{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:09:50Z","timestamp":1791234590695,"version":"4.1.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.bmcl.2005.04.055","type":"journal-article","created":{"date-parts":[[2005,5,24]],"date-time":"2005-05-24T08:15:39Z","timestamp":1116922539000},"page":"3096-3101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":111,"title":["Carbonic anhydrase inhibitors. Inhibition of cytosolic\/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff\u2019s bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes"],"prefix":"10.1016","volume":"15","author":[{"given":"Luca","family":"Puccetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Fasolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Vullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahid H.","family":"Chohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2005.04.055_bib1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0223-5234(96)85163-4","volume":"31","author":"Supuran","year":"1996","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0223-5234(96)85164-6","volume":"31","author":"Supuran","year":"1996","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib3","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0223-5234(97)81681-9","volume":"32","author":"Supuran","year":"1997","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib4","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3109\/14756369909030332","volume":"14","author":"Popescu","year":"1999","journal-title":"J. Enzyme Inhib."},{"key":"10.1016\/j.bmcl.2005.04.055_bib5","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3109\/14756360009040708","volume":"15","author":"Scozzafava","year":"2000","journal-title":"J. Enzyme Inhib."},{"key":"10.1016\/j.bmcl.2005.04.055_bib6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1080\/14756360127571","volume":"16","author":"Ul-Hassan","year":"2001","journal-title":"J. Enzyme Inhib."},{"key":"10.1016\/j.bmcl.2005.04.055_bib7","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/14756360410001689595","volume":"19","author":"Mahmood Ul","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.bmcl.2003.09.063","volume":"14","author":"Winum","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib9","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.bmcl.2004.12.053","volume":"15","author":"Vullo","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib10","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/00061198-200404000-00015","volume":"13","author":"Whitson","year":"2004","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.bmcl.2005.04.055_bib11","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0181-5512(04)96200-6","volume":"27","author":"Renard","year":"2004","journal-title":"J. Fr. Ophthalmol."},{"key":"10.1016\/j.bmcl.2005.04.055_bib12","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1517\/13543776.13.10.1545","volume":"13","author":"Supuran","year":"2003","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2005.04.055_bib13","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1021\/jm031057+","volume":"47","author":"Vullo","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/med.20021","volume":"25","author":"Winum","year":"2005","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2005.04.055_bib15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/14756360410001689540","volume":"19","author":"Pastorekova","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib16","first-page":"49","volume":"2","author":"Supuran","year":"2004","journal-title":"Curr. Med. Chem. Cardiovasc. Hematol. Agents"},{"key":"10.1016\/j.bmcl.2005.04.055_bib17","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.bmcl.2004.12.052","volume":"15","author":"Vullo","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib18","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1016\/j.bmc.2004.03.008","volume":"12","author":"Ilies","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib19","doi-asserted-by":"crossref","first-page":"461","DOI":"10.2165\/00002018-200326070-00003","volume":"26","author":"Lyons","year":"2003","journal-title":"Drug Saf."},{"key":"10.1016\/j.bmcl.2005.04.055_bib20","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0920-1211(00)00118-2","volume":"40","author":"Stringer","year":"2000","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.bmcl.2005.04.055_bib21","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.febslet.2004.10.043","volume":"577","author":"Svastova","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib22","first-page":"2877","volume":"9","author":"Pastorek","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/j.bmcl.2005.04.055_bib23","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1006\/geno.1996.0223","volume":"33","author":"Opavsky","year":"1996","journal-title":"Genomics"},{"key":"10.1016\/j.bmcl.2005.04.055_bib24","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.bmcl.2003.12.029","volume":"14","author":"Pastorekova","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib25","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijrobp.2003.10.016","volume":"59","author":"Koukourakis","year":"2004","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.bmcl.2005.04.055_bib26","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1016\/j.bmcl.2004.01.095","volume":"14","author":"Vullo","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib27","doi-asserted-by":"crossref","first-page":"6160","DOI":"10.1158\/0008-5472.CAN-03-2224","volume":"64","author":"Robertson","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.bmcl.2005.04.055_bib28","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1200\/JCO.2003.11.132","volume":"21","author":"Swinson","year":"2003","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.bmcl.2005.04.055_bib29","series-title":"Carbonic anhydrase\u2014Its Inhibitors and Activators","author":"Supuran","year":"2004"},{"key":"10.1016\/j.bmcl.2005.04.055_bib30","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2005.04.055_bib31","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1517\/13543784.12.2.283","volume":"12","author":"Supuran","year":"2003","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.bmcl.2005.04.055_bib32","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.bmcl.2003.09.062","volume":"14","author":"Abbate","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib33","doi-asserted-by":"crossref","first-page":"164","DOI":"10.4161\/cc.3.2.618","volume":"3","author":"Potter","year":"2004","journal-title":"Cell Cycle"},{"key":"10.1016\/j.bmcl.2005.04.055_bib34","first-page":"995","volume":"24","author":"Rafajova","year":"2004","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.bmcl.2005.04.055_bib35","first-page":"1005","volume":"11","author":"Hussain","year":"2004","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.bmcl.2005.04.055_bib36","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.bmcl.2004.10.070","volume":"15","author":"Turkmen","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib37","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0960-894X(03)00091-X","volume":"13","author":"Vullo","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib38","doi-asserted-by":"crossref","first-page":"5427","DOI":"10.1016\/j.bmcl.2004.07.087","volume":"14","author":"Garaj","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.055_bib39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0162-0134(95)00086-0","volume":"62","author":"Sumalan","year":"1996","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib40","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0020-1693(97)06020-9","volume":"273","author":"Alzuet","year":"1998","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.bmcl.2005.04.055_bib41","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/S0968-0896(99)00190-X","volume":"7","author":"Borras","year":"1999","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib42","series-title":"Carbonic anhydrase\u2014Its inhibitors and activators","first-page":"183","article-title":"Metal complexes of heterocyclic sulfonamides as carbonic anhydrases inhibitors","author":"Borras","year":"2004"},{"key":"10.1016\/j.bmcl.2005.04.055_bib43","doi-asserted-by":"crossref","first-page":"13206","DOI":"10.1021\/ja047271k","volume":"126","author":"Roy","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2005.04.055_bib44","doi-asserted-by":"crossref","first-page":"10875","DOI":"10.1021\/ja047557p","volume":"126","author":"Banerjee","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2005.04.055_bib46","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah","year":"1971","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2005.04.055_bib47","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1021\/bi00629a031","volume":"16","author":"Khalifah","year":"1977","journal-title":"Biochemistry"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X05005408?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X05005408?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T05:33:58Z","timestamp":1760765638000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X05005408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":46,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0960894X05005408"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2005.04.055","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carbonic anhydrase inhibitors. Inhibition of cytosolic\/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff\u2019s bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2005.04.055","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}