00818-2","volume":"55","author":"Belfield","year":"1999","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB10","doi-asserted-by":"crossref","first-page":"7677","DOI":"10.1016\/S0040-4039(00)61537-X","volume":"34","author":"Kim","year":"1993","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB11","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/00019501-199610000-00010","volume":"7","author":"Mousa","year":"1996","journal-title":"Coron. Artery Dis."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB12_1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1055\/s-0038-1650271","volume":"75","author":"Kosugi","year":"1996","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB12_2","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1182\/blood.V93.8.2559","volume":"93","author":"Kashiwagi","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.bmcl.2004.02.075_BIB13","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1248\/cpb.41.1118","volume":"41","author":"Ishiyama","year":"1993","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.bmcl.2004.02.075_BIB14","first-page":"327","volume":"49","author":"Clowes","year":"1983","journal-title":"Lab. Invest."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X04002938?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X04002938?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T05:26:54Z","timestamp":1760765214000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X04002938"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0960894X04002938"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2004.02.075","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Discovery of a potent and selective \u03b1v\u03b23 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2004.02.075","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}