{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:40:07Z","timestamp":1790062807004,"version":"4.0.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.bmcl.2013.06.034","type":"journal-article","created":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T01:46:50Z","timestamp":1371692810000},"page":"4587-4590","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Are hERG channel blockers also phospholipidosis inducers?"],"prefix":"10.1016","volume":"23","author":[{"given":"Hongmao","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menghang","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sampada A.","family":"Shahane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit","family":"Jadhav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Austin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruili","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2013.06.034_b0005","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/nrd1108","volume":"2","author":"Fermini","year":"2003","journal-title":"Nat. Rev. Drug Dis."},{"key":"10.1016\/j.bmcl.2013.06.034_b0010","first-page":"574","volume":"29","author":"Towbin","year":"2001","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.bmcl.2013.06.034_b0015","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00001573-200201000-00007","volume":"17","author":"Antzelevitch","year":"2002","journal-title":"Curr. Opin. Cardiol."},{"key":"10.1016\/j.bmcl.2013.06.034_b0020","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nature01580","volume":"423","author":"Jiang","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2013.06.034_b0025","doi-asserted-by":"crossref","first-page":"12329","DOI":"10.1073\/pnas.210244497","volume":"97","author":"Mitcheson","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmcl.2013.06.034_b0030","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1359-6446(04)03278-7","volume":"10","author":"Aronov","year":"2005","journal-title":"Drug Discovery Today"},{"key":"10.1016\/j.bmcl.2013.06.034_b0035","doi-asserted-by":"crossref","first-page":"5533","DOI":"10.1016\/j.febslet.2006.08.061","volume":"580","author":"Anderson","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bmcl.2013.06.034_b0040","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/0006-2952(78)90435-5","volume":"27","author":"Lullmann","year":"1978","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bmcl.2013.06.034_b0045","first-page":"347","volume":"55","author":"Ploemen","year":"2004","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.bmcl.2013.06.034_b0050","doi-asserted-by":"crossref","first-page":"80ps16","DOI":"10.1126\/scitranslmed.3001862","volume":"3","author":"Huang","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bmcl.2013.06.034_b0055","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.taap.2011.02.016","volume":"252","author":"Xia","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bmcl.2013.06.034_b0060","unstructured":"Shahane, S.; Huang, R.; Gerhold, D.; Austin, C. P.; Xia, M. J. Biomol. Screen. Submitted."},{"key":"10.1016\/j.bmcl.2013.06.034_b0065","doi-asserted-by":"crossref","first-page":"11473","DOI":"10.1073\/pnas.0604348103","volume":"103","author":"Inglese","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmcl.2013.06.034_b0070","unstructured":"http:\/\/accelrys.com\/products\/pipeline-pilot\/; Accessed 04\/24\/2011."},{"key":"10.1016\/j.bmcl.2013.06.034_b0075","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1021\/jm00109a024","volume":"34","author":"Makriyannis","year":"1991","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2013.06.034_b0080","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/259242a0","volume":"259","author":"Huang","year":"1976","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2013.06.034_b0085","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1073\/pnas.72.9.3477","volume":"72","author":"Yeagle","year":"1975","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bmcl.2013.06.034_b0090","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0005-2736(97)00078-3","volume":"1328","author":"Mavromoustakos","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bmcl.2013.06.034_b0095","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1517\/14728222.11.3.321","volume":"11","author":"Witchel","year":"2007","journal-title":"Expert Opin. Ther. Targets"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X13007439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X13007439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:45:54Z","timestamp":1760769954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X13007439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":19,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S0960894X13007439"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.06.034","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Are hERG channel blockers also phospholipidosis inducers?","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.06.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}