{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T16:56:12Z","timestamp":1775235372526,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NIMH PDSP","award":["HHSN-271-2008-00025-C"],"award-info":[{"award-number":["HHSN-271-2008-00025-C"]}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Nova Scotia Health Research Foundation, Faculty of Medicine"},{"DOI":"10.13039\/501100005785","name":"Dalhousie University Department of Medicine","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005785","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007670","name":"Dalhousie Medical Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007670","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.bmcl.2013.04.082","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T23:04:50Z","timestamp":1367967890000},"page":"3822-3825","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems"],"prefix":"10.1016","volume":"23","author":[{"given":"Sultan","family":"Darvesh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian R.","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Earl","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2013.04.082_b0005","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.2174\/138945006778226552","volume":"7","author":"Mitchell","year":"2006","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.bmcl.2013.04.082_b0010","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S1734-1140(12)70726-0","volume":"64","author":"Jaszczyszyn","year":"2012","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bmcl.2013.04.082_b0015","series-title":"Chlorpromazine in Psychiatry: A Study of Therapeutic Innovation","author":"Swazey","year":"1974"},{"key":"10.1016\/j.bmcl.2013.04.082_b0020","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1016\/j.ejmech.2011.05.013","volume":"46","author":"Pluta","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0025","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1021\/bi00052a003","volume":"32","author":"Vellom","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2013.04.082_b0030","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.abb.2013.01.003","volume":"532","author":"Sezgin","year":"2013","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bmcl.2013.04.082_b0035","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1016\/j.ejmech.2011.03.003","volume":"46","author":"Gonzalez-Munoz","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0040","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.abb.2007.02.029","volume":"461","author":"Kucukkilinc","year":"2007","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bmcl.2013.04.082_b0045","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/1475636021000003165","volume":"17","author":"Debord","year":"2002","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0050","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/0006-2952(92)90465-U","volume":"44","author":"Spinedi","year":"1992","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bmcl.2013.04.082_b0055","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(76)91936-X","volume":"2","author":"Davies","year":"1976","journal-title":"Lancet"},{"key":"10.1016\/j.bmcl.2013.04.082_b0060","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1126\/science.7046051","volume":"217","author":"Bartus","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2013.04.082_b0065","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1126\/science.6338589","volume":"219","author":"Coyle","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.bmcl.2013.04.082_b0070","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1365-2990.1978.tb00545.x","volume":"4","author":"Perry","year":"1978","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.bmcl.2013.04.082_b0075","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2174\/156720510791383868","volume":"7","author":"Darvesh","year":"2010","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.bmcl.2013.04.082_b0080","first-page":"477","article-title":"J. Neuropathol","volume":"24","author":"Friede","year":"1965","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bmcl.2013.04.082_b0085","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0006-8993(89)90419-8","volume":"498","author":"Geula","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.bmcl.2013.04.082_b0090","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/ana.410360506","volume":"36","author":"Mesulam","year":"1994","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bmcl.2013.04.082_b0145","first-page":"CD005593","author":"Birks","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.bmcl.2013.04.082_b0100","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s12603-009-0046-5","volume":"13","author":"Wischik","year":"2009","journal-title":"J. Nutr. Health Aging"},{"key":"10.1016\/j.bmcl.2013.04.082_b0105","doi-asserted-by":"crossref","first-page":"8850","DOI":"10.1021\/bi700411k","volume":"46","author":"Necula","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2013.04.082_b0110","doi-asserted-by":"crossref","first-page":"11213","DOI":"10.1073\/pnas.93.20.11213","volume":"93","author":"Wischik","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmcl.2013.04.082_b0115","doi-asserted-by":"crossref","first-page":"7614","DOI":"10.1074\/jbc.M408714200","volume":"280","author":"Taniguchi","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0150","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1002\/anie.201208290","volume":"52","author":"Akoury","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmcl.2013.04.082_b0125","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.bmc.2004.09.059","volume":"13","author":"Darvesh","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0130","doi-asserted-by":"crossref","first-page":"6367","DOI":"10.1016\/j.bmc.2007.06.060","volume":"15","author":"Darvesh","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0135","doi-asserted-by":"crossref","first-page":"4200","DOI":"10.1021\/jm8002075","volume":"51","author":"Darvesh","year":"2008","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.04.082_b0140","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1016\/0006-2952(73)90196-2","volume":"22","author":"Cheng","year":"1973","journal-title":"Biochem. Pharmacol."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X13005726?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X13005726?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:44:20Z","timestamp":1760769860000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X13005726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":28,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0960894X13005726"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.04.082","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.04.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}