{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:38:04Z","timestamp":1793317084992,"version":"4.5.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.bmcl.2005.04.056","type":"journal-article","created":{"date-parts":[[2005,5,18]],"date-time":"2005-05-18T08:01:08Z","timestamp":1116403268000},"page":"3102-3108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":142,"title":["Carbonic anhydrase inhibitors: Novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX"],"prefix":"10.1016","volume":"15","author":[{"given":"Vladimir","family":"Garaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Puccetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Fasolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Yves","family":"Winum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Montero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Vullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Innocenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2005.04.056_bib1","doi-asserted-by":"crossref","first-page":"5427","DOI":"10.1016\/j.bmcl.2004.07.087","volume":"14","author":"Garaj","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.056_bib2","year":"2004"},{"key":"10.1016\/j.bmcl.2005.04.056_bib3_1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1517\/13543776.10.5.575","volume":"10","author":"Supuran","year":"2000","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2005.04.056_bib3_2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1517\/13543776.12.2.217","volume":"12","author":"Supuran","year":"2002","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2005.04.056_bib3_3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2005.04.056_bib3_4","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1517\/13543776.14.5.667","volume":"14","author":"Scozzafava","year":"2004","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2005.04.056_bib4_1","series-title":"Carbonic Anhydrase\u2014Its Inhibitors and Activators","first-page":"253","article-title":"Cancer-Related Carbonic Anhydrase Isozymes","author":"Pastorekova","year":"2004"},{"key":"10.1016\/j.bmcl.2005.04.056_bib4_2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/14756360410001689540","volume":"19","author":"Pastorekova","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.056_bib5","doi-asserted-by":"crossref","first-page":"925","DOI":"10.2174\/0929867033457647","volume":"10","author":"Scozzafava","year":"2003","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.056_bib6","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.febslet.2004.10.043","volume":"577","author":"\u0160vastova","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmcl.2005.04.056_bib7_1","first-page":"7075","volume":"60","author":"Wykoff","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.bmcl.2005.04.056_bib7_2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/sj.bjc.6600936","volume":"89","author":"Potter","year":"2003","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.bmcl.2005.04.056_bib7_3","doi-asserted-by":"crossref","first-page":"6160","DOI":"10.1158\/0008-5472.CAN-03-2224","volume":"64","author":"Robertson","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.bmcl.2005.04.056_bib8","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1021\/jo01087a018","volume":"24","author":"D\u2019Alelio","year":"1959","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.bmcl.2005.04.056_bib9","series-title":"Carbonic Anhydrase\u2014Its Inhibitors and Activators","first-page":"67","article-title":"Development of Sulfonamide Carbonic Anhydrase Inhibitors (CAIs)","author":"Supuran","year":"2004"},{"key":"10.1016\/j.bmcl.2005.04.056_bib11","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.bmcl.2003.09.062","volume":"14","author":"Abbate","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.056_bib12","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1517\/13543784.12.2.283","volume":"12","author":"Supuran","year":"2003","journal-title":"Expert Opin. Invest. Drugs"},{"key":"10.1016\/j.bmcl.2005.04.056_bib14","series-title":"Carbonic Anhydrase\u2014From Biochemistry and Genetics to Physiology and Clinical Medicine","first-page":"1","article-title":"Structure\u2013Function Relations in Human Carbonic Anhydrase II as Studied by Site-Directed Mutagenesis","author":"Lindskog","year":"1991"},{"key":"10.1016\/j.bmcl.2005.04.056_bib15","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1021\/bi00629a031","volume":"16","author":"Khalifah","year":"1977","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2005.04.056_bib16","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0960-894X(03)00091-X","volume":"13","author":"Vullo","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.056_bib17_1","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.bmcl.2003.12.029","volume":"14","author":"Pastorekova","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2005.04.056_bib17_2","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1021\/jm031079w","volume":"47","author":"Casey","year":"2004","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2005.04.056_bib18","first-page":"2877","volume":"9","author":"Pastorek","year":"1994","journal-title":"Oncogene"},{"key":"10.1016\/j.bmcl.2005.04.056_bib19","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah","year":"1971","journal-title":"J. Biol. Chem."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X0500541X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X0500541X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T05:34:00Z","timestamp":1760765640000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X0500541X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":24,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0960894X0500541X"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2005.04.056","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carbonic anhydrase inhibitors: Novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2005.04.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}