{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:54:56Z","timestamp":1771469696083,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"23","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["F.30-106\/2015-BSR"],"award-info":[{"award-number":["F.30-106\/2015-BSR"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001427","name":"All India Council for Technical Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001427","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"UGC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.bmcl.2016.10.058","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T18:17:38Z","timestamp":1478024258000},"page":"5712-5718","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["First molecular modeling report on novel arylpyrimidine kynurenine monooxygenase inhibitors through multi-QSAR analysis against Huntington\u2019s disease: A proposal to chemists!"],"prefix":"10.1016","volume":"26","author":[{"given":"Sk. Abdul","family":"Amin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilanjan","family":"Adhikari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarun","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shovanlal","family":"Gayen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2016.10.058_b0005","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1021\/jm501350y","volume":"58","author":"Toledo-Sherman","year":"2015","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0010","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.drudis.2015.11.001","volume":"21","author":"Smith","year":"2016","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.bmcl.2016.10.058_b0015","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nature12039","volume":"496","author":"Amaral","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2016.10.058_b0020","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1471-4159.2005.03070.x","volume":"93","author":"Stoy","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0025","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1093\/hmg\/ddp527","volume":"19","author":"Mazarei","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bmcl.2016.10.058_b0030","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00018-009-0166-4","volume":"67","author":"Han","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bmcl.2016.10.058_b0035","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.cub.2011.04.028","volume":"21","author":"Campesan","year":"2011","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bmcl.2016.10.058_b0040","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/nrd870","volume":"1","author":"Stone","year":"2002","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bmcl.2016.10.058_b0045","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/978-1-4615-0135-0_15","volume":"527","author":"Moroni","year":"2003","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bmcl.2016.10.058_b0050","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/nm1196","volume":"11","author":"Muller","year":"2005","journal-title":"Nat. Med."},{"key":"10.1016\/j.bmcl.2016.10.058_b0055","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jns.2005.07.006","volume":"239","author":"Hartai","year":"2005","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.bmcl.2016.10.058_b0060","doi-asserted-by":"crossref","first-page":"204","DOI":"10.2478\/v10039-010-0023-6","volume":"55","author":"Gulaj","year":"2010","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.bmcl.2016.10.058_b0065","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nrn3257","volume":"13","author":"Schwarcz","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bmcl.2016.10.058_b0070","first-page":"1","volume":"1","author":"Dearden","year":"2016","journal-title":"Int. J. Quant. Struct. Propert. Relat."},{"key":"10.1016\/j.bmcl.2016.10.058_b0075","series-title":"Understanding the basics of QSAR for applications in pharmaceutical sciences and risk assessment","author":"Roy","year":"2015"},{"key":"10.1016\/j.bmcl.2016.10.058_b0080","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1021\/cr0780210","volume":"109","author":"Verma","year":"2009","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bmcl.2016.10.058_b0085","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1016\/j.bmc.2007.01.011","volume":"15","author":"Verma","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0090","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1002\/jcc.21707","volume":"32","author":"Yap","year":"2011","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chemolab.2015.07.007","volume":"147","author":"Ambure","year":"2015","journal-title":"Chemo. Intell. Lab. Sys."},{"key":"10.1016\/j.bmcl.2016.10.058_b0100","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jtusci.2016.04.009","volume":"10","author":"Amin","year":"2016","journal-title":"J. Taibah Univ. Sci."},{"key":"10.1016\/j.bmcl.2016.10.058_b0105","doi-asserted-by":"crossref","first-page":"84","DOI":"10.2174\/1570163813666160429115628","volume":"13","author":"Amin","year":"2016","journal-title":"Curr. Drug Discov. Technol."},{"key":"10.1016\/j.bmcl.2016.10.058_b0110","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2174\/15734099113099990014","volume":"9","author":"Adhikari","year":"2013","journal-title":"Curr. Comp. Aid. Drug Des."},{"key":"10.1016\/j.bmcl.2016.10.058_b0115","unstructured":"The simple, user-friendly and reliable online standalone tools freely available at http:\/\/dtclab.webs.com\/software-tools."},{"key":"10.1016\/j.bmcl.2016.10.058_b0120","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/j.tiv.2015.05.017","volume":"29","author":"Adhikari","year":"2015","journal-title":"Tox. In Vit."},{"key":"10.1016\/j.bmcl.2016.10.058_b0125","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.ejmech.2014.12.011","volume":"90","author":"Mondal","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0130","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1139\/cjc-2016-0050","volume":"94","author":"Amin","year":"2016","journal-title":"Can. J. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0135","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S1093-3263(01)00123-1","volume":"20","author":"Golbraikh","year":"2002","journal-title":"J. Mol. Graph. Model."},{"key":"10.1016\/j.bmcl.2016.10.058_b0140","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.chemolab.2011.03.011","volume":"107","author":"Ojha","year":"2011","journal-title":"Chemo. Intell. Lab. Syst."},{"key":"10.1016\/j.bmcl.2016.10.058_b0145","first-page":"45","volume":"1","author":"Gadaleta","year":"2016","journal-title":"Int. J. Quant. Struct. Propert. Relat."},{"key":"10.1016\/j.bmcl.2016.10.058_b0150","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.chemolab.2015.04.013","volume":"145","author":"Roy","year":"2015","journal-title":"Chemo. Intell. Lab. Syst."},{"key":"10.1016\/j.bmcl.2016.10.058_b0155","series-title":"Molecular Descriptors for Chemoinformatics (2 volumes)","first-page":"1257","author":"Todeschini","year":"2009"},{"key":"10.1016\/j.bmcl.2016.10.058_b0160","doi-asserted-by":"crossref","first-page":"28171","DOI":"10.1039\/C6RA04104C","volume":"6","author":"Ambure","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.bmcl.2016.10.058_b0165","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.chemolab.2016.01.008","volume":"152","author":"Roy","year":"2016","journal-title":"Chemo. Intell. Lab. Syst."},{"key":"10.1016\/j.bmcl.2016.10.058_b0170","first-page":"453","volume":"11","author":"Mandi","year":"2012","journal-title":"EXCLI J."},{"key":"10.1016\/j.bmcl.2016.10.058_b0175","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jmgm.2008.04.005","volume":"27","author":"Nantasenamat","year":"2008","journal-title":"Mol. Graph Model."},{"key":"10.1016\/j.bmcl.2016.10.058_b0180","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1021\/ci0601315","volume":"46","author":"Klon","year":"2006","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.bmcl.2016.10.058_b0185","series-title":"Discovery Studio 3.0, San Diego, USA","author":"Accelrys Inc","year":"2011"},{"key":"10.1016\/j.bmcl.2016.10.058_b0190","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1021\/jm010360c","volume":"45","author":"Debnath","year":"2002","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bmcl.2016.10.058_b0195","unstructured":"Autodock Vina, Molecular Graphics Lab, The Scripps Research Institute, La Jolla, CA 92037, USA."}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X16310964?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X16310964?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:11:39Z","timestamp":1760771499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X16310964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":39,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0960894X16310964"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2016.10.058","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"First molecular modeling report on novel arylpyrimidine kynurenine monooxygenase inhibitors through multi-QSAR analysis against Huntington\u2019s disease: A proposal to chemists!","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2016.10.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}