{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:12:35Z","timestamp":1792091555442,"version":"4.4.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.bmcl.2010.12.082","type":"journal-article","created":{"date-parts":[[2010,12,25]],"date-time":"2010-12-25T05:28:12Z","timestamp":1293254892000},"page":"1214-1217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Synthesis and antitubercular evaluation of novel substituted aryl and thiophenyl tethered dihydro-6H-quinolin-5-ones"],"prefix":"10.1016","volume":"21","author":[{"given":"Srinivas","family":"Kantevari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhosh Reddy","family":"Patpi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramanian","family":"Sridhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perumal","family":"Yogeeswari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmarajan","family":"Sriram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2010.12.082_b0095","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1126\/science.1184784","volume":"328","author":"Russell","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2010.12.082_b0100","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nrmicro1538","volume":"5","author":"Russell","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bmcl.2010.12.082_b0105","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/nm0505-578a","volume":"11","author":"Kaufmann","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.bmcl.2010.12.082_b0110","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1038\/82139","volume":"6","author":"Manabe1","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.bmcl.2010.12.082_b0115","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3923\/ajbs.2011.101.115","volume":"4","author":"Nikalie","year":"2011","journal-title":"Asian J. Biol. Sci."},{"key":"10.1016\/j.bmcl.2010.12.082_b0120","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nrmicro1816","volume":"6","author":"Sacchettini","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bmcl.2010.12.082_b0015","unstructured":"Global tuberculosis control: a short update to the 2009 report http:\/\/www.who.int\/tb\/publications\/global_report\/2009\/update\/en\/index.html."},{"key":"10.1016\/j.bmcl.2010.12.082_b0125","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S1472-9792(08)70032-5","volume":"88","author":"Showalter","year":"2008","journal-title":"Tuberculosis"},{"key":"10.1016\/j.bmcl.2010.12.082_b0130","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.mib.2004.08.011","volume":"7","author":"Duncan","year":"2004","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.bmcl.2010.12.082_b0135","doi-asserted-by":"crossref","first-page":"6914","DOI":"10.1016\/j.bmc.2010.07.010","volume":"18","author":"Muddassar","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0140","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1016\/j.ejmech.2010.04.022","volume":"45","author":"Eswaran","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0145","doi-asserted-by":"crossref","first-page":"4681","DOI":"10.1016\/j.bmc.2009.04.069","volume":"17","author":"Upadhayaya","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0150","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.biopha.2007.10.004","volume":"63","author":"Senthilkumar","year":"2009","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bmcl.2010.12.082_b0155","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ejmech.2008.02.031","volume":"44","author":"Senthilkumar","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0160","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ejmech.2009.09.033","volume":"45","author":"Sriram","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0165","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1021\/jm701066a","volume":"51","author":"Hassani","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0170","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1016\/j.bmc.2010.03.021","volume":"18","author":"Mulchin","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0175","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alves, R. S. B.; Kaiser, C. R.; Louren\u00e7o, M. C. S.; de Souza, M. V. N.; Wardell, J. L.; Wardell, S. M. S. V.; da Silva, A. D. Eur. J. Med. Chem. 2010, 45, 6095","DOI":"10.1016\/j.ejmech.2010.09.024"},{"key":"10.1016\/j.bmcl.2010.12.082_b0180","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1016\/j.ejmech.2010.05.035","author":"Manna","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0185","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.ejmech.2009.11.011","volume":"45","author":"Balamurugan","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0190","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1016\/j.bmcl.2009.04.029","volume":"19","author":"Karthikeyan","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0195","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.ejmech.2006.11.007","volume":"42","author":"Ashalatha","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0200","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00706-007-0793-0","volume":"139","author":"Ouf","year":"2008","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0205","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s12039-009-0034-7","volume":"121","author":"Sheety","year":"2009","journal-title":"J. Chem. Sci."},{"key":"10.1016\/j.bmcl.2010.12.082_b0210","doi-asserted-by":"crossref","first-page":"3352","DOI":"10.1016\/j.bmcl.2010.04.025","volume":"20","author":"Manikannan","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0215","doi-asserted-by":"crossref","first-page":"6191","DOI":"10.1016\/j.tetlet.2009.08.085","volume":"50","author":"Balamurugan","year":"2009","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0220","doi-asserted-by":"crossref","first-page":"8463","DOI":"10.1016\/S0040-4020(03)01201-8","volume":"59","author":"Elassar","year":"2003","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmcl.2010.12.082_b0225","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1002\/jhet.5570410402","volume":"41","author":"Negri","year":"2004","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0230","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.1039\/b805680c","author":"Lieby-Muller","year":"2008","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bmcl.2010.12.082_b0235","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3390\/molecules14010068","volume":"14","author":"Alnajjar","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.bmcl.2010.12.082_b0240","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.3987\/REV-07-625","volume":"75","author":"Riyadh","year":"2008","journal-title":"Heterocycles"},{"key":"10.1016\/j.bmcl.2010.12.082_b0245","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1002\/jhet.5570390528","volume":"39","author":"Al-Saleh","year":"2002","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0055","doi-asserted-by":"crossref","first-page":"13024","DOI":"10.1016\/j.tet.2007.10.014","volume":"63","author":"Kantevari","year":"2007","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmcl.2010.12.082_b0060","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1055\/s-0030-1258038","author":"Kantevari","year":"2010","journal-title":"Synlett"},{"key":"10.1016\/j.bmcl.2010.12.082_b0250","doi-asserted-by":"crossref","unstructured":"Kantevari, S.; Addala, D.; Sridhar, B.; Synthesis, 2010, 3745","DOI":"10.1055\/s-0030-1258236"},{"key":"10.1016\/j.bmcl.2010.12.082_b0065","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1002\/jhet.5570450424","author":"Kantevari","year":"2008","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0255","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1016\/j.bmcl.2006.12.116","volume":"17","author":"Powell","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0260","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1016\/j.bmcl.2004.04.079","volume":"14","author":"Hayakawa","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0265","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.bmcl.2005.01.066","volume":"15","author":"Gopalsamy","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2010.12.082_b0270","doi-asserted-by":"crossref","first-page":"9421","DOI":"10.1016\/j.tet.2009.08.084","volume":"65","author":"Khalil","year":"2009","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bmcl.2010.12.082_b0080","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/jhet.5570440212","volume":"44","author":"Baraldi","year":"2007","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.bmcl.2010.12.082_b0085","first-page":"1346","author":"Srinivas","year":"2009","journal-title":"Synlett"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10018469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X10018469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:19:51Z","timestamp":1760768391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X10018469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0960894X10018469"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.12.082","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and antitubercular evaluation of novel substituted aryl and thiophenyl tethered dihydro-6H-quinolin-5-ones","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2010.12.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}