{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T10:29:58Z","timestamp":1791023398144,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.bmcl.2008.12.082","type":"journal-article","created":{"date-parts":[[2008,12,26]],"date-time":"2008-12-26T04:33:58Z","timestamp":1230266038000},"page":"1155-1158","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Carbonic anhydrase inhibitors: The membrane-associated isoform XV is highly inhibited by inorganic anions"],"prefix":"10.1016","volume":"19","author":[{"given":"Alessio","family":"Innocenti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Hilvo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seppo","family":"Parkkila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2008.12.082_bib1a","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1016\/S0960-894X(03)00581-X","volume":"13","author":"Franchi","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib1b","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1080\/1475636031000138732","volume":"18","author":"Vullo","year":"2003","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib1c","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1074\/jbc.M308984200","volume":"279","author":"Lehtonen","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib1d","doi-asserted-by":"crossref","first-page":"5435","DOI":"10.1016\/j.bmcl.2004.07.086","volume":"14","author":"Innocenti","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib1e","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.bmcl.2004.11.056","volume":"15","author":"Innocenti","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib1f","doi-asserted-by":"crossref","first-page":"5769","DOI":"10.1016\/j.bmcl.2004.09.063","volume":"14","author":"Innocenti","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2a","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1016\/j.bmcl.2006.03.078","volume":"16","author":"Vullo","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2b","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.bmcl.2006.11.028","volume":"17","author":"Nishimori","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2c","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.bmcl.2006.12.113","volume":"17","author":"Innocenti","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2d","doi-asserted-by":"crossref","first-page":"6742","DOI":"10.1016\/j.bmc.2007.08.008","volume":"15","author":"Nishimori","year":"2007","journal-title":"Bioorg Med Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2_5","unstructured":"Nishimori, I.; Minakuchi, T.; Onishi, S.; Vullo, D.; Cecchi, A.; Scozzafava, A.; Supuran, C. T. J. Enzymr Inhib. Med. Chem. 2008, 23."},{"key":"10.1016\/j.bmcl.2008.12.082_bib2f","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.bmcl.2004.11.057","volume":"15","author":"Innocenti","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib3","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmcl.2008.12.082_bib4a","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2008.12.082_bib4b","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1517\/13543776.12.2.217","volume":"12","author":"Supuran","year":"2002","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2008.12.082_bib4c","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/14756360410001689540","volume":"18","author":"Pastorekova","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib4d","series-title":"Carbonic Anhydrase: Its Inhibitors and Activators","first-page":"1","year":"2004"},{"key":"10.1016\/j.bmcl.2008.12.082_bib5","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1139\/o06-184","volume":"84","author":"Casey","year":"2006","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.bmcl.2008.12.082_bib6a","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/09687860400014872","volume":"21","author":"Morgan","year":"2004","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.bmcl.2008.12.082_bib6b","doi-asserted-by":"crossref","first-page":"C1522","DOI":"10.1152\/ajpcell.00115.2002","volume":"283","author":"Sterling","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bmcl.2008.12.082_bib6c","doi-asserted-by":"crossref","first-page":"12321","DOI":"10.1021\/bi0353124","volume":"42","author":"Alvarez","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2008.12.082_bib7a","doi-asserted-by":"crossref","first-page":"27799","DOI":"10.1074\/jbc.M800938200","volume":"283","author":"Hilvo","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib7b","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.febslet.2004.10.043","volume":"577","author":"\u0160vastov\u00e1","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib8","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1042\/BJ20051102","volume":"392","author":"Hilvo","year":"2005","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmcl.2008.12.082_bib9","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1021\/bi962663s","volume":"36","author":"Baird","year":"1997","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2008.12.082_bib10","doi-asserted-by":"crossref","first-page":"672","DOI":"10.2174\/138161208783877811","volume":"14","author":"Hilvo","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bmcl.2008.12.082_bib13","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1021\/jm011131t","volume":"45","author":"Abbate","year":"2002","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib14","unstructured":"Hilvo, M.; Salzano, A. M.; Innocenti, A.; Kulomaa, M. S.; Scozzafava, A.; Scaloni, A.; Parkkila, S.; Supuran, C. T. J. Med. Chem. 2008, 51."},{"key":"10.1016\/j.bmcl.2008.12.082_bib15","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.bmcl.2005.03.032","volume":"15","author":"De Simone","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib16","doi-asserted-by":"crossref","first-page":"4866","DOI":"10.1016\/j.bmcl.2007.06.044","volume":"17","author":"Temperini","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib17","doi-asserted-by":"crossref","first-page":"8329","DOI":"10.1021\/ja061574s","volume":"128","author":"Alterio","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2008.12.082_bib18a","doi-asserted-by":"crossref","first-page":"3230","DOI":"10.1021\/jm800121c","volume":"51","author":"D\u2019Ambrosio","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib18b","doi-asserted-by":"crossref","first-page":"5721","DOI":"10.1021\/jm050333c","volume":"48","author":"Menchise","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib18c","doi-asserted-by":"crossref","first-page":"5544","DOI":"10.1021\/jm060531j","volume":"49","author":"De Simone","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2008.12.082_bib18d","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0960-894X(03)00029-5","volume":"13","author":"Casini","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2008.12.082_bib18e","doi-asserted-by":"crossref","first-page":"7024","DOI":"10.1021\/jm060807n","volume":"49","author":"Winum","year":"2006","journal-title":"J. Med. Chem."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X08016065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X08016065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:02:02Z","timestamp":1760767322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X08016065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0960894X08016065"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2008.12.082","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carbonic anhydrase inhibitors: The membrane-associated isoform XV is highly inhibited by inorganic anions","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2008.12.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}