{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T14:24:17Z","timestamp":1772893457342,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic &amp; Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.bmcl.2011.12.143","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T11:30:38Z","timestamp":1326195038000},"page":"1582-1586","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Synthesis and human telomeric G-quadruplex DNA-binding activity of glucosaminosides of shikonin\/alkannin"],"prefix":"10.1016","volume":"22","author":[{"given":"Hao","family":"He","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Ping","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Hong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2011.12.143_b0005","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/(SICI)1521-3773(19990201)38:3<270::AID-ANIE270>3.0.CO;2-0","volume":"38","author":"Papageorgiou","year":"1999","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmcl.2011.12.143_b0010","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.2174\/138527206778742704","volume":"10","author":"Papageorgiou","year":"2006","journal-title":"Curr. Org. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0015","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.2174\/092986708786848532","volume":"15","author":"Papageorgiou","year":"2008","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0020","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1021\/np50045a014","volume":"49","author":"Tanaka","year":"1986","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.bmcl.2011.12.143_b0025","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1248\/cpb.25.2392","volume":"25","author":"Sankawa","year":"1977","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.bmcl.2011.12.143_b0030","first-page":"250","volume":"7","author":"Bhakuni","year":"1969","journal-title":"Exp. Biol."},{"key":"10.1016\/j.bmcl.2011.12.143_b0035","first-page":"1","volume":"4","author":"Driscoll","year":"1974","journal-title":"Cancer Chemother. Rep. Part 2"},{"key":"10.1016\/j.bmcl.2011.12.143_b0040","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/0006-2952(86)90157-7","volume":"35","author":"Miler","year":"1986","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bmcl.2011.12.143_b0045","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1038\/cr.2008.86","volume":"18","author":"Mao","year":"2008","journal-title":"Cell Res."},{"key":"10.1016\/j.bmcl.2011.12.143_b0050","doi-asserted-by":"crossref","first-page":"8871","DOI":"10.1158\/0008-5472.CAN-08-1972","volume":"68","author":"Liu","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.bmcl.2011.12.143_b0055","doi-asserted-by":"crossref","first-page":"490","DOI":"10.4161\/auto.4592","volume":"3","author":"Hu","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.bmcl.2011.12.143_b0060","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1158\/1535-7163.MCT-06-0511","volume":"6","author":"Han","year":"2007","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.bmcl.2011.12.143_b0065","first-page":"783","volume":"18","author":"Hisa","year":"1998","journal-title":"Anticancer Res."},{"key":"10.1016\/j.bmcl.2011.12.143_b0070","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1349-7006.2008.01049.x","volume":"100","author":"Komi","year":"2009","journal-title":"Cancer Sci."},{"key":"10.1016\/j.bmcl.2011.12.143_b0075","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1021\/jm00006a025","volume":"38","author":"Ahn","year":"1995","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0080","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1002\/ijc.21943","volume":"119","author":"Yang","year":"2006","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bmcl.2011.12.143_b0085","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0304-3835(03)00239-8","volume":"200","author":"Singh","year":"2003","journal-title":"Cancer Lett."},{"key":"10.1016\/j.bmcl.2011.12.143_b0090","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/00001813-200310000-00002","volume":"14","author":"Nakaya","year":"2003","journal-title":"Anticancer Drugs"},{"key":"10.1016\/j.bmcl.2011.12.143_b0095","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0960-894X(02)00158-0","volume":"12","author":"Lu","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2011.12.143_b0100","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1126\/science.7605428","volume":"266","author":"Kim","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2011.12.143_b0105","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.tcb.2009.05.002","volume":"19","author":"Lipps","year":"2009","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bmcl.2011.12.143_b0110","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/350718a0","volume":"350","author":"Zahler","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2011.12.143_b0115","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1021\/jm970199z","volume":"40","author":"Sun","year":"1997","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0120","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1021\/cr940283b","volume":"96","author":"Dwek","year":"1996","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmcl.2011.12.143_b0125","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1126\/science.1059820","volume":"291","author":"Bertozzi","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2011.12.143_b0130","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1016\/j.ejmech.2010.02.002","volume":"45","author":"Su","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0135","unstructured":"The enantiomeric ratio was determined by chiral HPLC and the specific rotation of the mixture is [\u03b1]D20=126.5 (c 0.0322, CHCl3)."},{"key":"10.1016\/j.bmcl.2011.12.143_b0140","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S1074-5521(02)00188-6","volume":"9","author":"Xi","year":"2002","journal-title":"Chem. Biol."},{"key":"10.1016\/j.bmcl.2011.12.143_b0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1387-3806(02)00585-7","volume":"216","author":"Daniel","year":"2002","journal-title":"Int. J. Mass Spectrom."},{"key":"10.1016\/j.bmcl.2011.12.143_b0165","doi-asserted-by":"crossref","first-page":"3608","DOI":"10.1021\/ja055936s","volume":"128","author":"Rueda","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2011.12.143_b0170","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1002\/rcm.778","volume":"16","author":"Rosu","year":"2002","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.bmcl.2011.12.143_b0175","doi-asserted-by":"crossref","first-page":"10361","DOI":"10.1021\/bi034531m","volume":"42","author":"Rosu","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2011.12.143_b0180","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1016\/j.bmcl.2004.07.037","volume":"14","author":"Chen","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2011.12.143_b0185","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1002\/cbic.200800256","volume":"9","author":"Bai","year":"2008","journal-title":"ChemBioChem"},{"key":"10.1016\/j.bmcl.2011.12.143_b0190","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s00216-008-2302-7","volume":"392","author":"Bai","year":"2008","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0195","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1021\/ja065989p","volume":"129","author":"Gabelica","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2011.12.143_b0200","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.bmc.2005.07.069","volume":"14","author":"Qin","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0205","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1016\/j.bmcl.2004.10.098","volume":"15","author":"Chen","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2011.12.143_b0210","first-page":"485","volume":"2011","author":"Bhadra","year":"1810","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bmcl.2011.12.143_b0215","doi-asserted-by":"crossref","first-page":"5439","DOI":"10.1016\/j.bmc.2006.05.012","volume":"14","author":"Bai","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0220","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1016\/j.bmc.2006.03.004","volume":"14","author":"Long","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0225","doi-asserted-by":"crossref","first-page":"5695","DOI":"10.1093\/nar\/gkn569","volume":"36","author":"Yu","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bmcl.2011.12.143_b0230","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1021\/jm9014795","volume":"53","author":"Yu","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2011.12.143_b0235","doi-asserted-by":"crossref","first-page":"8209","DOI":"10.1002\/chem.201100272","volume":"17","author":"Zhao","year":"2011","journal-title":"Chem. Eur. J."}],"container-title":["Bioorganic &amp; Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X12000327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X12000327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:30:59Z","timestamp":1760769059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X12000327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0960894X12000327"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2011.12.143","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and human telomeric G-quadruplex DNA-binding activity of glucosaminosides of shikonin\/alkannin","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2011.12.143","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}