{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:50:21Z","timestamp":1786985421225,"version":"build-2736575974"},"reference-count":9,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.bmcl.2014.08.016","type":"journal-article","created":{"date-parts":[[2014,8,13]],"date-time":"2014-08-13T22:48:09Z","timestamp":1407970089000},"page":"4410-4413","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis for the instability of trioxacarcin A"],"prefix":"10.1016","volume":"24","author":[{"given":"Kevin","family":"Pr\u00f6pper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birger","family":"Dittrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Smaltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Magauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew G.","family":"Myers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2014.08.016_b0005","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.7164\/antibiotics.34.1519","volume":"34","author":"Tomita","year":"1981","journal-title":"J. Antibiot."},{"key":"10.1016\/j.bmcl.2014.08.016_b0010","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.7164\/antibiotics.34.1525","volume":"34","author":"Tamaoki","year":"1981","journal-title":"J. Antibiot."},{"key":"10.1016\/j.bmcl.2014.08.016_b0015","doi-asserted-by":"crossref","first-page":"771","DOI":"10.7164\/antibiotics.57.771","volume":"57","author":"Maskey","year":"2004","journal-title":"J. Antibiot."},{"key":"10.1016\/j.bmcl.2014.08.016_b0020","doi-asserted-by":"crossref","first-page":"3508","DOI":"10.1093\/nar\/gkn245","volume":"36","author":"Pfoh","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bmcl.2014.08.016_b0025","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1002\/anie.200352312","volume":"43","author":"Maskey","year":"2004","journal-title":"Angew. Chem., Int. Ed."},{"key":"10.1016\/j.bmcl.2014.08.016_b0030","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/nchem.1746","volume":"5","author":"Magauer","year":"2013","journal-title":"Nat. Chem."},{"key":"10.1016\/j.bmcl.2014.08.016_b0040","unstructured":"Crystallographic data for 6 and 7 were measured at the Swiss Light Source synchrotron at the macromolecular beamline X10SA using a wavelength of 0.6358\u00c5. Fine slicing data collection was performed according to the protocol established earlier (Mueller, M.; Wang, M.; Schulze-Briese, C. Acta Crystallogr., Sect. D 2012, 68, 42.). Due to the small crystal size the use of synchrotron radiation was necessary. Data integration was performed with the XDS software (Kabsch, W. Acta Crystallogr., Sect. D 2010, 66, 125.). Structure solution and refinement were carried out with SHELXS and SHELXL (Sheldrick, G. Acta Crystallogr., Sect. A 2008, 64, 112.). The X-ray crystal structure of 6 has been deposited at the Protein Data Bank (PDB ID 4HP7). The X-ray crystal structure of 7 has been deposited at the Cambridge Crystallographic Data Centre (deposition number 1004232)."},{"key":"10.1016\/j.bmcl.2014.08.016_b0045","first-page":"199","volume":"24","author":"Shirahata","year":"1981","journal-title":"Symp. Chem. Nat. Prod."},{"key":"10.1016\/j.bmcl.2014.08.016_b0050","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1021\/tx00019a001","volume":"4","author":"Gaudiano","year":"1991","journal-title":"Chem. Res. Toxicol."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X14008476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X14008476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T06:54:18Z","timestamp":1760770458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X14008476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":9,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0960894X14008476"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2014.08.016","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis for the instability of trioxacarcin A","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2014.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}