{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T13:47:33Z","timestamp":1765806453617,"version":"build-2065373602"},"reference-count":55,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.bmcl.2004.12.056","type":"journal-article","created":{"date-parts":[[2005,1,25]],"date-time":"2005-01-25T14:49:35Z","timestamp":1106664575000},"page":"923-930","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II"],"prefix":"10.1016","volume":"15","author":[{"given":"Padmakar V.","family":"Khadikar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vimukta","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sneha","family":"Karmarkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2004.12.056_bib1","unstructured":"Simon, Z.; Chiriac, A.; Holban, S.; Ciubotariu, D.; Mihalas, G. I. Minimum Steric Difference. The MTD method for QSAR Studies. Research Study Press: Letchworth, UK, 1984"},{"year":"1986","series-title":"Molecular Connectivity in Structure\u2013Activity Relationship","author":"Kier","key":"10.1016\/j.bmcl.2004.12.056_bib2"},{"year":"1987","series-title":"Quantitative Structure\u2013Chromatographic Retention Relationships","author":"Kaliszan","key":"10.1016\/j.bmcl.2004.12.056_bib3"},{"year":"1990","series-title":"Practical Applications of Quantitative Structure\u2013Activity-Relationships (QSAR) in Environmental Chemistry and Toxicology in Chemical and Environmental Science","key":"10.1016\/j.bmcl.2004.12.056_bib4"},{"year":"1991","series-title":"QSAR: Rational Approaches to the Design of Bioactive Compounds in Pharmacochemistry","key":"10.1016\/j.bmcl.2004.12.056_bib5"},{"year":"1993","series-title":"3D QSAR in Drug Design: Theory, Methods and Applications","author":"Kubinyi","key":"10.1016\/j.bmcl.2004.12.056_bib6"},{"year":"1994","series-title":"QSAR: Hansch Analysis and Related Approaches","author":"Kubinyi","key":"10.1016\/j.bmcl.2004.12.056_bib7"},{"year":"1995","series-title":"QSQR in Molecular Modeling: Concepts, Computational Tools and Biological Applications","key":"10.1016\/j.bmcl.2004.12.056_bib8"},{"year":"1996","series-title":"Exploring QSAR Fundamental and Applications in Chemistry and Biology","author":"Hansch","key":"10.1016\/j.bmcl.2004.12.056_bib9"},{"year":"1996","series-title":"Structure\u2013Property Correlations in Drug Research","key":"10.1016\/j.bmcl.2004.12.056_bib10"},{"key":"10.1016\/j.bmcl.2004.12.056_bib11","unstructured":"Diudea, M. V.; Khadikar, P. V., Molecular Topology and its Applications, Gilotia Pub: New Delhi, India, in press"},{"year":"2000","series-title":"QSAR\/QSPR Studies by Molecular Descriptors","key":"10.1016\/j.bmcl.2004.12.056_bib12"},{"year":"1998","series-title":"3D QSAR in Drug Design Ligand\u2013Protein Interaction and Molecularity","key":"10.1016\/j.bmcl.2004.12.056_bib13"},{"year":"1998","series-title":"3D QSAR in Drug Design: Recent Advances","key":"10.1016\/j.bmcl.2004.12.056_bib14"},{"year":"1998","series-title":"Comparative QSAR","key":"10.1016\/j.bmcl.2004.12.056_bib15"},{"year":"1999","series-title":"Topological Indices and Related Descriptors in QSAR and QSPR","key":"10.1016\/j.bmcl.2004.12.056_bib16"},{"year":"2000","series-title":"Molecular Descriptors in QSAR\/QSPR","author":"Karelson","key":"10.1016\/j.bmcl.2004.12.056_bib17"},{"key":"10.1016\/j.bmcl.2004.12.056_bib18","first-page":"345","volume":"66","author":"Plavsic","year":"1993","journal-title":"Croatica Chem. Acta"},{"key":"10.1016\/j.bmcl.2004.12.056_bib19_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","article-title":"Carbonic Anhydrase Inibitors","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2004.12.056_bib19_2","series-title":"Carbonic Anhydrase, its Inhibitors and Activators","first-page":"149","article-title":"QSAR Studies of Sulfonamide Carbonic Anhydrase Inhibitors","author":"Clare","year":"2004"},{"key":"10.1016\/j.bmcl.2004.12.056_bib20","first-page":"171","volume":"49","author":"Saxena","year":"1999","journal-title":"Acta Pharm."},{"key":"10.1016\/j.bmcl.2004.12.056_bib21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1556\/AMicr.48.2001.1.3","volume":"48","author":"Agrawal","year":"2001","journal-title":"Acta Microbiol. Immunol. Hung."},{"key":"10.1016\/j.bmcl.2004.12.056_bib22","doi-asserted-by":"crossref","first-page":"3287","DOI":"10.1016\/S0968-0896(01)00241-3","volume":"9","author":"Agrawal","year":"2001","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib23","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1016\/S0968-0896(02)00123-2","volume":"10","author":"Agrawal","year":"2002","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib24","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.1016\/j.bmc.2003.09.037","volume":"11","author":"Agrawal","year":"2003","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib25","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.bmc.2003.10.058","volume":"12","author":"Thakur","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib26","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.bmc.2004.01.049","volume":"12","author":"Jaiswal","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib27","doi-asserted-by":"crossref","first-page":"3283","DOI":"10.1016\/j.bmcl.2004.03.099","volume":"14","author":"Jaiswal","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2004.12.056_bib28","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.ejmech.2004.03.002","volume":"39","author":"Agrawal","year":"2004","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib29","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0960-894X(02)00954-X","volume":"13","author":"Agrawal","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"year":"1986","series-title":"Mathematical Concepts in Organic Chemistry","author":"Gutman","key":"10.1016\/j.bmcl.2004.12.056_bib30"},{"year":"1993","series-title":"Chemical Graph Theory","author":"Trinajstic","key":"10.1016\/j.bmcl.2004.12.056_bib31"},{"year":"1995","series-title":"Molecular Topology","author":"Diudea","key":"10.1016\/j.bmcl.2004.12.056_bib32"},{"volume":"Vol. II","year":"1983","author":"Trinajstic","key":"10.1016\/j.bmcl.2004.12.056_bib33"},{"year":"2000","series-title":"Handbook of Molecular Descriptors","author":"Todeschini","key":"10.1016\/j.bmcl.2004.12.056_bib34"},{"key":"10.1016\/j.bmcl.2004.12.056_bib35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1021\/ja01193a005","volume":"69","author":"Wiener","year":"1947","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2004.12.056_bib36","first-page":"9","volume":"27","author":"Gutman","year":"1994","journal-title":"Graph Theory Notes, N.Y."},{"key":"10.1016\/j.bmcl.2004.12.056_bib37","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1021\/ci00025a024","volume":"35","author":"Khadikar","year":"1975","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"10.1016\/j.bmcl.2004.12.056_bib38","first-page":"7","volume":"43","author":"Khadikar","year":"2001","journal-title":"Commun. Math. Comput. Chem. (MATCH)"},{"key":"10.1016\/j.bmcl.2004.12.056_bib39","first-page":"113","volume":"23","author":"Khadikar","year":"2000","journal-title":"Natl. Acad. Sci. Lett."},{"key":"10.1016\/j.bmcl.2004.12.056_bib40","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1021\/ci0003092","volume":"41","author":"Khadikar","year":"2001","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"10.1016\/j.bmcl.2004.12.056_bib41","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1023\/A:1010931213729","volume":"29","author":"Khadikar","year":"2001","journal-title":"J. Math. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib42","doi-asserted-by":"crossref","first-page":"6609","DOI":"10.1021\/ja00856a001","volume":"97","author":"Randic","year":"1975","journal-title":"J. Am. Chem. Soc."},{"year":"1976","series-title":"Molecular Connectivity in Chemistry and Drug Research","author":"Kier","key":"10.1016\/j.bmcl.2004.12.056_bib43"},{"key":"10.1016\/j.bmcl.2004.12.056_bib44","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1021\/cr0000067","volume":"101","author":"Hansch","year":"2001","journal-title":"Chem. Rev."},{"year":"2000","series-title":"Regression Analysis by Examples","author":"Chaterjee","key":"10.1016\/j.bmcl.2004.12.056_bib45"},{"key":"10.1016\/j.bmcl.2004.12.056_bib46","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1098\/rspb.1976.0034","volume":"193","author":"King","year":"1976","journal-title":"Proc. R. Soc. London B"},{"key":"10.1016\/j.bmcl.2004.12.056_bib47","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1021\/ci00005a004","volume":"32","author":"Balaban","year":"1992","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"10.1016\/j.bmcl.2004.12.056_bib48","first-page":"115","volume":"21","author":"Balaban","year":"1986","journal-title":"Math. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib49","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF00805842","volume":"6","author":"Pogliani","year":"1994","journal-title":"Amino Acids"},{"key":"10.1016\/j.bmcl.2004.12.056_bib50","doi-asserted-by":"crossref","first-page":"18065","DOI":"10.1021\/jp961434c","volume":"100","author":"Pogliani","year":"1996","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib51","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1016\/j.bmc.2004.02.010","volume":"12","author":"Thakur","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2004.12.056_bib52","doi-asserted-by":"crossref","first-page":"5661","DOI":"10.1016\/j.bmcl.2004.08.051","volume":"14","author":"Jaiswal","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2004.12.056_bib53","first-page":"289","volume":"66","author":"Randic","year":"1993","journal-title":"Croat. Chem. Acta"},{"key":"10.1016\/j.bmcl.2004.12.056_bib54","unstructured":"Todeschini, R., Some Observations about Pogliani Q, Quality Index; In Chimometrics Web News, Miland Chemo metrics and QSAR Research Group (File: 111C\/Windows\/Desktop\/WebNewsonChemometrics.html), 2001"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X04015185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X04015185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T05:33:08Z","timestamp":1760765588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X04015185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":55,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0960894X04015185"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2004.12.056","relation":{},"ISSN":["0960-894X"],"issn-type":[{"type":"print","value":"0960-894X"}],"subject":[],"published":{"date-parts":[[2005,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2004.12.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}