{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:48:32Z","timestamp":1778878112185,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.bmcl.2010.01.004","type":"journal-article","created":{"date-parts":[[2010,1,12]],"date-time":"2010-01-12T04:59:45Z","timestamp":1263272385000},"page":"1360-1362","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Design and study of peptide-based inhibitors of amylin cytotoxicity"],"prefix":"10.1016","volume":"20","author":[{"given":"Karen","family":"Muthusamy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per I.","family":"Arvidsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Govender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik G.","family":"Kruger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn E.M.","family":"Maguire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thavendran","family":"Govender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2010.01.004_bib1","unstructured":"World Health Organisation, 2008."},{"key":"10.1016\/j.bmcl.2010.01.004_bib2","first-page":"528","volume":"5","author":"Opie","year":"1901","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bmcl.2010.01.004_bib3","doi-asserted-by":"crossref","first-page":"8628","DOI":"10.1073\/pnas.84.23.8628","volume":"84","author":"Cooper","year":"1987","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bmcl.2010.01.004_bib4","doi-asserted-by":"crossref","first-page":"7763","DOI":"10.1073\/pnas.85.20.7763","volume":"85","author":"Cooper","year":"1988","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bmcl.2010.01.004_bib5","first-page":"101","volume":"32","author":"Martin","year":"2006","journal-title":"Diabetes Educ."},{"key":"10.1016\/j.bmcl.2010.01.004_bib6","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1152\/physrev.00037.2003","volume":"84","author":"Grant","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bmcl.2010.01.004_bib7","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1006\/jmbi.1999.2646","volume":"287","author":"Kayed","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib8","doi-asserted-by":"crossref","first-page":"13505","DOI":"10.1021\/bi701427q","volume":"46","author":"Luca","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2010.01.004_bib9","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1074\/jbc.271.4.1988","volume":"271","author":"Mirzabekov","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2010.01.004_bib10","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0006-8993(95)00148-J","volume":"676","author":"Mattson","year":"1995","journal-title":"Brain Res."},{"key":"10.1016\/j.bmcl.2010.01.004_bib11","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1042\/bj3220859","volume":"322","author":"Tomiyama","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmcl.2010.01.004_bib12","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1046\/j.1432-1327.1998.2510208.x","volume":"251","author":"Kapurniotu","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bmcl.2010.01.004_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1042\/bj3430053","volume":"343","author":"Bai","year":"1999","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmcl.2010.01.004_bib14","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0002-9440(10)65360-6","volume":"154","author":"Hiddinga","year":"1999","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib15","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/jmbi.2001.5244","volume":"315","author":"Kapurniotu","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib16","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.chembiol.2005.05.010","volume":"12","author":"Tatarek-Nossol","year":"2005","journal-title":"Chem. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib17","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1002\/anie.200604056","volume":"46","author":"Yan","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmcl.2010.01.004_bib18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2337\/diabetes.48.3.491","volume":"48","author":"Janson","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.bmcl.2010.01.004_bib19","doi-asserted-by":"crossref","first-page":"11338","DOI":"10.1021\/bi020314u","volume":"41","author":"Anguiano","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2010.01.004_bib20","doi-asserted-by":"crossref","first-page":"46363","DOI":"10.1074\/jbc.C400260200","volume":"279","author":"Kayed","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2010.01.004_bib21","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2337\/db06-0734","volume":"56","author":"Ritzel","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.bmcl.2010.01.004_bib22","doi-asserted-by":"crossref","first-page":"E1317","DOI":"10.1152\/ajpendo.00082.2006","volume":"291","author":"Meier","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bmcl.2010.01.004_bib23","doi-asserted-by":"crossref","first-page":"4285","DOI":"10.1002\/1521-3765(20020916)8:18<4285::AID-CHEM4285>3.0.CO;2-0","volume":"8","author":"Rijkers","year":"2002","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.bmcl.2010.01.004_bib24","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1073\/pnas.87.13.5036","volume":"87","author":"Westermark","year":"1990","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bmcl.2010.01.004_bib25","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1006\/jmbi.2001.4593","volume":"308","author":"Jaikaran","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib26","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.jmb.2005.10.052","volume":"355","author":"Abedini","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib27","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1073\/pnas.0507471103","volume":"103","author":"Yan","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bmcl.2010.01.004_bib28","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0022-2836(02)00164-X","volume":"318","author":"Scrocchi","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib29","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S1047-8477(02)00630-5","volume":"141","author":"Scrocchi","year":"2003","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bmcl.2010.01.004_bib30","first-page":"1","author":"Potter","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bmcl.2010.01.004_bib31","doi-asserted-by":"crossref","first-page":"8002","DOI":"10.1021\/jm901092h","volume":"52","author":"Bose","year":"2009","journal-title":"J. Med. Chem."}],"container-title":["Bioorganic &amp; Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10000065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10000065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:09:53Z","timestamp":1760767793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X10000065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0960894X10000065"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.01.004","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Design and study of peptide-based inhibitors of amylin cytotoxicity","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}