{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T05:10:13Z","timestamp":1773724213149,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009873","name":"Regione Autonoma della Sardegna","doi-asserted-by":"crossref","award":["LR 7\/2007 CRP-24915"],"award-info":[{"award-number":["LR 7\/2007 CRP-24915"]}],"id":[{"id":"10.13039\/501100009873","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.bmcl.2015.05.076","type":"journal-article","created":{"date-parts":[[2015,5,30]],"date-time":"2015-05-30T11:49:34Z","timestamp":1432986574000},"page":"3281-3284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII"],"prefix":"10.1016","volume":"25","author":[{"given":"Rita","family":"Meleddu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elias","family":"Maccioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Distinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Bianco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Melis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Alcaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Cottiglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariangela","family":"Ceruso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2015.05.076_b0005","doi-asserted-by":"crossref","first-page":"30766","DOI":"10.1074\/jbc.M805353200","volume":"283","author":"Domsic","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bmcl.2015.05.076_b0010","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","volume":"112","author":"Alterio","year":"2012","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmcl.2015.05.076_b0015","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1152\/physrev.2000.80.2.681","volume":"80","author":"Geers","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bmcl.2015.05.076_b0020","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.bbapap.2009.10.021","volume":"1804","author":"Boron","year":"2010","journal-title":"Biochim. Biophys. Acta, Proteins Proteomics"},{"key":"10.1016\/j.bmcl.2015.05.076_b0025","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.bmc.2012.04.044","volume":"21","author":"Imtaiyaz Hassan","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2015.05.076_b0030","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1165\/rcmb.2014-0054OC","volume":"52","author":"Zhou","year":"2015","journal-title":"Am. J. Resp. Cell. Mol. Biol."},{"key":"10.1016\/j.bmcl.2015.05.076_b0035","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.2174\/092986710790979999","volume":"17","author":"Guler","year":"2010","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bmcl.2015.05.076_b0040","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10555-007-9064-0","volume":"26","author":"Swietach","year":"2007","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.bmcl.2015.05.076_b0045","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/med.20112","volume":"28","author":"Winum","year":"2008","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bmcl.2015.05.076_b0050","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","volume":"20","author":"Supuran","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2015.05.076_b0055","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/ja809683v","volume":"131","author":"Maresca","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bmcl.2015.05.076_b0060","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1039\/C4CC07320G","author":"D\u2019Ambrosio","year":"2015","journal-title":"Chem. Commun. (Cambridge, U.K.)"},{"key":"10.1016\/j.bmcl.2015.05.076_b0065","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1517\/13543776.2012.698264","volume":"22","author":"Carta","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.bmcl.2015.05.076_b0070","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.ejmech.2013.06.003","volume":"66","author":"Suthar","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2015.05.076_b0075","doi-asserted-by":"crossref","unstructured":"Al-Rashida, M.; Hussain, S.; Hamayoun, M.; Altaf, A.; Iqbal, J. BioMed Res. Int. 2014, 162928\/1.","DOI":"10.1155\/2014\/162928"},{"key":"10.1016\/j.bmcl.2015.05.076_b0080","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1021\/ml500196t","volume":"5","author":"Pala","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.bmcl.2015.05.076_b0085","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1107\/S0907444910006554","volume":"66","author":"Behnke","year":"2010","journal-title":"Acta Crystallogr., Sect. D"},{"key":"10.1016\/j.bmcl.2015.05.076_b0090","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","volume":"60","author":"Emsley","year":"2004","journal-title":"Acta Crystallogr., Sect. D"},{"key":"10.1016\/j.bmcl.2015.05.076_b0095","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1021\/ar000033j","volume":"33","author":"Kollman","year":"2000","journal-title":"Acc. Chem. Res."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X15005508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X15005508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:03:37Z","timestamp":1760771017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X15005508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":19,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0960894X15005508"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2015.05.076","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2015.05.076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}