{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:42:19Z","timestamp":1790815339320,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1016\/j.bmcl.2007.03.077","type":"journal-article","created":{"date-parts":[[2007,3,28]],"date-time":"2007-03-28T07:19:14Z","timestamp":1175066354000},"page":"3468-3472","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"title":["Penicillin-bound polyacrylate nanoparticles: Restoring the activity of \u03b2-lactam antibiotics against MRSA"],"prefix":"10.1016","volume":"17","author":[{"given":"Edward","family":"Turos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Suresh Kumar","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerriann","family":"Greenhalgh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen","family":"Ramaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sampath C.","family":"Abeylath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyoung","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Dickey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel V.","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2007.03.077_bib1","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1038\/431892a","volume":"431","author":"Zafeiris","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2007.03.077_bib2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1473-3099(05)70086-4","volume":"5","author":"Norrby","year":"2005","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.bmcl.2007.03.077_bib3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/nrmicro727","volume":"1","author":"Walsh","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bmcl.2007.03.077_bib4","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1023\/A:1016054306763","volume":"13","author":"Patel","year":"1996","journal-title":"Pharm. Res."},{"key":"10.1016\/j.bmcl.2007.03.077_bib5","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2007.03.077_bib6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0378-5173(87)90080-9","volume":"35","author":"Michelland","year":"1987","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.bmcl.2007.03.077_bib7","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1128\/AAC.33.9.1540","volume":"33","author":"Fattal","year":"1989","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bmcl.2007.03.077_bib8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0168-3659(92)90081-2","volume":"19","author":"Couvreur","year":"1992","journal-title":"J. Controlled Release"},{"key":"10.1016\/j.bmcl.2007.03.077_bib9","first-page":"2","volume":"41","author":"Couvreur","year":"1995","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.bmcl.2007.03.077_bib10","first-page":"173","volume":"39","author":"Alle\u2019mann","year":"1993","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.bmcl.2007.03.077_bib11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0378-5173(94)90399-9","volume":"111","author":"Cavallaro","year":"1994","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.bmcl.2007.03.077_bib12","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0142-9612(97)00246-9","volume":"19","author":"Fontana","year":"1998","journal-title":"Biomaterials"},{"key":"10.1016\/j.bmcl.2007.03.077_bib13","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1016\/S0142-9612(01)00030-8","volume":"22","author":"Fontana","year":"2001","journal-title":"Biomaterials"},{"key":"10.1016\/j.bmcl.2007.03.077_bib14","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0378-5173(00)00546-9","volume":"208","author":"Santos-Magalhaes","year":"2000","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.bmcl.2007.03.077_bib15","first-page":"5392","volume":"17","author":"Turos","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2007.03.077_bib16","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1016\/S0960-894X(02)00343-8","volume":"12","author":"Turos","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2007.03.077_bib17","doi-asserted-by":"crossref","first-page":"6289","DOI":"10.1016\/j.bmc.2005.08.011","volume":"13","author":"Turos","year":"2005","journal-title":"Bioorg. Med. Chem."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X07003800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X07003800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T05:49:17Z","timestamp":1760766557000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X07003800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S0960894X07003800"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2007.03.077","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Penicillin-bound polyacrylate nanoparticles: Restoring the activity of \u03b2-lactam antibiotics against MRSA","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2007.03.077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}