{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:08:09Z","timestamp":1790964489247,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":1080,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Wellcome Trust","award":["083481"],"award-info":[{"award-number":["083481"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01 AI34432"],"award-info":[{"award-number":["R01 AI34432"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000928","name":"Welch Foundation","doi-asserted-by":"crossref","award":["I-1257"],"award-info":[{"award-number":["I-1257"]}],"id":[{"id":"10.13039\/100000928","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.bmcl.2010.06.070","type":"journal-article","created":{"date-parts":[[2010,6,18]],"date-time":"2010-06-18T04:35:49Z","timestamp":1276835749000},"page":"4364-4366","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif"],"prefix":"10.1016","volume":"20","author":[{"given":"Nina","family":"Klee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pui Ee","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Baraga\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farah El","family":"Mazouni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret A.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian H.","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2010.06.070_bib1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nrd1824","volume":"4","author":"Pink","year":"2005","journal-title":"Nat. Rev. Drug Disc."},{"key":"10.1016\/j.bmcl.2010.06.070_bib2","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1111\/j.1432-1033.1997.01102.x","volume":"247","author":"de Koning","year":"1997","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib3","doi-asserted-by":"crossref","first-page":"9486","DOI":"10.1074\/jbc.273.16.9486","volume":"273","author":"de Koning","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib4","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/361173a0","volume":"361","author":"Carter","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2010.06.070_bib5","doi-asserted-by":"crossref","first-page":"28153","DOI":"10.1074\/jbc.270.47.28153","volume":"270","author":"Carter","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0065-308X(06)63002-9","volume":"63","author":"Barrett","year":"2006","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib7","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1124\/mol.106.024653","volume":"70","author":"Lanteri","year":"2006","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib8","first-page":"586","volume":"65","author":"de Koning","year":"2001","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib9","first-page":"232","volume":"19","author":"Bray","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib10","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1124\/mol.106.031351","volume":"71","author":"Bridges","year":"2007","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1042\/bj2340249","volume":"234","author":"Pegg","year":"1986","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmcl.2010.06.070_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj20031327","volume":"376","author":"Wallace","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.bmcl.2010.06.070_bib13","doi-asserted-by":"crossref","first-page":"15174","DOI":"10.1021\/bi9915115","volume":"38","author":"Grishin","year":"1999","journal-title":"J. Biochemistry"},{"key":"10.1016\/j.bmcl.2010.06.070_bib14","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1021\/jm00086a003","volume":"35","author":"Stanek","year":"1992","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib15","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1128\/AAC.49.7.2857-2864.2005","volume":"49","author":"Gupta","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bmcl.2010.06.070_bib16","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1128\/AAC.01055-06","volume":"51","author":"Singh","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bmcl.2010.06.070_bib17","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.pt.2003.09.002","volume":"19","author":"Fairlamb","year":"2003","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.bmcl.2010.06.070_bib18","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S0960-894X(98)00095-X","volume":"8","author":"Tye","year":"1998","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.06.070_bib19","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1021\/jm010854+","volume":"44","author":"Klenke","year":"2001","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib20","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1128\/AAC.48.5.1733-1738.2004","volume":"48","author":"Stewart","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bmcl.2010.06.070_bib21","doi-asserted-by":"crossref","first-page":"5570","DOI":"10.1021\/jm050177+","volume":"48","author":"Baliani","year":"2005","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib22","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1039\/b813394h","volume":"7","author":"Baliani","year":"2009","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib23","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1016\/j.bmc.2009.01.058","volume":"17","author":"Chollet","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib24","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1139\/v60-050","volume":"38","author":"McKay","year":"1960","journal-title":"Can. J. Chem."},{"key":"10.1016\/j.bmcl.2010.06.070_bib25","doi-asserted-by":"crossref","first-page":"7187","DOI":"10.1016\/S0040-4039(00)79283-5","volume":"34","author":"Romeo","year":"1993","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmcl.2010.06.070_bib26","doi-asserted-by":"crossref","first-page":"13662","DOI":"10.1021\/bi00250a016","volume":"46","author":"Osterman","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2010.06.070_bib27","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1128\/EC.2.5.1003-1008.2003","volume":"2","author":"Matovu","year":"2003","journal-title":"Eukaryot. Cell"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10008449?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10008449?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:14:49Z","timestamp":1760768089000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X10008449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":27,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0960894X10008449"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.06.070","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.06.070","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}